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Yang Lab

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SCD
PIEZO1 in placenta
TCS
Absence seizure
Flip-flop
Channel
Amazingly ‘simple’ cell? Red blood cells
Fusion
Models
Ephys
Channelopathy

A postdoctoral position is immediately open for a motivated scientist with experience in ion channel biology, neurobiology, and membrane biology. Contact Huanghe Yang (huanghe.yang@duke.edu) to apply. 

Welcome to the membrane transport lab!

We study the biology of ion and lipid flip-flop across cell membranes in the nervous system and beyond. We currently focus on ion channels and lipid scramblases, including but not limited to the TMEM16 protein family.

What We’re Pursuing?

  1. What are the molecular mechanisms of ion and lipid transport across cell membranes?
  2. How do ion and lipid transport systems regulate health and contribute to disease?
  3. How can we target ion and lipid transport pathways for therapeutic development?

What We’ve Discovered?

Our Techniques and Approaches

  • in vitro and in vivo electrophysiology
  • in vitro and in vivo optical imaging
  • Mouse models
  • Behavioral physiology
  • Pharmacology
  • Biochemistry and biophysics
  • Blood coagulation assays

Do meaningful science.