Two new graduate students, Haoran and Matthew, joined the lab. Haoran is a first year student in the Biochemistry Ph.D. program, and will be working on the Moco project and the mechanism of radical SAM enzymes in general. Matthew is a third year student in the MSTP (M.D. Ph.D.) program and the first year in the Ph.D. phase. Matthew will work on the biosynthesis of antifungal natural products and its application to development of novel antifungal agents. Welcome on board and let’s enjoy the sicence together!!
We are interested in the functions and mechanisms of enzymes involved in the biosynthesis of natural products and cofactors as well as those in fungal cell wall biosynthesis. The target enzymes play essential roles in inheritable human disease, or bacterial or fungal infectious disease. We aim to understand the mechanisms of these enzymes and use the knowledge to discover novel therapeutics. Specifically, we are interested in:
