Hai’s paper on mitomycin biosynthesis was published

Hai’s work on the characterization of MitE and MitB enzymes in mitomycin biosynthesis was published in ACS Biochemistry. In this paper, we provide experimental evidence that the early steps of mitomycin biosynthesis proceeds with the biosynthetic intermediates linked to an acyl carrier protein (ACP). This is one of the first examples of ACP-dependent non-PKS/NRPS pathways, and the first step towards understanding the complex mechanism of mitomycin biosynthesis.

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