Pathology

The PTRU has access to Duke’s pathology core facility.  This core facility is a state-of-the-art lab that provides routine and specialized histological services, as well as immunohistochemical stains. As with many of the resources to which partnership with the PTRU provides access, the size and scope of Duke’s pathology core provides benefits not achievable in smaller more isolated research environments. Duke’s pathology core laboratory is used heavily, with approximately 9500 paraffin blocks embedded during the past year and 72,000 slides prepared.  Approximately 5600 immunohistochemical stains were performed during the past year. The expert staff provides detailed and careful assistance with respect to every aspect of their pathology services from the proper collection and fixation of the tissue to immunohistochemical staining procedures to the evaluation of the stains.
The pathology core includes a dedicated Electron Microscopy Service. This resource provides high quality light and electron micrographs and is the longest continuously running shared service facility on campus with a history of almost four decades. This facility provides a full range of sample preparation, technical assistance, and training in viewing and photographing specimens. The Electron Microscopy Service expertly supplies ultrastructural analyses of small specimens including:

  • Cells and tissues
  • Subcellular organelles
  • Microorganisms such as viruses, bacteria, fungi, and parasites

They also provide:

  • Assistance in design and execution of experimental procedures
  • Training on use and operation of equipment
  • Data acquisition and analysis

To see a full list of pathology core services click here.