The learning of sequential relationships is thought to underlie much of our behavior, allowing us to acquire new routines and adapt to changing environments. Traditionally, this has been studied using continuous streams of stimuli; however, my colleagues created a paradigm with a distinct trial structure, the Triplets Learning Task, allowing us to examine sequence learning using neuroimaging techniques (i.e. Stillman et al 2014). We found age deficits in sequence learning are linked to reduced structural (Seaman, Stillman, Howard & Howard, 2014 SfN) and functional (Stillman, Seaman et al, 2016) connectivity. Collectively, these studies support a growing consensus that sequence learning is supported by multiple brain systems.