Depth of Anesthesia Monitor

Hospitals need safe and easy-to-use muscle paralysis monitors. During surgeries requiring general anesthesia, anesthesiologists use neuromuscular blocking agents (NMBAs) in addition to analgesics. It is essential to monitor blockage to correctly time intubation, guide intraoperative administration of NMBAs, predict spontaneous recovery, and prevent residual weakness post-operation. Examination of muscle movement using clinical criteria has shown to be inadequate, and residual paralysis can lead to impaired esophageal function, pulmonary complications, and respiratory failure.

We are working to develop a monitor which incorporates train-of-four (TOF) muscle stimulation of the ulnar nerve, electromyography, a user-modifiable signal for adjustable electrode placement, and a straightforward interface. This project is conducted under Dr. Mark Palmeri and in collaboration with Dr. Stuart Grant. This is not only a learning experience with regards to the engineering design process, but we hope to use what we’ve learned in the engineering curriculum to bring a product to the market.

During this process, we conduct research on clinical standards, FDA regulations, ethical concerns, and intellectual property rights and protections related to our medical device. With these in mind, we design feasibility and safety tests to meet those standards, leading to various stages of prototypes. Additionally, we interact extensively with our clients, learn about marketing strategies, and conduct market analysis. Through this endeavor, I can truly understand the processes and business models involved with bringing a product to market for the successful implementation of Grand Challenge Solutions.


Start date: August 28, 2017

Projected end date: May, 2018

Hours per week: 10 hours