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Search Results for: Duke Family Support Program
JOURNAL ARTICLES, BOOKS, AND BOOK CHAPTERS PUBLISHED
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Belsky DW, Harrati A. To the freezers! Stored biospecimens from human randomized trials are an important new direction for studies of biological aging. J Gerontol A Biol Sci Med Sci. 2019 Jan 1;74(1):89-90. [Institutional access] [PubMed]
Berger M, Oyeyemi D, Olurinde MO, Whitson HE, Weinhold KJ, Woldorff MG, Lipsitz LA, Moretti E, Giattino CM, Roberts KC, Zhou J, Bunning T, Ferrandino M, Scheri RP, Cooter M, Chan C, Cabeza R, Browndyke JN, Murdoch DM, Devinney MJ, Shaw LM, Cohen HJ, Mathew JP; and the INTUIT Investigators. The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction. J Am Geriatr Soc. 2019 Apr;67(4):794-798. [Institutional access] [PubMed]
Bowling CB, Whitson HE, Johnson TM 2nd. The 5Ts: Preliminary Development of a Framework to Support Inclusion of Older Adults in Research. J Am Geriatr Soc. 2019 Feb;67(2):342-346. [Institutional access] [PubMed]
McKellar MS, Kuchibhatla MN, Oursler KK, Crystal S, Akgün KM, Crothers K, Gibert CL, Nieves-Lugo K, Womack J, Tate JP, Fillenbaum, GG. Race differences in change in physical functioning in older male veterans with HIV. AIDS Research and Human Retroviruses, Accepted 2019.
Allen JD, Vanbruggen MD, Johannsen NM, Robbins JL, Credeur DP, Pieper CF, Sloane R, Earnest CP, Church TS, Ravussin E, Kraus WE, Welsch MA. PRIME: A Novel Low-Mass, High-Repetition Approach to Improve Function in Older Adults. Med Sci Sports Exerc. 2018 May;50(5):1005-1014. [Institutional access] [PMC free article] [PubMed]
Belsky DW, Moffitt TE, Cohen AA, Corcoran DL, Levine ME, Prinz JA, Schaefer J, Sugden K, Williams B, Poulton R, Caspi A. Eleven Telomere, Epigenetic Clock, and Biomarker-Composite Quantifications of Biological Aging: Do They Measure the Same Thing? Am J Epidemiol. 2018 Jun 1;187(6):1220-1230. [Institutional access] [PMC free article-Available 06/01/2019] [PubMed]
Berger M, Schenning KJ, Brown CH 4th, et al. Best Practices for Postoperative Brain Health: Recommendations From the Fifth International Perioperative Neurotoxicity Working Group. Anesth Analg. 2018 Dec;127(6):1406-1413. [Institutional access] [PubMed]
Blay SL, Fillenbaum GG, Mello MF, Quintana MI, Mari JJ, Bressan RA, Andreoli SB. 12-month prevalence and concomitants of DSM-IV depression and anxiety disorders in two violence-prone cities in Brazil. J Affect Disord. 2018 May;232:204-211. [Institutional access] [PMC free article] [PubMed]
Brinkley TE, Berger MS, Callahan KE, Fieo RA, Jennings LA, Morris JK, Wilkins HM, Kritchevsky SB. Workshop on Synergies Between Alzheimer’s Research and Clinical Gerontology and Geriatrics: Current Status and Future Directions. J Gerontol A Biol Sci Med Sci 2018 Corrected proof. [Institutional access]
Cary MP Jr, Goode V, Crego N, Thornlow D, Colón-Emeric CS, Hoenig HM, Baba K, Fellingham S, Merwin EI. Hospital Readmission in Total Hip Replacement Patients in 2009 and 2014. Arch Phys Med Rehabil. 2018 Jun;99(6):1213-1216. [Institutional access] [PMC free article-Available 06/01/2019] [PubMed]
Cary MP Jr, Hall RK, Anderson AL, Burd A, McConnell ES, Anderson RA, Colón-Emeric CS. Management Team Perceptions of Risks and Strategies for Preventing Falls Among Short-Stay Patients in Nursing Homes. Health Care Manag (Frederick). 2018 Jan/Mar;37(1):76-85. [Institutional access] [PMC free article] [PubMed]
Chan VTT, Sun Z, Tang S, Chen LJ, Wong A, Tham CC, Wong TY, Chen C, Ikram MK, Whitson HE, Lad EM, Mok VCT, Cheung CY. Spectral-Domain OCT Measurements in Alzheimer’s Disease: A Systematic Review and Meta-analysis. Ophthalmology. 2018 Aug 13. pii: S0161-6420(18)30258-6. [Institutional access] [PubMed]
Chou CH, Attarian DE, Wisniewski HG, Band PA, Kraus VB. TSG-6 – a double-edged sword for osteoarthritis (OA). Osteoarthritis Cartilage. 2018 Feb;26(2):245-254. [Institutional access] [PMC free article] [PubMed]
Colón-Emeric CS, Corazzini KN, McConnell ES, Pan W, Toles MP, Hall R, Batchelor-Murphy M, Yap TL, Anderson AL, Burd A, Amarasekara S, Anderson RA. Resident Vignettes for Assessing Care Quality in Nursing Homes. J Am Med Dir Assoc. 2017 Nov 21 e-pub. [Institutional access] [PMC free article] [PubMed]
Colón-Emeric CS, Pieper CF, Van Houtven CH, Grubber JM, Lyles KW, Lafleur J, Adler RA. Limited Osteoporosis Screening Effectiveness Due to Low Treatment Rates in a National Sample of Older Men. Mayo Clin Proc. 2018 Dec;93(12):1749-1759. [Institutional access] [PMC free article-Available 12/01/2019] [PubMed]
Cooper C, Gross A, Brinkman C, Pope R, Allen K, Hastings S, Bogen BE, Goode AP. The impact of wearable motion sensing technology on physical activity in older adults. Exp Gerontol. 2018 Oct 2;112:9-19. [Institutional access] [PubMed]
