The National Institutes of Health’s Office of Disease Prevention (ODP) has just released a free, self-paced online course on designing and analyzing pragmatic and group-randomized trials. The course, which is presented by ODP Director Dr. David Murray, includes a series of seven video presentations plus slide sets, reference materials, and guided activities.
Course segments typically last 25 to 35 minutes. Presentations can be accessed individually and include the following topics:

- Part 1: Introduction and Overview
- Part 2: Designing the Trial
- Part 3: Analysis Approaches
- Part 4: Power and Sample Size
- Part 5: Examples
- Part 6: Review of Recent Practices
- Part 7: Alternative Designs
The course is designed for faculty, fellows, and graduate students who have had training in the basics of research design and regression analysis. Part 5 (“Examples”) of the presentation includes multiple examples drawn from NIH Collaboratory Demonstration Projects, including the Strategies and Opportunities to Stop Colorectal Cancer (STOP-CRC), Collaborative Care for Chronic Pain in Primary Care (PPACT), Trauma Survivors Outcomes and Support (TSOS), and Improving Chronic Disease Management with Pieces (ICD-PIECES) studies.