About the Center
The Center for Virology at Duke University Medical Center was founded in January 2002 to provide a focus for research and graduate training in the field of virology.
The Center for Virology currently consists of 24 faculty members from several different departments at Duke. Areas of research interest currently represented within the Center include:
- Structural biology, viral entry, vaccine design (Priyamvada Acharya, PhD)
- Synthetic virology and gene therapy (Aravind Asokan, PhD)
- HBV and genome engineering in humanized mice (Karl-Dimiter Bissig, MD, PhD)
- Viral reservoirs; vaccines and therapeutics development for infectious diseases (Maria Blasi, PhD)
- Virotherapy, Innate immunity in cancer, cancer immunotherapy (Michael Brown, PhD)
- HIV-1 entry and drug development (Chin-Ho Chen, PhD)
- Infections of the GI tract and the maternal-fetal interface (Carolyn Coyne, PhD)
- Role of non-coding RNAs in the regulation of viral replication and pathogenesis (Bryan Cullen, PhD)
- HIV diversity and vaccine development/clinical trials (Thomas Denny, MSc, M.Phil)
Innate immune responses to HIV-1 infection (Guido Ferrari, PhD) - Mechanisms of neurological disease induced by poliovirus and enteroviruses (Matthias Gromeier, PhD)
- Immunotherapeutic interventions, immunity and viral vaccine in cancer (Zachary Hartman, PhD)
- Genetic engineering of negative sense RNA viruses, particularly influenza viruses (Nicholas Heaton, PhD)
- Molecular mechanisms that regulate antiviral innate immunity and virus-host interactions during Flaviviridae virus infection (Stacy Horner, PhD)
- Characterization of innate immune responses to human viral infections, with a specific interest in natural killer (NK) cells (Stephanie Jost, PhD)
- RNA-protein interactions that regulate viral replication (Jack Keene, PhD)
- Pathogenesis and treatment of HIV-1 (Mary Klotman, MD)
- The use of parvovirus-based vectors for the gene therapy of human genetic diseases (Dwight Koeberl, MD, PhD)
- CNS viral infections, Humoral Immunity to Viral infections (Ashley Moseman, PhD)
- The mechanisms of B-cell transformation by Epstein-Barr virus (Micah Luftig, PhD)
- Innate immunity and immunotherapies against viral infections, with a particular focus on nonhuman primate models (Keith Reeves, PhD)
- Viral vaccine design and antibody responses (Kevin Saunders, PhD)
- HIV-1 replication and host responses (Georgia Tomaras, PhD)
- HIV-1 pathogenesis and vaccine development (Kent Weinhold, PhD)
- HIV immunology and clinical vaccine research (Wilton Williams, PhD)