Category Archive: Shared Resources

Mar 16

Pre-Clinical Translational Research Unit

Led by Greg Palmer, PhD, chief director, and Gabi Hanna, MD, executive director, the Duke Pre-clinical Translational Research Unit provides Duke Cancer Institute members the opportunity to perform critical in vivo experiments in a semi-independent laboratory, with input and oversight from experts in cancer biology, statistics, medical device and animal experimentation. “Our goal is to …

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Permanent link to this article: https://sites.duke.edu/dukecancerinstitute/pre-clinical-translational-research-unit/

Feb 16

Shared Resource: Primary Tumor Cell Culture

A developing CCSG Shared Resource, Primary Tumor Cell Culture (PTCC), is creating hundreds of new primary malignant and normal epithelial cell lines. These additional cell lines will provide for novel investigations, including those involving cancer subtypes. “For many cancer researchers, the scarce availability of appropriate model systems for their studies is a significant limitation,” said …

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Permanent link to this article: https://sites.duke.edu/dukecancerinstitute/shared-resource-primary-tumor-cell-culture/

Nov 03

Shared Resource: Information Systems

Led by chief research operations officer Leigh Burgess, MHA, MEd, MA, Duke Cancer Institute Information Systems (DCI-IS) is a shared resource comprised of personnel and sophisticated computer software that process or interpret information to support clinical, translational and basic biomedical research. “Our mission is to provide comprehensive computational support to enable researchers to use technology …

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Permanent link to this article: https://sites.duke.edu/dukecancerinstitute/shared-resource-information-systems/

Oct 13

Shared Resource: Transgenic And Knockout Mouse

Transgenic mice genetically engineered to develop cancer is a relatively new technology first realized during the 1980s. Since that time genetically modified mice have been used extensively in research as models for human disease. Knockout mice lacking tumor suppressing genes make for good models for human cancer. Attesting to the scientific impact of this technology …

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Permanent link to this article: https://sites.duke.edu/dukecancerinstitute/transgenic-and-knockout-mouse-shared-resource/

Sep 08

Shared Resource: Integrative Cancer Genomics

The Integrative Cancer Genomics Shared Resource assembles Duke’s vast genomic technologies, enabling comprehensive consultation, seamless management of complex projects spanning multiple services, enhanced operational flexibility and economies of scale for support services. “About two years ago, Duke Cancer Institute made a decision to merge the Microarray Facility and the Genome Sequencing and Analysis Core Facility …

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Permanent link to this article: https://sites.duke.edu/dukecancerinstitute/shared-resource-integrative-cancer-genomics/

Aug 07

Shared Resource: Behavioral Health and Survey Research Core

Contributed by William Alexander Most of the Duke Cancer Institute’s shared resources offer a glimpse into a smaller world, whether by allowing researchers to better understand the shape of organic compounds, isolate and sort particular cells of interest, or track the growth of tumors in animal models. The Behavioral Health and Survey Research Core (BHSRC) …

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Permanent link to this article: https://sites.duke.edu/dukecancerinstitute/shared-resource-behavioral-health-and-survey-research-core/

Jul 07

Shared Resource: Pharmaceutical Research (Investigational Chemotherapy Service)

The Investigational Chemotherapy Service is one of two labs making up the Pharmaceutical Shared Resource. For information on the PK/PD core labs, click here. Putting a new cancer medication through the early stages of clinical trials is an intimidatingly complex process. A proper dosage regimen must be tailored for every patient. Medications may need to …

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Permanent link to this article: https://sites.duke.edu/dukecancerinstitute/shared-resource-pharmaceutical-research-investigational-chemotherapy-service-2/

Jul 06

Shared Resource: Pharmaceutical Research (PK/PD Core Lab)

Please Note: The PK/PD Core Lab is one of two labs making up the Pharmaceutical Research Shared Resource. Click here to read about the Investigational Chemotherapy Service, the other half of the Shared Resource. Developing a cancer treatment requires understanding two related subjects: pharmacokinetics, or what the body does to a drug, and pharmacodynamics, or …

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Permanent link to this article: https://sites.duke.edu/dukecancerinstitute/shared-resource-pharmaceutical-research-pkpd-core-lab/

Jun 09

Shared Resource: Biospecimen Repository Processing Core

Around the world, volunteers save thousands of lives by donating everything from organs, blood, platelets, and even bone marrow to patients in need. Patients at the Duke Cancer Institute are making their own life-saving impact by making a more unusual donation–cancerous tissue removed during surgical treatment and biopsies. Rather than being transplanted like an organ …

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Permanent link to this article: https://sites.duke.edu/dukecancerinstitute/shared-resource-biospecimen-repository-processing-core/

May 12

Shared Resource: Biostatistics

In many ways, rocket science has nothing on cancer research. Rocket science is firmly based on the reproducible domain of physics. Rockets and fuels can be replicated en masse, and identical rockets will fly the same distance the first time as they do they do the thousandth. But most cancer research takes place in a …

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Permanent link to this article: https://sites.duke.edu/dukecancerinstitute/shared-resource-biostatistics/

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