Category: Biopharmaceutical

Cambridge, MA – Telis Bioscience – Research Associate, Synthetic Biology

Who are we?

We are a growing team of scientists and engineers working to radically accelerate drug development. Our automated antibody design engine is built to safely and effectively drug any novel target in hours instead of months or years. We are looking for teammates who are exceptional at what they do and ready to work hard with a close-knit team to help patients today and prepare for global health threats of the future.

What is this job?

You will be responsible for supporting our high-throughput protein production and purification platform. You will join the Synthesis team to execute automated workflows, perform scaled-down tests of new protocols, and maintain our laboratory hardware. Your role will be a combination of molecular biology, programming, and hardware engineering, weighted according to your background and interests. We encourage applicants from a broad spectrum of science and engineering disciplines, and plan to invest heavily in training you to quickly increase your autonomy and responsibilities. Even if you don’t check every box, but are excited about our mission, please apply!

Who are you?

You have a B.S., M.S., or equivalent experience in a science or engineering field (1+ years of research or industry experience is preferred)

You are familiar with most standard molecular biology workflows, including PCR, plasmid design, cloning, and protein expression and purification

You have previous coding experience or are excited to learn (fluency in Python is preferred)

You are comfortable operating and troubleshooting laboratory hardware (direct experience with liquid handling robots is preferred)

You are trustworthy, passionate, kind, and extremely hardworking

What will you do?

Run day-to-day operation of our automated platform for high-throughput protein production and purification

Test new molecular biology techniques at the bench and adapt them for integration into our automated workflows

Write scripts in our liquid handler control software to execute new protocols

Plan and implement improvements to our standard workflows to optimize throughput, speed, and reliability

Meticulously execute experiments, document laboratory procedures, and analyze, present, and interpret data

We offer competitive salaries, opportunities for rapid advancement, generous stock option packages, comprehensive health/dental/vision coverage, and unlimited paid time off. We come from diverse backgrounds, paths, and lifestyles and commit to equal opportunities for all.

Apply at https://www.telisbio.com/careers/ra

Cambridge, MA – Telis Bioscience – Scientist/Senior Scientist, Antibody Screening

Who are we?

We are a growing team of scientists and engineers working to radically accelerate drug development. Our automated antibody design engine is built to safely and effectively drug any novel target in hours instead of months or years. We are looking for teammates who are exceptional at what they do and ready to work hard with a close-knit team to help patients today and prepare for global health threats of the future.

What is this job?

You will be responsible for using our in-house antibody libraries to rapidly generate diverse binders to a variety of antigens. You will re-invent and optimize established display and screening protocols to improve speed, throughput, and reliability. In addition, you will help automate and scale optimized protocols to conduct hundreds of simultaneous screening experiments. This is a unique position for someone with experience in display technologies who is excited to innovate and push the limits of screening speed and scalability. Even if you don’t check every box, but are excited about our mission, please apply!

Who are you?

You have a Ph.D. or equivalent accomplishments in molecular biology, cell biology, biochemistry, or a related field (2+ years of industry experience in antibody/peptide screening is preferred)

You have a strong track record of designing, implementing, and optimizing screening campaigns using an antibody or peptide display technology (e.g. phage, yeast, bacterial, ribosome or DNA display)

You are comfortable with downstream processing and analysis of screening data (fluency in Python is preferred)

You are excited to innovate to overcome the limitations of established display methods

You are trustworthy, passionate, kind, and extremely hardworking

What will you do?

Plan, develop, and optimize novel, high-throughput assays for protein characterization

Screen Telis antibody libraries against diverse antigens

Critically rethink and optimize every step of the screening process—from library construction to hit identification—with an eye towards unprecedented speed to binder generation

Work with the Automation team to automate and scale up optimized display protocols

Work with the Bioinformatics team to build a deep understanding of screening dynamics through NGS analysis

Meticulously execute experiments, document laboratory procedures, and analyze, present, and interpret data

We offer competitive salaries, opportunities for rapid advancement, generous stock option packages, comprehensive health/dental/vision coverage, and unlimited paid time off. We come from diverse backgrounds, paths, and lifestyles and commit to equal opportunities for all.

Apply at https://www.telisbio.com/careers/scientist-antibody-screening

Cambridge, MA – Telis Bioscience – Scientist/Senior Scientist, Assay Development

Who are we?

We are a growing team of scientists and engineers working to radically accelerate drug development. Our automated antibody design engine is built to safely and effectively drug any novel target in hours instead of months or years. We are looking for teammates who are exceptional at what they do and ready to work hard with a close-knit team to help patients today and prepare for global health threats of the future.

What is this job?

You will be responsible for developing and optimizing biophysical, biochemical, and cell-based assays to analyze our engineered proteins. You will plan, budget, implement, and validate novel assays and lead downstream data collection, analysis, and interpretation. The assays you develop will form a core part of our engineering process and will be integrated into our automated, high-throughput platform. This position is ideal for someone with extensive experience in assay development who is ready to take the speed, throughput, and reliability of antibody characterization to a whole new level. Even if you don’t check every box but are excited about our mission, please apply!

