August 16, 2022

Delirium in Hospitalized Older Adults – 08/15/2022

NEJM

https://pubmed.ncbi.nlm.nih.gov/?myncbishare=dukemlib&dr=abstract&otool=dukemlib&term=29020579

In the elderly, medications often precipitate delirium. We know withdrawal from alcohol and opioids can do this, but withdrawal from antidepressants also can do this.  These should be tapered gradually to avoid withdrawal or discontinuation syndrome.  Of the SSRI’s, Paxil is the most common culprit. Symptoms can occur 1-7 days after stopping the medication.

08/15/2022