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Amanda S MacLeod, MD  (nee Büchau)

Associate Professor of Dermatology

Assistant Professor of Immunology

Assistant Professor of Molecular Genetics and Microbiology

Departmental Director for Physician Scientist Development

Member of the Center for Host-Microbiome Interactions (CHoMI), DCI Member, Member of the Duke Microbiome Center, Affiliate of Regeneration Next, Member and Graduate Faculty of the Developmental and Stem Cell Biology Program, Affiliate Member of the Children’s Health  and Discovery Initiative

Education: MD, Heinrich Heine University Düsseldorf (Germany), 2005

 

Biography

Dr. Amanda MacLeod received her Abitur (B.S. equivalent) from the Cecilien-Gymnasium in Dusseldorf, Germany and her M.D. degree from the Heinrich-Heine University in Düsseldorf, Germany. She entered dermatology residency training under Dr. Thomas Ruzicka at the Heinrich-Heine University (Dusseldorf) and Ludwig Maximilian University (Munich) and had her postdoctoral training with Dr. Richard Gallo at UCSD and Dr. Wendy Havran at the Scripps Research Institute. After receiving a NIH K08 Career Development Award, Dr. MacLeod was recruited as Assistant Professor to the Department of Dermatology at Duke University in 2014 and received her promotion to Associate Professor in 2019. She runs a successful  R01-funded translational research laboratory aimed at understanding skin barrier immunity, host-microbial interactions, wound repair and regeneration in inflammatory and infectious skin diseases. Dr. MacLeod authored and co-authored over 50 research articles, clinical case reports, invited previews and review articles in journals including the Journal for Investigative Dermatology, Journal of Clinical Investigation, Science, Trends in Immunology, Journal of Immunology, Cell Host and Microbe, Plos One, Plos Pathogens, Science Signaling, Science Translational Medicine, Advances in Wound Care and many more. Dr. MacLeod received numerous honors and awards, including summa cum laude (BS), a Research Fellowship from the Deutsche Forschungsgemeinschaft (DFG) and the 2009 Research Award Prize from Arbeitsgemeinshaft Dermatologische Forschung, a NIH K08 Career Development Award, the Physician-Scientist Strong Start Award, and most recently she was named a top 40 under 40  recipient by the Triangle Business Journal (TBJ). She was invited to give a  Distinguished Lectureship at the University of Luebeck. Dr. MacLeod has served as Associate Review Editor for Frontiers in Immunology, and is now Associate Editor for Frontiers in Cellular and Infection Microbiology.  Dr. Macleod served  as Associate Residency Program Director for Research in the Department for Dermatology and now is Director for Physician Scientist Development in the Department of Dermatology. Nationally, she serves as co-chair on the Committee for Education for the Society for Investigative Dermatology, on the committee for Diversity and Inclusion for the Society for Investigative Dermatology, and as Scientific Evaluation Review Member for the LEO Foundation. She is active in promoting and advocating for women (and men), and underrepresented minorities in medicine and science. At Duke, Dr. MacLeod serves or has served on multiple PhD committees as well as on the MSTP admission and the dermatology residency admission committee. Dr. MacLeod organized, chaired or co-chaired multiple symposia and conferences and also consults/has consulted for Silab and Novartis.

 

 

IMG_0686Jutamas Suwanpradid, PhD
Research Laboratory Analyst II

Jutamas joined the MacLeod Lab as Postdoctoral Associate early in 2015 after her graduation from Georgia Regents University with a PhD in Biomedical Sciences. Before that, she received her BA of Pharmacy with Distinction in Quality Assurance from Chulalongkorn University in Thailand. In 2019, she was promoted to Research Laboratory Analyst II.

In the MacLeod Lab, Jutamas’ work focuses on cellular and molecular regulation of immune responses in allergic contact dermatitis and squamous cell carcinoma.  She also is an excellent mentor for undergrads and grad  and medical students in the lab and hels the lab rtun smooth on day-to-day operations.

When not in the lab, Jutamas enjoys perfecting her favorite Thai food recipes.