Who are you?

You have a Ph.D. or equivalent accomplishments in biochemistry, biology, biophysics, or a related field (2+ years of industry experience is preferred)

You have a strong track record of designing, implementing, and optimizing assays for protein or peptide characterization (experience with both arrayed and pooled assay formats is preferred)

You are comfortable with mammalian cell-culture and have run cell-based assays using a variety of readouts (e.g. luminescence and fluorescence-based reporters, FRET/BRET, AlphaScreen or AlphaLISA, label-free assays)

You are familiar with common biophysical methods for screening/analyzing protein therapeutics (e.g. SPR, BLI, MST, DSF, DLS, CIC)

You have experience with programmatic processing, analysis, and interpretation of assay data (fluency in Python is preferred)

You are trustworthy, passionate, kind, and extremely hardworking

What will you do?

Plan, develop, and optimize novel, high-throughput assays for protein characterization

Design and execute experiments to validate new assays and overcome limitations of existing approaches

Work closely with the Automation team to integrate new assays into our automation platform

Investigate new techniques to improve the efficiency, throughput, and reliability of our protein characterization workflows

Meticulously execute experiments, document laboratory procedures, and analyze, present, and interpret data

We offer competitive salaries, opportunities for rapid advancement, generous stock option packages, comprehensive health/dental/vision coverage, and unlimited paid time off. We come from diverse backgrounds, paths, and lifestyles and commit to equal opportunities for all.

Apply at https://www.telisbio.com/careers/scientist-assay-development

Durham – BIOMILQ – Computer Science Student Associate

BIOMILQ is developing technology to make breastmilk outside the body, produced from mammary cells. We’re making the future of feeding fearless, and 100% human by offering families a new option for supplemental feeding — one that’s as close to breastmilk as possible and cultivated under safe conditions using our first-of-its-kind technology.

Our provisional patent-pending process leverages the unique biological properties of milk-producing mammary epithelial cells combined with bioreactor technology developed to collect secreted cellular products. The high-density, 3-dimensional system provides similar structural features as the mammary gland, creating the appropriate environment for the cells to reproduce their biological function of milk production, outside of the body. Our process enables us to produce milk that requires no downstream separation, concentration, or intensive thermal processing so we can retain all 2500+ molecules of milk in the perfect constellation for bioavailability and digestibility in infants.

Applications are due April 25, 2021

This position might be for you if:

You are a technical leader

You have conducted experimental research or project design involving at least one or more of the following: coding for life sciences, cell culture, biological and biochemical assays, small-scale engineering design, statistical analysis, literature review

You are comfortable performing critical analyses and interpreting data for actionable decision-making that impacts the greater company

As a life-long learner, you keep a pulse on current relevant scientific literature and innovation within your field

You like to move fast, but are able to maintain meticulous record-keeping

You are a cross-functional powerhouse

You enjoy working closely with teammates to complete deliverables of a caliber to be used in funding applications, investor updates, and publications

You thrive when your input for scientific strategic skills is leveraged, is actively engaging in regular scientific, and broader all-hands team meetings

You have an innate ability to articulate complex topics to a scientific audience as easily as your own family

You love tackling challenging problems with a team

You believe in our mission of working towards better infant nutrition, women’s health, and sustainability

As a conscientious teammate, you’re curious to learn from co-workers and share your personal passions

You enjoy working collaboratively with a broad and diverse team and stepping outside of your comfort zone

You’re naturally inclined to think critically and creatively to work through murky problems with limited resources

Ambiguity is your jam and you’re able to strive ahead without direction

You hold yourself and others to the utmost ethical standards in all scientific and professional endeavors

Qualifications & Preferred Experience

Education
Rising undergraduate senior or graduate student in computer science, statistics, biological or chemical engineering, or another applicable STEM field

Preferred experience with independent hypothesis generation, experimental design, implementation, and analysis
Background knowledge

Required:
Experience creating dashboards or other data trending tools for life sciences
Familiarity with statistical analysis methods and software
Can build us a cloud-based application or Tableau dashboard using data we have generated in the lab along with partnering with our Ph.D. Scientists to help us look at scale-up planning
System controls experience or Computer Science
Experience with cellular biology concepts

Preferred:
Basic understanding of cell-based manufacturing, scale-up and/or bioprocess and bioreactor design considerations

Benefits and Compensation

Preference is given to local students (no relocation assistance provided)
Expected to work 40 hours per week with one week vacation (July 3-11)
Paid summer stipend commensurate to experience
Guaranteed mentorship with C-suite leaders committed to developing your professional skills
Assurance that your contributions support and advance BIOMILQ’s strategic imperatives
Starting with a cohort of student associates with frequent group meetings and experiential learning

For application information, email Michelle.egger@biomilq.com.