Domingue BW, Belsky DW, Fletcher JM, Conley D, Boardman JD, Harris KM. The social genome of friends and schoolmates in the National Longitudinal Study of Adolescent to Adult Health. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):702-707. [Institutional access] [PMC free article] [PubMed]
Doshi A., Cabeza R., Berger M. (2018) Geriatric Anesthesia: Age-Dependent Changes in the Central and Peripheral Nervous Systems. In: Reves J., Barnett S., McSwain J., Rooke G. (eds) Geriatric Anesthesiology. Springer, Cham. [Publisher link]
Duan-Porter W, Hatch D, Pendergast JF, Freude G, Rose U, Burr H, Müller G, Martus P, Pohrt A, Potter G. 12-month trajectories of depressive symptoms among nurses-Contribution of personality, job characteristics, coping, and burnout. J Affect Disord. 2018 Jul;234:67-73. [Institutional access] [PMC free article] [PubMed]
Furman BD, Kent CL, Huebner JL, Kraus VB, McNulty AL, Guilak F, Olson SA. CXCL10 is upregulated in synovium and cartilage following articular fracture. J Orthop Res. 2018 Apr;36(4):1220-1227. [Institutional access] [PMC free article] [PubMed]
Garg T, Anzuoni K, Landyn V, Hajduk A, Waring S, Hanson LR, Whitson HE. The AGING Initiative experience: a call for sustained support for team science networks. Health Res Policy Syst. 2018 May 18;16(1):41. [Institutional access] [PMC free article] [PubMed]
Gray SL, Hart LA, Perera S, Semla TP, Schmader KE, Hanlon JT. Meta-analysis of Interventions to Reduce Adverse Drug Reactions in Older Adults. J Am Geriatr Soc. 2018 Feb;66(2):282-288. [Institutional access] [PMC free article] [PubMed]
Gray SL, Marcum ZA, Schmader KE, Hanlon JT. Update on Medication Use Quality and Safety in Older Adults, 2017. J Am Geriatr Soc. 2018 Dec;66(12):2254-2258. [Institutional access] [PMC free article] [PubMed]
Hall KS, Morey MC, Beckham JC, Bosworth HB, Pebole MM, Pieper CF, Sloane R. The Warrior Wellness Study: A Randomized Controlled Exercise Trial for Older Veterans with PTSD. Transl J Am Coll Sports Med. 2018 Mar 15;3(6):43-51. [Institutional access] [PMC free article] [PubMed]
Hall RK, Luciano A, Pieper C, Colón-Emeric CS. Association of Kidney Disease Quality of Life (KDQOL-36) with mortality and hospitalization in older adults receiving hemodialysis. BMC Nephrol. 2018 Jan 15;19(1):11. [Institutional access] [PMC free article] [PubMed]
Hall RK, Sloane R, Pieper C, Van Houtven C, LaFleur J, Adler R, Colón-Emeric C. Competing Risks of Fracture and Death in Older Adults with Chronic Kidney Disease. J Am Geriatr Soc. 2018 Mar;66(3):532-538. [Institutional access] [PMC free article] [PubMed]
Hobson-Webb LD, Zwelling PJ, Pifer AN, Killelea CM, Faherty MS, Sell TC, Pastva AM. Point of Care Quantitative Assessment of Muscle Health in Older Individuals: An Investigation of Quantitative Muscle Ultrasound and Electrical Impedance Myography Techniques. Geriatrics 2018, 3(4), 92. [Open access]
Hughes, JM, Ulmer, CS, Hastings, SN, Gierisch, JM, Mid-Atlantic VA MIRECC Workgroup, and Howard, MO. Sleep, resilience, and psychological distress in United States military Veterans. Military Psychology. 2018 Sept 3;30(5): 404-414. [Journal link]
Huynh FK, Hu X, Lin Z, Johnson JD, Hirschey MD. Loss of sirtuin 4 leads to elevated glucose- and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds. J Inherit Metab Dis. 2018 Jan;41(1):59-72. [Institutional access] [PMC free article] [PubMed]
Lee RH, Sloane R, Pieper C, Lyles KW, Adler RA, Van Houtven C, LaFleur J, Colón-Emeric C. Clinical Fractures Among Older Men With Diabetes Are Mediated by Diabetic Complications. J Clin Endocrinol Metab. 2018 Jan 1;103(1):281-287. [Institutional access] [PMC free article] [PubMed]
Longobardi L, Jordan JM, Shi XA, Renner JB, Schwartz TA, Nelson AE, Barrow DA, Kraus VB, Spagnoli A. Associations between the chemokine biomarker CCL2 and knee osteoarthritis outcomes: the Johnston County Osteoarthritis Project. Osteoarthritis Cartilage. 2018 Sep;26(9):1257-1261. [Institutional access] [PMC free article-Available 09/01/2019] [PubMed]
Lv Y-B, Gao X, Yin ZX, Chen HS, Luo JS, Brasher MS, Kraus VB, Li TT, Zeng Y, Shi XM. Revisiting the association of blood pressure with mortality in oldest old people in China: community based, longitudinal prospective study. BMJ. 2018 Jun 5;361:k2158. doi: 10.1136/bmj.k2158. [Journal access] [PMC free article] [PubMed]
Lv Y-B, Liu S, Yin Z-X, Gao X, Kraus VB, Mao C, Yuan J-Q, Zhang J, Luo J-S, Chen H-S, Zeng Y, Shi X-M. Associations of Body Mass Index and Waist Circumference with 3-Year All-Cause Mortality Among the Oldest Old: Evidence from a Chinese Community-Based Prospective Cohort Study. J Am Med Dir Assoc. 2018 Aug;19(8):672-678.e4. [Institutional access] [PubMed]
McAdams-DeMarco MA, Olorundare IO, Ying H, Warsame F, Haugen CE, Hall R, Garonzik-Wang JM, Desai NM, Walston JD, Norman SP, Segev DL. Frailty and Postkidney Transplant Health-Related Quality of Life. Transplantation. 2018 Feb;102(2):291-299. [Institutional access] [PMC free article] [PubMed]
