Bioinformatics Group

The DMC Bioinformatics Group applies algorithmic, statistical, and mathematical techniques to solve problems of interest to microbial scientists. The Bioinformatics Group provides a walk-in service for consultations and computational support, and a variety of training workshops.  Investigators work with the GeMS Bioinformatics Group on (1) a collaborative basis and (2) a core service basis through the GCB Genomic Analysis Bioinformatics Shared Resource. For consultations on new or existing projects, please contact Joshua Granek, PhD.

Joshua Granek, PhD
Dr. Granek interests are centered in interactions between organisms at the cellular and molecular scale, with a research focus on microbial communities and pathogens. Throughout his career, he has used a combination of experimental and computational approaches to address biological questions ranging from the structure, organization, and evolution of transcription regulatory sequences, through the development of GOMER, a software package for modeling transcriptional regulation on a genomic scale, to wet-lab experiments that analyzed the regulation of ploidy specific genes in the yeast Saccharomyces cerevisiae. He also developed S. cerevisiae colony biofilms as a model for understanding how microbes interact to generate multicellular behavior using a combination of genome-scale techniques, including next-generation DNA sequencing, high-throughput phenotyping, and computation. Dr. Granek’s current efforts are focused on supporting various microbial labs with the analysis of high-throughput genomic DNA and RNA sequencing data in both bacterial and fungal systems. Dr. Granek’s primary appointment is in the Department of Biostatistics and Bioinformatics and the Department of Molecular Genetics and Microbiology.
Joshua Granek, PhD
Assistant Research Professor
Dept. of Biostatistics & Bioinformatics
Tel: 919.684.2876