This conversation was led by Anne-Ruxandra Carvunis, Associate Professor in Computational & Systems Biology at the University of Pittsburgh School of Medicine.
What makes each species unique? Dr. Carvunis discussed how thousands of small species-specific proteins contribute to molecular innovation in eukaryotes and the potential implications for human physiology in health and disease.
- Carvunis et al., 2012, “Proto-genes and de novo gene birth” (doi:10.1038/nature11184)
- Keeling et al., 2019, “The meanings of ‘function’ in biology and the problematic case of de novo gene emergence” (doi:10.754/eLife.47014.001)
- Mudge et al., 2022, “Standardized annotation of translated open reading frames” (doi:10.1038/s41587-022-01369-0).
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