Morey MC, Lee CC, Castle S, Valencia WM, Katzel L, Giffuni J, Kopp T, Cammarata H, McDonald M, Oursler KA, Wamsley T, Jain C, Bettger JP, Pearson M, Manning KM, Intrator O, Veazie P, Sloane R, Li J, Parker DC. Should Structured Exercise Be Promoted As a Model of Care? Dissemination of the Department of Veterans Affairs Gerofit Program. J Am Geriatr Soc. 2018 May;66(5):1009-1016. [Institutional access] [PMC free article] [PubMed]
Noppert GA, Brown CS, Chanti-Ketterl M, Hall KS, Newby LK, Cohen HJ, Morey MC. The Impact of Multiple Dimensions of Socioeconomic Status on Physical Functioning Across the Life Course. Gerontol Ger Med. 2018 Aug. [Free Journal access]
Pastva AM, Duncan PW, Reeves GR, Nelson MB, Whellan DJ, O’Connor CM, Eggebeen JD, Hewston LA, Taylor KM, Mentz RJ, Rosenberg PB, Kitzman DW. Strategies for supporting intervention fidelity in the rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial. Contemp Clin Trials. 2018 Jan;64:118-127. [Institutional access] [PMC free article] [PubMed]
Pastva AM, Walker JKL. Commentary: Central-acting therapeutics alleviate respiratory weakness caused by heart failure-induced ventilatory overdrive. Front Physiol. 2018 May 23;9:554. [Institutional access] [PMC free article] [PubMed]
Pavon JM, Sloane RJ, Pieper CF, Colón-Emeric CS, Cohen HJ, Gallagher D, Morey MC, McCarty M, Ortel TL, Hastings SN. Automated versus Manual Data Extraction of the Padua Prediction Score for Venous Thromboembolism Risk in Hospitalized Older Adults. Appl Clin Inform. 2018 Jul;9(3):743-751. [Institutional access] [PMC free article-Available 07/01/2019] [PubMed]
Pavon JM, Sloane RJ, Pieper CF, Colón-Emeric CS, Cohen HJ, Gallagher D, Morey MC, McCarty M, Ortel TL, Hastings SN. Poor Adherence to Risk Stratification Guidelines Results in Overuse of Venous Thromboembolism Prophylaxis in Hospitalized Older Adults. J Hosp Med. 2018 Jun 1;13(6):403-404. [Institutional access] [PMC free article] [PubMed]
Safeek RH, Hall KS, Lobelo F, Del Rio C, Khoury AL, Wong T, Morey MC, McKellar MS. Low Levels of Physical Activity Among Older Persons Living with HIV/AIDS Are Associated with Poor Physical Function. AIDS Res Hum Retroviruses. 2018 Nov;34(11):929-935. [Institutional access] [PubMed]
Warsame F, Haugen CE, Ying H, Garonzik-Wang JM, Desai NM, Hall RK, Kambhampati R, Crews DC, Purnell TS, Segev DL, McAdams-DeMarco MA. Limited health literacy and adverse outcomes among kidney transplant candidates. Am J Transplant. 2018 Jul 1. [Institutional access] [PubMed]
White JP, Billin AN, Campbell ME, Russell AJ, Huffman KM, Kraus WE. The AMPK/p27Kip1 Axis Regulates Autophagy/Apoptosis Decisions in Aged Skeletal Muscle Stem Cells. Stem Cell Reports. 2018 Aug 14;11(2):425-439. [Journal access] [PMC free article] [PubMed]
Whitson HE, Cohen HJ, Schmader KE, Morey MC, Kuchel G, Colon-Emeric CS. Physical Resilience: Not Simply the Opposite of Frailty. J Am Geriatr Soc. 2018 Mar 25. [Institutional access] [PMC free article-Available 08/01/2019] [PubMed]
Whitson HE, Cronin-Golomb A, Cruickshanks KJ, Gilmore GC, Owsley C, Peelle JE, Recanzone G, Sharma A, Swenor B, Yaffe K, Lin FR. American Geriatrics Society and National Institute on Aging Bench-to-Bedside Conference: Sensory Impairment and Cognitive Decline in Older Adults. J Am Geriatr Soc. 2018 Nov;66(11):2052-2058. [Institutional access] [PubMed]
Whitson HE, Potter GG, Feld JA, Plassman BL, Reynolds K, Sloane R, Welsh-Bohmer KA. Dual-Task Gait and Alzheimer’s Disease Genetic Risk in Cognitively Normal Adults: A Pilot Study.J Alzheimers Dis. 2018;64(4):1137-1148. [Institutional access] [PubMed]
Yuan JQ, Lv YB, Chen HS, Gao X, Yin ZX, Wang WT, Kraus VB, Luo JS, Wang JN, Zeng Y, Mao C, Shi XM. Association Between Late-Life Blood Pressure and the Incidence of Cognitive Impairment: A Community-Based Prospective Cohort Study. J Am Med Dir Assoc. 2018 Jul 13. pii: S1525-8610(18)30301-3. [Institutional access] [PubMed]
Zuo X, Luciano A, Pieper CF, Bain JR, Kraus VB, Kraus WE, Morey MC, Cohen HJ. Combined Inflammation and Metabolism Biomarker Indices of Robust and Impaired Physical Function in Older Adults. J Am Geriatr Soc. 2018 Jul;66(7):1353-1359. [Institutional access] [PubMed]
AbouAssi H, Connelly MA, Bateman LA, Tune KN, Huebner JL, Kraus VB, Winegar DA, Otvos JD, Kraus WE, Huffman KM. Does a lack of physical activity explain the rheumatoid arthritis lipid profile? Lipids Health Dis. 2017 Feb 10;16(1):39. [PMC free article] [PubMed]
Anderson KA, Madsen AS, Olsen CA, Hirschey MD. Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio. Biochim Biophys Acta. 2017 Dec;1858(12):991-998. [Institutional access] [PMC free article] [PubMed]
Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD. SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion. Cell Metab. 2017 Apr 4;25(4):838-855.e15. [Institutional access] [PMC free article] [PubMed]
Batchelor-Murphy MK, McConnell ES, Amella EJ, Anderson RA, Bales CW, Silva S, Barnes A, Beck C, Colon-Emeric CS. Experimental Comparison of Efficacy for Three Handfeeding Techniques in Dementia. J Am Geriatr Soc. 2017 Apr;65(4):e89-e94. [Institutional access] [PMC free article] [PubMed]
