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Publications

2021

Chen, Tianyi and Anna Mae Diehl. “A Beautiful Day in the Neighborhood: Application of Single Cell Transcriptomics to Unravel Liver Cell Heterogeneity in Diseased Human Livers.” Journal of Hepatology. 23 March 2021.

2020

Chen, Tianyi, Sehhoon Oh, Simon Gregory, Xiling Shen, and Anna Mae Diehl. “Single-cell omics analysis reveals functional diversification of hepatocytes during liver regeneration.” Jci Insight 5, no. 22 (November 19, 2020). https://doi.org/10.1172/jci.insight.141024.

Loomba, Rohit, Brent A. Neuschwander-Tetri, Arun Sanyal, Naga Chalasani, Anna Mae Diehl, Norah Terrault, Kris Kowdley, et al. “Multicenter Validation of Association Between Decline in MRI-PDFF and Histologic Response in NASH.” Hepatology 72, no. 4 (October 2020): 1219–29. https://doi.org/10.1002/hep.31121.

Hyun, Jeongeun, Zhaoli Sun, Ali Reza Ahmadi, Sushant Bangru, Ullas V. Chembazhi, Kuo Du, Tianyi Chen, et al. “Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis.” J Clin Invest 130, no. 4 (April 1, 2020): 2129–45. https://doi.org/10.1172/JCI132691.

Jewell, Mark L., Jason R. Gibson, Cynthia D. Guy, Jeongeun Hyun, Kuo Du, Seh-Hoon Oh, Richard T. Premont, et al. “Single-Cell RNA Sequencing Identifies Yes-Associated Protein 1-Dependent Hepatic Mesothelial Progenitors in Fibrolamellar Carcinoma.” Am J Pathol 190, no. 1 (January 2020): 93–107. https://doi.org/10.1016/j.ajpath.2019.09.018.

Du, Kuo, Satish K. Chitneni, Ayako Suzuki, Ying Wang, Ricardo Henao, Jeongeun Hyun, Richard T. Premont, et al. “Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression.” Cell Mol Gastroenterol Hepatol 10, no. 1 (2020): 1–21. https://doi.org/10.1016/j.jcmgh.2019.12.006.

2019

Sanyal, Arun J., Stephen A. Harrison, Vlad Ratziu, Manal F. Abdelmalek, Anna Mae Diehl, Stephen Caldwell, Mitchell L. Shiffman, et al. “The Natural History of Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: Data From the Simtuzumab Trials.” Hepatology 70, no. 6 (December 2019): 1913–27. https://doi.org/10.1002/hep.30664.
Diehl, Anna Mae, Nathalie J. Farpour-Lambert, Liping Zhao, and Herbert Tilg. “Why we need to curb the emerging worldwide epidemic of nonalcoholic fatty liver disease.” Nat Metab 1, no. 11 (November 2019): 1027–29. https://doi.org/10.1038/s42255-019-0140-x.
Hyun, Jeongeun, Seh-Hoon Oh, Richard T. Premont, Cynthia D. Guy, Carl L. Berg, and Anna Mae Diehl. “Dysregulated activation of fetal liver programme in acute liver failure.” Gut 68, no. 6 (June 2019): 1076–87. https://doi.org/10.1136/gutjnl-2018-317603.