Welcome to HARP at Duke University!

We are an interdisciplinary team that seeks to improve the lives of people with HIV who use addictive drugs. The overarching goal of HARP is to advance our understanding of how HIV infection and drug abuse can alter neurobehavioral outcomes. To this end, our research integrates multimodal neuroimaging technologies with behavioral assessment strategies and clinical measures. We focus on a wide range of drugs, including marijuana, cocaine, and opioids. Our research also investigates neurobehavioral predictors of risk behaviors and health outcomes among active drug users, including reducing health disparities. The HARP team is committed to inclusivity and employs recruitment strategies to reach diverse groups, including those with minimal access to healthcare.


Permanent link to this article: https://sites.duke.edu/harp/

HARP awarded a new R01 grant from NIDA

This 5-year grant entitled, Modeling the effects of chronic marijuana use on neuroinflammation and HIV-related neuronal injury, was awarded to Dr. Christina Meade (PI) and Dr. Sheri Towe (Co-I) in the HIV and Addictions Research Program at Duke. The hypothesis-drived proposal will investigate the underlying pathophysiological mechanisms of HIV-associated brain dysfunction and the mechanisms through which …

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New pub on the potential for PrEP in persons who use stimulant drugs

The HARP team recently published an article titled “Examining the Potential of Pre‑exposure Prophylaxis (PrEP) for HIV Prevention in a Community Sample of Persons Who Use Stimulants Living in the Southern United States” in AIDS and Behavior. Of 352 participants, over half (61%) met criteria for PrEP candidacy, but less than 20% had heard of PrEP. …

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Web-based cognitive training is a promising intervention for improving working memory

The HARP team recently published a journal article titled “Web‑Based Cognitive Training to Improve Working Memory in Persons with Co‑Occurring HIV Infection and Cocaine Use Disorder: Outcomes from a Randomized Controlled Trial” in AIDS and Behavior. The aim of this paper was to examine the feasibility and effectiveness of a web-based cognitive training intervention to …

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Study finds high HIV prevalence in North Carolinians who use stimulant drugs

In a new paper published in AIDS and Behavior,  the HARP team reported the prevalence of HIV infection and risk behaviors among persons who use illicit stimulant drugs in the greater Raleigh-Durham area. Using respondent driven sampling (RDS), the team engaged 387 participants from seven initial “seeds”, as demonstrated in this figure. Participants predominantly used …

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