Belsky DW, Caspi A, Cohen HJ, Kraus WE, Ramrakha S, Poulton R, Moffitt TE. Impact of early personal-history characteristics on the Pace of Aging: implications for clinical trials of therapies to slow aging and extend healthspan. Aging Cell. 2017 Apr 12. [Institutional access] [PubMed]
Belsky DW, Huffman KM, Pieper CF, Shalev I, Kraus WE. Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis. J Gerontol A Biol Sci Med Sci. 2017 Dec 12;73(1):4-10. [Institutional access] [PMC free article] [PubMed]
Belsky DW, Snyder-Mackler N. Invited Commentary: Integrating Genomics and Social Epidemiology-Analysis of Late-Life Low Socioeconomic Status and the Conserved Transcriptional Response to Adversity. Am J Epidemiol. 2017 Sep 1;186(5):510-513. [Institutional access] [PMC free article] [PubMed]
Berger M, Ponnusamy V, Greene N, Cooter M, Nadler JW, Friedman A, McDonagh DL, Laskowitz DT, Newman MF, Shaw LM, Warner DS, Mathew JP, James ML; MAD-PIA Investigators. The Effect of Propofol vs. Isoflurane Anesthesia on Postoperative Changes in Cerebrospinal Fluid Cytokine Levels: Results from a Randomized Trial. Front Immunol. 2017 Nov 13;8:1528. [Institutional access] [PMC free article] [PubMed]
Burke TW, Henao R, Soderblom E, Tsalik EL, Thompson JW, McClain MT, Nichols M, Nicholson BP, Veldman T, Lucas JE, Moseley MA, Turner RB, Lambkin-Williams R, Hero AO 3rd, Woods CW, Ginsburg GS Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection. EBioMedicine. 2017 Mar;17:172-181. [PMC free article] [PubMed]
Colón-Emeric CS, Corazzini K, McConnell ES, Pan W, Toles M, Hall R, Cary MP Jr, Batchelor-Murphy M, Yap T, Anderson AL, Burd A, Amarasekara S, Anderson RA. Effect of Promoting High-Quality Staff Interactions on Fall Prevention in Nursing Homes: A Cluster-Randomized Trial. JAMA Intern Med. 2017 Nov 1;177(11):1634-1641. [Institutional access] [PMC free article] [PubMed]
Colón-Emeric CS, Corazzini K, McConnell E, Pan W, Toles M, Hall R, Batchelor-Murphy M, Yap TL, Anderson AL, Burd A, Anderson RA. Study of Individualization and Bias in Nursing Home Fall Prevention Practices. J Am Geriatr Soc. 2017 Apr;65(4):815-821. Minority Research Publication [Institutional access] [PMC free article] [PubMed]
Conroy DE, Wolin KY, Blair CK, Demark-Wahnefried W. Gender-varying associations between physical activity intensity and mental quality of life in older cancer survivors. Support Care Cancer. 2017 Nov;25(11):3465-3473. [Institutional access] [PMC free article] [PubMed]
Cowper PA, Peterson MJ, Pieper CF, Sloane RJ, Hall KS, McConnell ES, Bosworth HB, Ekelund CC, Pearson MP, Morey MC. Economic Analysis of Primary Care-Based Physical Activity Counseling in Older Men: The VA-LIFE Trial. J Am Geriatr Soc. 2017 Mar;65(3):533-539. [Institutional access] [PMC free article] [PubMed]
Daghestani HN, Jordan JM, Renner JB, Doherty M, Wilson AG, Kraus VB. Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden. PLoS One. 2017 Dec 29;12(12):e0190251. [Institutional access] [PMC free article] [PubMed]
Deveza LA, Kraus VB, Collins JE, Guermazi A, Roemer FW, Bowes M, Nevitt MC, Ladel C, Hunter DJ. Association Between Biochemical Markers of Bone Turnover and Bone Changes on Imaging: Data From the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2017 Aug;69(8):1179-1191. [Institutional access] [PMC free article] [PubMed]
Domingue BW, Liu H, Okbay A, Belsky DW. Genetic Heterogeneity in Depressive Symptoms Following the Death of a Spouse: Polygenic Score Analysis of the U.S. Health and Retirement Study. Am J Psychiatry. 2017 Mar 24:appiajp201716111209. [Institutional access] [PubMed]
Domingue BW, Belsky DW, Harrati A, Conley D, Weir DR, Boardman JD. Mortality selection in a genetic sample and implications for association studies. Int J Epidemiol. 2017 Apr 11. [Institutional access] [PubMed]
Goode AP, Nelson AE, Kraus VB, Renner JB, Jordan JM. Biomarkers reflect differences in osteoarthritis phenotypes of the lumbar spine: the Johnston County Osteoarthritis Project. Osteoarthritis Cartilage. 2017 Oct;25(10):1672-1679. Minority Research Publication [Institutional access] [PMC free article] [PubMed]
Hall KS, Cohen HJ, Pieper CF, Fillenbaum GG, Kraus WE, Huffman KM, Cornish M, Shiloh A, Flynn C, Sloane R, Newby LK, Morey MC. Physical performance across the adult lifespan: correlates with age and physical activity. J Gerontol A Biol Sci Med Sci 2017 Apr;72(4):572-578. [Institutional access] [PubMed]
Hall RK. Reply to: Comment on: “Incorporating Geriatric Assessment into a Nephrology Clinic: Preliminary Data from Two Models of Care”. J Am Geriatr Soc. 2017 Apr;65(4):880. [Institutional access] [PMC free article] [PubMed]
Hall RK, Myers ER, Rosas SE, O’Hare AM, Colón-Emeric CS. Choice of Hemodialysis Access in Older Adults: A Cost-Effectiveness Analysis. Clin J Am Soc Nephrol. 2017 Jun 7;12(6):947-954. [Institutional access] [PMC free article] [PubMed]
