The next seminar in the Immunology for Quants series will be on January 23rd, 2020 and presented by Cliburn Chan. The seminar will be held at Hock Plaza in classroom 11100 between noon and 1pm.
Unlike antibodies, T cells can “look” inside proteins and inside cells, and this is essential for defense against intracellular pathogens and tumors. This seminar reviews how T cells achieve this feat, looking at T cell activation in terms of 1) the TCR – peptide: MHC interaction, 2) signal transduction via the CD3 complex and the role of the CD4/CD8 co-receptor, 3) downstream pathways that affect transcription, metabolism, cytoskeleton and formation of the immune synapse, and 4) co-stimulation and co-inhibition molecules that regulate T cell activation.
The Immunology for Quants talks are biweekly, informal seminars that are designed to introduce immunology and immune-related diseases to non-immunologists. Topics are generally self-contained and questions during the seminar are encouraged, so it is not strictly necessary (but recommended) to attend them in sequence. Seminars are held on Thursdays from 12-1 pm.