Svetlana Oukraintseva
I study causes of human aging and related decline in resilience, to identify genetic and other factors responsible for the increase in mortality risk with age eventually limiting longevity. I explores complex relationships, including trade-offs, between physiological aging-changes and risks of major diseases (with emphasis on Alzheimer’s and cancer), as well as survival, to find new genetic and other targets for anti-aging interventions and disease prevention. I also investigate possibilities of repurposing of existing vaccines and treatments for AD prevention and interventions into the aging. For this, my team and I use data from several large human studies containing rich genetic and phenotypic information (including longitudinal measurements) on thousands of individuals. I am a PI and Key Investigator on several NIH funded grants, and has more than 130 peer-reviewed publications, including in major journals such as Nature Reviews, Stroke, European Journal of Human Genetics, and some other.