Hastings WJ, Shalev I, Belsky DW. Translating Measures of Biological Aging to Test Effectiveness of Geroprotective Interventions: What Can We Learn from Research on Telomeres? Front Genet. 2017 Nov 22;8:164. [Institutional access] [PMC free article] [PubMed]
Hatcher CC, Collins AT, Kim SY, Michel LC, Mostertz WC 3rd, Ziemian SN, Spritzer CE, Guilak F, DeFrate LE, McNulty AL. Relationship between T1rho magnetic resonance imaging, synovial fluid biomarkers, and the biochemical and biomechanical properties of cartilage. J Biomech. 2017 Apr 11;55:18-26. [Institutional access] [PMC free article] [PubMed]
Holcomb ZE, Tsalik EL, Woods CW, McClain MT. Host-Based Peripheral Blood Gene Expression Analysis for Diagnosis of Infectious Diseases. J Clin Microbiol. 2017 Feb;55(2):360-368. [Institutional access] [PMC free article] [PubMed]
Huffman KM, Jessee R, Andonian B, Davis BN, Narowski R, Huebner JL, Kraus VB, McCracken J, Gilmore BF, Tune KN, Campbell M, Koves TR, Muoio DM, Hubal MJ, Kraus WE. Molecular alterations in skeletal muscle in rheumatoid arthritis are related to disease activity, physical inactivity, and disability. Arthritis Res Ther. 2017 Jan 23;19(1):12. [PMC free article] [PubMed]
Hurria A, High KP, Mody L, McFarland Horne F, Escobedo M, Halter J, Hazzard W, Schmader K, Klepin H, Lee S, Makris UE, Rich MW, Rogers S, Wiggins J, Watman R, Choi J, Lundebjerg N, Zieman S. Aging, the Medical Subspecialties, and Career Development: Where We Were, Where We Are Going. J Am Geriatr Soc. 2017 Apr;65(4):680-687. [Institutional access] [PubMed]
Kanach FA, Pastva A, Hall KS, Pavon JM, Morey MC. Effects of Structured Exercise Interventions for Older Adults Hospitalized with Acute Medical Illness: A Systematic Review. J Aging Phys Act. Epub 2017 Jun 12. [Institutional access] [PubMed]
King KE, Fillenbaum GG, Cohen HJ. A Cumulative Deficit Laboratory Test–based Frailty Index: Personal and Neighborhood Associations. J Am Geriatr Soc. Epub 2017 Jun 30. Minority Research Publication [Institutional access] [PubMed]
Lv YB, Zhu PF, Yin ZX, Kraus VB, Threapleton D, Chei CL, Brasher MS, Zhang J, Qian HZ, Mao C, Matchar DB, Luo JS, Zeng Y, Shi XM. A U-shaped Association Between Blood Pressure and Cognitive Impairment in Chinese Elderly. J Am Med Dir Assoc. 2017 Feb 1;18(2):193.e7-193.e13. [Institutional access] [PMC free article] [PubMed]
Mewshaw J, Bailey DE Jr, Anderson AL, Anderson RA, Burd AL, Colón-Emeric C, Corazzini KN. A novel program for ABSN students to generate interest in geriatrics and geriatric nursing research. J Nurs Educ Pract. 2017;7(6):95-99. [PMC free article] [PubMed]
Miller JM, Sabol VK, Pastva AM. Promoting older adult physical activity throughout care transitions using an interprofessional approach. J Nurse Pract. 2017;13(1):64-71. [Institutional access]
Moffitt TE, Belsky DW, Danese A, Poulton R, Caspi A. The Longitudinal Study of Aging in Human Young Adults: Knowledge Gaps and Research Agenda. J Gerontol A Biol Sci Med Sci. 2017 Feb;72(2):210-215. [Institutional access] [PMC free article] [PubMed]
Pastva AM, Duncan PW, Reeves GR, Patel M, Nelson MB, Whellan DJ, O’Conner CM, Eggebeen JD, Hewston LA, Taylor K, Mentz RJ, Rosenberg PB, Kitzman DW. Strategies for supporting intervention fidelity in the Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial. Contemp Clin Trials, 2017;Nov 6. [Institutional access] [PubMed]
Pavon JM, Sloane R, Morey MC, Hastings SN. Inpatient Mobility Measures As Useful Predictors of Discharge Destination in Hospitalized Older Adults. J Am Geriatr Soc. 2017 Jan;65(1):224-226. [Institutional access] [PubMed]
Reeves GR, Whellan DJ, Duncan P, O’Connor CM, Pastva AM, Eggebeen JD, Hewston LA, Morgan TM, Reed SD, Rejeski WJ, Mentz RJ, Rosenberg PB, Kitzman DW; REHAB-HF Trial Investigators. Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial: Design and rationale. Am Heart J. 2017 Mar;185:130-139. [Institutional access] [PMC free article] [PubMed]
Richmond-Rakerd LS, Belsky DW. Swedish Register Analysis of Divorce and Alcohol Use Disorder Highlights Social Relationships as a Target for Preventive Psychiatry and Genetic Research. Am J Psychiatry. 2017 May 1;174(5):411-413. [Institutional access] [PubMed]
Schaefer JD, Caspi A, Belsky DW, Harrington H, Houts R, Horwood LJ, Hussong A, Ramrakha S, Poulton R, Moffitt TE. Enduring mental health: Prevalence and prediction. J Abnorm Psychol. 2017 Feb;126(2):212-224. [PMC free article] [PubMed]
Schaefer JD, Scult MA, Caspi A, Arseneault L, Belsky DW, Hariri AR, Harrington H, Houts R, Ramrakha S, Poulton R, Moffitt TE. Is low cognitive functioning a predictor or consequence of major depressive disorder? A test in two longitudinal birth cohorts. Dev Psychopathol. 2017 Nov 16:1-15. [Institutional access] [PubMed]
Serra MC, Addison O, Giffuni J, Paden L, Morey MC, Katzel L. Physical Function Does Not Predict Care Assessment Need Score in Older Veterans. J Appl Gerontol. 2017 Jan 1:733464817690677. [Institutional access] [PubMed]
