Bach received a fellowship from the Triangle Center of Evolutional Medicine to study the natural evolution of naturally-occurring peptide antibiotics. While >60% of FDA-approved antibiotics originate from Nature, how these antibiotics evolved is largely unexplored. In this project, Bach will study the evolutional course of antibiotics using the recently discovered ribosomally synthesized and posttranslationally modified peptides (RiPPs) antibiotics. The results will provide novel insights into the natural evolution of antibiotics and may reveal an evolution-based approach to discovering novel antibiotics. Congratulations, Bach!
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Recent Entries
- Bach received TriCEM fellowship to study the natural evolution of antibiotics
- Hai’s paper on the discovery of radical SAM oxygenase is published in JACS
- Elisha and Rachel presented posters at SURF
- Chitin synthase structure paper was published in Nature Structural & Molecular Biology
- Haoran successfully defended his Ph.D. dissertation
- Our latest manuscript about malayamycin biosynthesis was published in ACS Chemical Biology
- Haoran received 2021-2022 Chancellor’s Award for Research Excellence (CARE)
- Our perspective on MoaA and MoaC is published in ACS Bio Med Chem Au
- Haoran’s paper is highlighted in JACS Spotlight
- Haoran’s paper is published in JACS.
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