 

Paula Mariottoni (nee Borges), MD

Postdoctoral Fellow

Paula is a dermatologist from Brazil and she joined the MacLeod lab in the fall of 2017. She received her MD degree from  Paulista State University. Her projects are aimed at understanding host-microbial interaction in the skin and how these direct immune responses.

 

 

Chelsea Handfield
(2nd) Third Year Medical Student, MD Candidate, Poindexter Fellow (2017), Stead Scholar (2018)

Chelsea joined the MacLeod lab for her third year of medical school research rotation (2017) and she is staying on for her second Third year!! She already published a beautiful Trends in Immunology Review Article and continues her research on the regulation of antimicrobial proteins in the skin.

When not in the lab, Chelsea enjoys exploring the Triangle area and cooking.

 

headshotJeff Kwock
(2nd) Third Year Medical Student, MD Candidate, Stead Scholar (2016-18)

Jeff is remaining in the MacLeod lab for a 2nd third year of medical school research rotation. His research focuses on the role of Interleukin-27 induction of anti-viral proteins upon wounding. Jeff received his BS from the University of Hawaii.

When not toiling away in the lab, Jeff enjoys spending time with his partner, and improving his Ukulele skills.

 

 

Jessica Shannon

Immunology PhD Grad Student

With a passion for immunology, Jess joined the MacLeod. When not in lab, Jess enjoys hiking, lifting weights, watching Duke basketball, painting, and exploring the Triangle area

 

 

Stephen Kirchner

MGM MSTP Grad Student

Stephen is a MD/PhD student in the MGM department who joined the MacLeod Lab in January of 2019. His research interests include the expression and regulation of antiviral proteins in the skin, and these proteins’ impact on various disease states including skin cancer. The only thing as important as the lab to Stephen is his beloved Duke Blue Devils. In his spare time, he enjoys all sports, spending time with his dog, gardening and grilling.

 

 

Min Jin Lee

DSCB/MGM PhD Grad student

Min Jin joined the MacLeod lab in the fall of 2018. Her work is focused on deciphering innate immune responses in skin regenerative processes and stem cells.

 

 

Vivian Lei

Second Third Year Medical Student, MD Candidate

Vivian is a second Third Year Medical Student at Duke School of Medicine. Her Research interests focus on understanding the development, regulation, and maturation of innate antiviral immunity in the skin.

 

 

Melodi Javid Whitley, MD, PhD

Dermatology Resident, Physician-Investigator Track

Melodi is a Duke Dermatology resident pursuing a career in academic dermatology. She received her BS in Biochemistry and BA in Spanish Language and Literature in 2007 from University of Maryland, College Park. She went on to a post-baccalaureate intramural research training award at the NIH studying HIV within the NIAID prior to arriving at Duke in 2009 to pursue an MD-PhD in the Medical Scientist Training Program.  In 2017 she graduated from Duke School of Medicine with her MD and a PhD in Molecular Cancer Biology which she completed in the Kirsch lab. After completing an internship in Internal Medicine, she joined the Dermatology Department as a resident in the Physician-Investigator Track.  Her focus in the MacLeod lab is to further understand the role of innate immunity and immunosuppression in the pathogenesis of non-melanoma skin cancers.

Outside of the lab, Melodi enjoys her clinical work, spending time with husband and son, as well as staying active through running, spin, and Pilates.

 

Maggie Coates

Third Year Medical Student, Poindexter Fellow (2018)

Maggie joined the MacLeod lab in fall of 2018 for her Third Year of medical school research. Her research focus is on the intersection of the cutaneous microbiome with wounds and inflammatory skin diseases. Outside of lab, Maggie enjoys outdoor running, showing her competitive side over board games, and cuddling with her dog, Ollie.

 

 

Gerry
White Blood Cell, Lab Security

Gerry was a gift to the lab from Michael Shih, a former undergraduate independent study researcher.

Since his arrival, Gerry has contributed to the lab goals in immeasurable ways. His shoulder is always available to cry on when experiments don’t go as planned. He deftly de-escalates lab crisis simply by looking cute. He watches the lab like a hawk from his perch on the front door.

When not performing his indispensable duties in the lab, Gerry enjoys long walks in the desert, and inventing last names for himself.