Sobel Leonard A, McClain MT, Smith GJ, Wentworth DE, Halpin RA, Lin X, Ransier A, Stockwell TB, Das SR, Gilbert AS, Lambkin-Williams R, Ginsburg GS, Woods CW, Koelle K, Illingworth CJ. The effective rate of influenza reassortment is limited during human infection. PLoS Pathog. 2017 Feb 7;13(2):e1006203. [PMC free article] [PubMed]
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Blay SL, Fillenbaum GG, Pitta JC, Peluso ET. Factors associated with antidepressant, anxiolytic, and other psychotropic medication use to treat psychiatric symptoms in the city of São Paulo, Brazil. Int Clin Psychopharmacol. 2014 May;29(3):157-165. [PMC free article] [PubMed]
Clark N, Fan VS, Slatore CG, Locke E, Whitson HE, Nici L, Thielke SM. Dyspnea and pain frequently co-occur among Medicare managed care recipients. Ann Am Thorac Soc. 2014 Jul;11(6):890-897. [PMC free article] [PubMed]
Hastings SN, Sloane R, Morey MC, Pavon JM, Hoenig H. Assisted early mobility for hospitalized older veterans: preliminary data from the STRIDE program. J Am Geriatr Soc. 2014 Nov;62(11):2180-2184. [PMC free article] [PubMed]
Herati RS, Reuter MA, Dolfi DV, Mansfield KD, Aung H, Badwan OZ, Kurupati RK, Kannan S, Ertl H, Schmader KE, Betts MR, Canaday DH, Wherry EJ. Circulating CXCR5+PD-1+ response predicts influenza vaccine antibody responses in young adults but not elderly adults. J Immunol. 2014 Oct 1;193(7):3528-3537. [PMC free article] [PubMed]
Huffman KM, Koves TR, Hubal MJ, Abouassi H, Beri N, Bateman LA, Stevens RD, Ilkayeva OR, Hoffman EP, Muoio DM, Kraus WE. Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness. Diabetologia. 2014 Nov;57(11):2282-2295. [PMC free article] [PubMed]
Hunter DJ, Nevitt M, Losina E, Kraus V. Biomarkers for osteoarthritis: current position and steps towards further validation. Best Pract Res Clin Rheumatol. 2014 Feb;28(1):61-71. [PMC free article] [PubMed]
Hsueh MF, Önnerfjord P, Kraus VB. Biomarkers and proteomic analysis of osteoarthritis. Matrix Biol. 2014 Oct;39:56-66. [PubMed]
Hybels CF, George LK, Blazer DG, Pieper CF, Cohen HJ, Koenig HG. Inflammation and Coagulation as Mediators in the Relationships Between Religious Attendance and Functional Limitations in Older Adults. J Aging Health. 2014 Jun 26(4):679-697. [PMC free article] [PubMed]
Israel S, Caspi A, Belsky DW, Harrington H, Hogan S, Houts R, Ramrakha S, Sanders S, Poulton R, Moffitt TE. Credit scores, cardiovascular disease risk, and human capital. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17087-17092. [PMC free article] [PubMed]
Itty S, Day S, Lyles KW, Stinnett SS, Vajzovic LM, Mruthyunjaya P. Vitamin D deficiency in neovascular versus nonneovascular age-related macular degeneration. Retina. 2014 Sep;34(9):1779-1786. [PMC free article] [PubMed]
Kitzman DW, Nicklas B, Kraus WE, Lyles MF, Eggebeen J, Morgan TM, Haykowsky M. Skeletal muscle abnormalities and exercise intolerance in older patients with heart failure and preserved ejection fraction. Am J Physiol Heart Circ Physiol. 2014 May;306(9):H1364-1370. [PMC free article] [PubMed]
Lee RH, Lyles KW, Pearson M, Barnard K, Colón-Emeric C. Osteoporosis screening and treatment among veterans with recent fracture after implementation of an electronic consult service. Calcif Tissue Int. 2014 Jun;94(6):659-664. [PMC free article] [PubMed]
Nelson AE, Elstad E, DeVellis RF, Schwartz TA, Golightly YM, Renner JB, Conaghan PG, Kraus VB, Jordan JM. Composite measures of multi-joint symptoms, but not of radiographic osteoarthritis, are associated with functional outcomes: the Johnston County Osteoarthritis Project. Disabil Rehabil. 2014;36(4):300-306. [PMC free article] [PubMed]
Orlowsky EW, Stabler TV, Montell E, Vergés J, Kraus VB. Monosodium urate crysta induced macrophage inflammation is attenuated by chondroitin sulphate: pre-clinical model for gout prophylaxis? BMC Musculoskelet Disord. 2014 Sep 27;15:318. [PMC free article] [PubMed]
Scholtens DM, Muehlbauer MJ, Daya NR, Stevens RD, Dyer AR, Lowe LP, Metzger BE, Newgard CB, Bain JR, Lowe WL Jr; HAPO Study Cooperative Research Group. Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy. Diabetes Care. 2014 Jan;37(1):158-166. [PMC free article] [PubMed]
Shalev I, Caspi A, Ambler A, Belsky DW, Chapple S, Cohen HJ, Israel S, Poulton R, Ramrakha S, Rivera CD, Sugden K, Williams B, Wolke D, Moffitt TE. Perinatal complications and aging indicators by midlife. Pediatrics. 2014 Nov;134(5):e1315-1323. [PMC free article] [PubMed]
Whitson HE, Arnold AM, Yee LM, Mukamal KJ, Kizer JR, Djousse L, Ix JH, Siscovick D, Tracy RP, Thielke SM, Hirsch C, Newman AB, Zieman S. Serum carboxymethyl-lysine, disability, and frailty in older persons: the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 2014 Jun;69(6):710-716. [PMC free article] [PubMed]
Whitson HE, Malhotra R, Chan A, Matchar DB, Østbye T. Comorbid visual and cognitive impairment: relationship with disability status and self-rated health among older Singaporeans. Asia Pac J Public Health. 2014 May;26(3):310-319. [PMC free article] [PubMed]
