Comparison of frequency of frailty and severely impaired physical function in patients ≥60 years hospitalized with acute decompensated heart failure vs chronic stable heart failure with reduced and preserved left ventricular ejection fraction.
The American Journal of Cardiology (2016), doi: 10.1016/j.amjcard.2016.03.046.
Authors: Reeves GR, Whellan DJ, Patel MJ, O’Conner CM, Duncan P, Eggebeen JD, Morgan TM, Hewston LA, Pastva AM, Kitzman DW.
Older patients with acute decompensated heart failure are frequently frail with severe and widespread impairments in physical function, cognition, mood, and quality of life that may contribute to their persistently poor outcomes, are often unrecognized, are not addressed in current ADHF paradigms, and may be potentially modifiable with targeted interventions. Based on these findings, we developed a novel rehabilitation intervention to address the severe physical function deficits, which is currently being tested in a recently launched, multi center NIH-funded clinical trial: A Trial of Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) (ClinicalTrials.gov Identifier: NCT02196038).