Mackenzie Smith
4th year, PhD Candidate
Chemistry
Previous educational background: B.S. Biochemistry, Biology, and Chemical Biology with a minor in Environmental Studies; Brandeis University
Research Project: My research project focuses on the antifungal action of histatin-5. Of particular interest is the effect essential metals have on that antifungal activity. I use cellular assays along with fluorescence microscopy and other chemical biology techniques to unravel the mysteries of histatin-5.
Personal Bio: I am an avid soccer fan and enjoy following the local teams in the area as well as my EPL team. When not watching soccer, I enjoy cooking and baking treats for the lab as well as going on outdoor adventures in the woods and out by the coast!
Publications:
Zhao, H.; Kumar, P.; Sobreira, T. J. P.; Smith, M.; Novick, S.; Johansson, A.; Luchniak, A.; Zhang, A.; Woollard, K. J.; Larsson, N.; et al. Integrated Proteomics Characterization of NLRP3 Inflammasome Inhibitor MCC950 in Monocytic Cell Line Confirms Direct MCC950 Engagement with Endogenous NLRP3. ACS Chemical Biology 2024, 19 (4), 962–972.