Winger JG, Mosher CE, Rand KL, Morey MC, Snyder DC, Demark-Wahnefried W. Diet and exercise intervention adherence and health-related outcomes among older long-term breast, prostate, and colorectal cancer survivors. Ann Behav Med. 2014 Oct;48(2):235-245. [PMC free article] [PubMed]
Wisniewski HG, Colón E, Liublinska V, Karia RJ, Stabler TV, Attur M, Abramson SB, Band PA, Kraus VB. TSG-6 activity as a novel biomarker of progression in knee osteoarthritis. Osteoarthritis Cartilage. 2014 Feb;22(2):235-241. [PMC free article] [PubMed]
Yin Z, Shi X, Kraus VB, Brasher MS, Chen H, Liu Y, Lv Y, Zeng Y. Gender-dependent association of body mass index and waist circumference with disability in the Chinese oldest old. Obesity (Silver Spring). 2014 Aug;22(8):1918-1925. [PMC free article] [PubMed]
Allen JD, Robbins JL, Vanbruggen MD, Credeur DP, Johannsen NM, Earnest CP, Pieper CF, Johnson JL, Church TS, Ravussin E, Kraus WE, Welsch MA. Unlocking the barriers to improved functional capacity in the elderly: rationale and design for the “Fit for Life trial”. Contemp Clin Trials. 2013 Sep;36(1):266-75. [PMC free article] [PubMed]
Bowling CB, Booth JN 3rd, Safford MM, Whitson HE, Ritchie CS, Wadley VG, Cushman M, Howard VJ, Allman RM, Muntner P. Nondisease-specific problems and all-cause mortality in the REasons for Geographic and Racial Differences in Stroke (REGARDS) study. J Am Geriatr Soc 2013 May;61(5):739-746. Minority Research Publication [PMC free article] [PubMed]
Chaudry SI, McAvay G, Chen, S, Whitson HE, Newman A, Krumholz HM, Gill T. Risk Factors for Hospital Admission Among Older Persons with Newly Diagnosed Heart Failure: Findings from the Cardiovascular Health Study. J Am Coll Cardiol 2013 Feb 12;61(6):635-642. [PMC free article] [PubMed]
Chou CH, Lee CH, Lu LS, Song IW, Chuang HP, Kuo SY, Wu JY, Chen YT, Kraus VB, Wu CC, Lee MT. Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees. Osteoarthritis Cartilage. 2013 Mar;21(3):450-61. [PMC free article] [PubMed]
Chou CH, Wu CC, Song IW, Chuang HP, Lu LS, Chang JH, Kuo SY, Lee CH, Wu JY, Chen YT, Kraus VB, Lee MT. Genome-wide expression profiles of subchondral bone in osteoarthritis. Arthritis Res Ther. 2013;15(6):R190. [PMC free article] [PubMed]
Cibere J, Sayre EC, Esdaile JM, Thorne A, Kopec JA, Singer J, Nicolaou S, Garnero P, Poole AR, Kraus VB, Saxne T, Wong H, Guermazi A. Associations of clinical and biomarker variables with cartilage damage in painful pre-radiographic knee osteoarthritis. Results from a population-based study. Osteoarthritis and Cartilage 2013;21(1):S161. [Abstract]
Dolfi DV, Mansfield KD, Kurupati RK, Kannan S, Doyle SA, Ertl HC, Schmader KE, Wherry EJ. Vaccine-induced boosting of influenza virus-specific CD4 T cells in younger and aged humans. PLoS One. 2013;8(10):e77164. [PMC free article] [PubMed]
Dmitrieva NO, Almeida DM, Dmitrieva J, Loken E, Pieper CF. A day-centered approach to modeling cortisol: diurnal cortisol profiles and their associations among US adults. Psychoneuroendocrinology. 2013 Oct;38(10):2354-65. [PMC free article] [PubMed]
Fillenbaum GG, Blay SL, Pieper CF, King KE, Andreoli SB, Gastal FL. The association of health and income in the elderly: experience from a southern state of Brazil. PLoS ONE, 2013, 8(9), e739130. [PMC free article] [PubMed]
Ghazi A, Landerman L, Lien L, Colón-Emeric C. Impact of Race on the Incidence of Hypoglycemia in Hospitalized Older Adults with Type 2 Diabetes Mellitus. Clinical Diabetes 2013;31(2):66. Minority Research Publication [Abstract]
Hunter DJ, Eckstein F, Kraus VB, Losina E, Sandell L, Guermazi A. Imaging biomarker validation and qualification report: sixth OARSI Workshop on Imaging in Osteoarthritis combined with third OA Biomarkers Workshop. Osteoarthritis Cartilage. 2013 Jul;21(7):939-42. [PMC free article] [PubMed]
Kraus VB, Worrell TW, Renner JB, Coleman RE, Pieper CF. High prevalence of contralateral ankle abnormalities in association with knee osteoarthritis and malalignment. Osteoarthritis Cartilage. 2013 Nov;21(11):1693-9. [PMC free article] [PubMed]
Kuchibhatla, M.N., Fillenbaum, G.G., Kraus, W.E., Cohen, H.J., & Blazer, D.G. Trajectory classes of body mass index in a representative elderly community sample. J Gerontol A Biol Sci Med Sci. 2013 Jun;68(6):699-704. Minority Research Publication [PMC free article] [PubMed]
Levin MJ, Schmader KE, Gnann JW, McNeil SA, Vesikari T, Betts RF, Keay S, Stek JE, Bundick ND, Su SC, Zhao Y, Li X, Chan IS, Annunziato PW, Parrino J. Varicella-zoster virus-specific antibody responses in 50-59-year-old recipients of zoster vaccine. J Infect Dis. 2013 Nov 1;208(9):1386-90. [PMC free article] [PubMed]
Nelson AE, Golightly YM, Renner JB, Schwartz TA, Kraus VB, Helmick CG, Jordan JM. Brief report: Differences in multijoint symptomatic osteoarthritis phenotypes by race and sex: the Johnston County Osteoarthritis Project. Arthritis Rheum. 2013 Feb;65(2):373-7. Minority Research Publication [PMC free article] [PubMed]
