Metabolic Function in AKI

Image courtesy of Front Physiol. 2021;12:683098.

Our laboratory studies metabolic and mitochondrial function in both immune cells and kidney tubular cells. Our laboratory is funded to study the effects of an annexin A1 peptide mimetic that can augment mitochondrial ATP production and limit mitochondrially-mediated cell death in the kidney following ischemia. We are also studying mechanisms in which immune cells and tubular cells interact to improve mitochondrial quality control.