Author Archives: Cristian Badea

A photon counting CT imaging pipeline for cardiac phenotyping in APOE mice

Posted on October 8, 2023 by Cristian Badea

Our new study develops an advanced imaging pipeline using photon-counting CT to assess cardiac structure & function in mouse models of apolipoprotein E gene variations. Results highlight genotype-specific cardiovascular differences and the impact of diet. Allphin, A. J., Mahzarnia, A., … Continue reading →

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Leveraging 3D Bioprinting & Photon-Counting Computed Tomography for Regenerative Medicine

Posted on September 17, 2023 by Cristian Badea

An exciting publication on our collaborative research focusing on the innovative applications of 3D Bioprinting and Photon-Counting CT. Gil CJ, Evans CJ, Li L, Allphin AJ, Tomov ML, Jin L, Vargas M, Hwang B, Wang J, Putaturo V, Kabboul G, … Continue reading →

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Deep Learning Denoising for Photon-Counting CT

Posted on July 16, 2023 by Cristian Badea

Nadkarni, R.; Clark, D.P.; Allphin, A.J.; Badea, C.T. A Deep Learning Approach for Rapid and Generalizable Denoising of Photon-Counting Micro-CT Images. Tomography 2023, 9, 1286-1302. https://doi.org/10.3390/tomography9040102

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MCR toolkit

Posted on June 7, 2023 by Cristian Badea

Our QIAL developed Multi-Channel CT Reconstruction (MCR) Toolkit addresses unique challenges associated with in vivo preclinical micro-CT and supporting the translation of these advancements to the clinical domain. We have now published a paper in Medical Physics detailing our toolkit’s … Continue reading →

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Co-Clinical Imaging

Posted on May 11, 2023 by Cristian Badea

Our group contributed to these new papers from the co-clinical imaging research program (CIRP) : 1.Moore, S.M.; Quirk, J.D.; Lassiter, A.W.; Laforest, R.; Ayers, G.D.; Badea, C.T.; Fedorov, A.Y.; Kinahan, P.E.; Holbrook, M.; Larson, P.E.Z.; Sriram, R.; Chenevert, T.L.; Malyarenko, … Continue reading →

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QIAL papers at SPIE Medical Imaging 2023

Posted on May 4, 2023 by Cristian Badea

1)  A Allphin, R Nadkarni, D Clark, C T Badea. Ex vivo high-resolution hybrid micro-CT imaging using photon counting and energy integrating detectors. Proc. of SPIE Vol 12468, 124680V-1, 2023 2) DP Clark, FR Schwartz, A Euler, V Mergen, H … Continue reading →

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Denoising dual-energy abdominal CT of obese patients

Posted on April 21, 2023 by Cristian Badea

The purpose of this study was to evaluate a novel algorithm for noise reduction in obese patients for dual-source dual-energy (DE) CT abdominal imaging. We demonstrated that multi-channel denoising methods (RSKR, multi-energy (ME)-NLM) could reduce image noise and improve both … Continue reading →

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Spectral CT imaging using GaAs and CdTe photon counting detectors

Posted on April 6, 2023 by Cristian Badea

In this study, we compared the performance of PC micro-CT imaging when using two types of PCDs. We have also demonstrated the ability of PCDs to separate a wide range of K-edge materials. Alex Jeffrey Allphin, Darin P Clark, Thomas … Continue reading →

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Group Photo

Posted on March 21, 2023 by Cristian Badea

QIAL members and the Bass Connections team, March 2023 Artist and T-shirts Designer: Nariman (Ali) Mahzarnia  

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Animal Models and Their Role in Imaging-Assisted Co-Clinical Trials

Posted on March 16, 2023 by Cristian Badea

This overview paper describes the ten co-clinical trials of investigators from eleven institutions who are supported by the CIRP initiative and are members of the Animal Models and Co-clinical Trials (AMCT) Working Group. Examples of MRI and micro-CT images in … Continue reading →

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