Remote – Acidophil – Paid Internship

INTERNS NEEDED IN BIOLOGICAL SCIENCES – Remote

Acidophil is an innovation company that semi-serially creates, manages and co-finances new products and businesses in human health, agriculture, and animal health-based upon biotechnologies that include molecular biology, chemistry and related information technologies. Through our new initiative, Red Abbey Labs, we are focused on addressing Neurological Disorders. For more information please see http://www.acidophil.com.

We are currently seeking bright and talented individuals, with an interest in the commercialization of biotechnology, to work as analysts. Our paid internship program offers a unique opportunity to work at the interface of science and business in an entrepreneurial environment and to experience the process of company formation and development.

The position

• Work for approximately ten to twenty hours a week for a minimum of 3 months
• Perform online research work remotely
• Fully document the research process
• Meet with team members in person or via Skype every week; meetings typically last 1-2 hours

The work

• Generate reports on key technologies/compounds
• Identify and evaluate technical experts from academia and industry
• Endeavor to understand the underlying science of neurobiology projects

The level of responsibility given to the intern will depend on a combination of the interest and ability of the intern and the current demands of the project, which may change over time. The work will be a combination of routine and challenging. The intern must be happy to do either type of work.

Requirements
• Graduate student or post-doc
• Strong background in biology, biochemistry, molecular biology, cell biology, biochemical engineering, bioinformatics, or related field
• Computer literacy (communication is via OneNote/SharePoint and teams, and research is performed online)
• Excellent communication skills (written and oral)
• Time management skills and strong self-motivation

Preferred Qualifications
• Expertise in neurobiology
• Understanding of Neurodegeneration, Neuroinflammation or Immunology (e.g., Alzheimer’s Disease, Dementia)

Application instructions
To apply send a cv and a cover letter describing your experience, why you are interested in the position and what makes you a great fit to Jobs@redabbey.com

Research Triangle Park – CureMint – Part-Time Job

Would you like to work at an early stage startup in a rapidly-changing market? How about one early enough that you’re a central part of the team, and what you do matters, and matters immediately?

CureMint is looking for a part time Data Entry Specialist with potential to grow into a full time role. In this position, you will work directly with our Customer Success Team, Product Development team, and CEO to support positive customer outcomes. This is a part time, entry level position for someone looking to gain experience in a start-up environment.

Experience & Responsibilities

Experience is not a prerequisite as we’re excited to teach an eager, motivated new arrival. However, exceptional communication skills, both written and verbal, next level attention to detail and an appreciation for structure and process are some of the traits we are looking for in an individual. Here are some of the responsibilities you can expect to shoulder:

  • Perform efficient and accurate data entry to support the Customer Success team
  • Re-format vendor provided catalogs into a database compatible format
  • Gather missing information through online research to prepare for data upload
  • Maintain the integrity of a growing product catalog by verifying the accuracy of product SKUs, prices, and other details.
  • Data entry of customer orders in a timely manner

Skills & Qualifications

  • Exceptional time-management skills and ability to maintain both an individual and organizational calendar to monitor and ensure project schedule adherence
  • Familiarity with G suite apps, especially Google Sheets or Excel
  • Comfort with using other online tools for content and process management
  • Excellent focus intently on one project with a willingness to ask questions for clarity
  • Positive attitude

Compensation & Schedule

Hourly rate is dependant on experience.

Schedule is flexible within daytime business hours.

About CureMint

CureMint is a two year old Software as a Service startup company that has recently relocated from Los Angeles, CA to the Triangle area. With angel investment secured from industry leaders, including a leading health care tech accelerator in Nashville, TN, CureMint is disrupting eProcurement, initially within the dental supply chain industry, with a very low-touch, easy-to-use platform.

We are looking for ambitious, conscientious, and hard-working people to come join our team. The application can be found here.

Research Triangle – Metalytics, Inc. – Business Development Internship

Metalytics is a cutting-edge early-stage company combining advanced technologies, software, and services to improve synthetic biology and pharmaceutical biomanufacturing productivity and hence profitability. We provide tools and expertise in the field of metabolic flux analysis (MFA) to measure and understand the dynamics of intracellular nutrient utilization, metabolic efficiency, cell growth and recombinant protein assembly. We are currently seeking an intern to join our business development team to grow our portfolio of industry contacts and customers.

The ideal candidate will be in an MBA or related program, preferably with some experience in the life sciences, and a strong desire to contribute to the growing success of a dynamic company. More specifically, we are seeking an individual who is skilled in navigating company and contact databases, identifying potential leads and prospects using platforms such as LinkedIn and other public sources of company and contact information. This position is home-based and flexible with regard to number of hours required per week. This is an unpaid internship, but presents a valuable opportunity to gain significant business development experience that will enhance your resume, and also may potentially lead to a paid position at some point in the future.

Interested applicants should submit their resume to mark.lombard@metalytics.bio for consideration.