The Fitzgerald Team utilizes a combination of covalent labelling strategies (e.g., methionine oxidation) and mass spectrometry techniques to investigate the thermodynamic properties of protein folding and ligand binding reactions. Current research efforts involve: (1) the development of new biophysical methods that enable protein folding and stability measurements to be performed on the proteomic scale; and (2) the application of these new methods in areas of disease detection, diagnosis, and drug discovery.

 

 

The Fitzgerald Lab

Aurora and Baiyi prepping for a SPROX experiment!


The Fitzgerald Lab

Quarantined, but still smiling!


The Fitzgerald Lab

Enjoying their new state-of-the-art mass spectrometer!