Nolan D, Kraus WE, Hauser E, Li YJ, Thompson DK, Johnson J, Chen HC, Nelson S, Haynes C, Gregory SG, Kraus VB, Shah SH. Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family. PLoS One. 2013;8(8):e71779. [PMC free article] [PubMed]
Povsic TJ, Sloane R, Zhou J, Pieper CF, Pearson MP, Peterson ED, Green JB, Cohen HJ, Morey MC. Lower levels of circulating progenitor cells are associated with low physical function and performance in elderly men with impaired glucose tolerance: a pilot substudy from the VA Enhanced Fitness trial. J Gerontol A Biol Sci Med Sci. 2013 Dec;68(12):1559-66. [PMC free article] [PubMed]
Povsic TJ, Sloane R, Green JB, Zhou J, Pieper CF, Pearson MP, Peterson ED, Cohen HJ, Morey MC. Depletion of circulating progenitor cells precedes overt diabetes: a substudy from the VA enhanced fitness trial. J Diabetes Complications. 2013 Nov-Dec;27(6):633-6. [PMC free article] [PubMed]
Ridaura VK, Faith JJ, Rey FE, Cheng J, Duncan AE, Kau AL, Griffin NW, Lombard V, Henrissat B, Bain JR, Muehlbauer MJ, Ilkayeva O, Semenkovich CF, Funai K, Hayashi DK, Lyle BJ, Martini MC, Ursell LK, Clemente JC, Van Treuren W, Walters WA, Knight R, Newgard CB, Heath AC, Gordon JI. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science. 2013 Sep 6;341(6150):1241214. [PMC free article] [PubMed]
Whitson HE, Whitaker D, Potter G, McConnell E, Tripp F, Sanders LL, Muir KW, Cohen HJ, Cousins SW. A low-vision rehabilitation program for patients with mild cognitive deficits. JAMA Ophthalmol. 2013 Jul;131(7):912-9. [PMC free article] [PubMed]
Wolfe F, Bolster MB, O’Connor CM, Michaud K, Lyles KW, Colón-Emeric CS. Bisphosphonate use is associated with reduced risk of myocardial infarction in patients with rheumatoid arthritis. J Bone Miner Res. 2013 May;28(5):984-91. [PMC free article] [PubMed]
Wu JM, Ward RM, Allen-Brady KL, Edwards TL, Norton PA, Hartmann KE, Hauser ER, Velez Edwards DR. Phenotyping clinical disorders: lessons learned from pelvic organ prolapse. Am J Obstet Gynecol. 2013 May;208(5):360-5. [PMC free article] [PubMed]
Zeng Y, Cheng L, Zhao L, Tan Q, Feng Q, Chen H, Shen K, Li J, Zhang F, Cao H, Gregory SG, Yang Z, Gu J, Tao W, Tian XL, Hauser ER. Interactions between social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China. BMC Geriatr. 2013 Sep 9;13:91. [PMC free article] [PubMed]
Blay SL, Fillenbaum GG, Andreoli SB, Gastal FL. Prevalence and Concomitants of Arthritis in the Elderly in Rio Grande Do Sul, Brazil. PLoS ONE 2012;7(9):e45418. Minority Research Publication [PMC free article] [PubMed]
Catterall JB, Hsueh MF, Stabler TV, McCudden CR, Bolognesi M, Zura R, Jordan JM, Renner JB, Feng S, Kraus VB. Protein Modification by Deamidation Indicates Variations in Joint Extracellular Matrix Turnover. J Biol Chem 2012 Feb 10;287(7):4640-4651. [PMC free article] [PubMed]
Chumbler NR, Quigley P, Li X, Morey M, Rose D, Sanford J, Griffiths P, Hoenig H. Effects of Telerehabilitation on Physical Function and Disability for Stroke Patients: A Randomized, Controlled Trial. Stroke 2012 Aug;43(8):2168-2174. [PubMed]
Cohen RR, Lagoo-Deenadayalan SA, Heflin MT, Sloane R, Eisen I, Thacker JM, Whitson HE. Exploring predictors of complication in older surgical patients: a deficit accumulation index and the Braden scale. J Am Geriat Soc 2012 Sep;60(9):1609-1615. [PMC free article] [PubMed]
Colon-Emeric C, Lee R, Barnard K, Pearson M, Lyles KW. Use of Regional Clinical Data to Identify Veterans for a Multi-Center Osteoporosis Electronic Consult Quality Improvement Intervention. Journal of Hospital Administration 2013 Nov;2(1):8-14. [PDF download link]
Genao L, Whitson HE, Zaas D, Sanders L, Schmader K. Functional Status after Lung Transplantation in Older Adults in the Post-Allocation Score Era. Am J Transplant 2013 Jan;13(1):157-166. [PMC free article] [PubMed]
Goode AP, Marshall SW, Renner JB, Carey TS, Kraus VB, Irwin DE, Sturmer T, Jordan JM. Lumbar Spine Radiographic Features and Demographic, Clinical, and Radiographic Knee, Hip and Hand Osteoarthritis. Arthritis Care Res (Hoboken) 2012 Oct;64(10):1536-1544. [PMC free article] [PubMed]
Hoenig H, Landerman LR, Shipp KM, Richardson M, Pieper C, Hubbard-Winkler S. A Preliminary Predictive Model for Wheelchair Use 4 Month after Receipt. Technology and Disability 2012;24(1):71-81. [Abstract]
Huebner JL, Landerman LR, Somers TJ, Kraus VB, Guilak F, Blumenthal JA, Caldwell DS, Rice JR, Keefe FJ. Inflammatory Biomarkers of Oa, Il-6 and Leptin Are Modifiable in Overweight/Obese Oa Patients with a Protocol That Combines Training in Pain Coping Skills and Weight Management. Osteoarthritis and Cartilage 2012;20(1):S38. [Abstract]
Huffman KM, Redman LM, Landerman LR, Pieper CF, Stevens RD, Muehbauer MJ, Wenner BR, Bain JR, Kraus VB, Newgard CB, Ravussin E, Kraus WE. Caloric Restriction Alters the Metabolic Response to a Mixed-Meal: Results from a Randomized, Controlled Trial. PLoS ONE 2012;7(4):e28190. [PMC free article] [PubMed]
Kuchibhatla MN, Fillenbaum GG, Hybels CF, