August 16, 2022

Clinical Practice Guideline by the Infectious Diseases Society of America: 2021 Focused Update Guidelines on Management of Clostridium difficile infection in Adults – 08/15/2022

Clinical Infectious Disease

Patients with severe disease (defined as WBC level > 15,000 or cr > 1.5) should ideally be treated with fidaxomicin. Alternatively, oral vancomycin can be used. The antibiotic-associated with causing the infection should ideally be stopped.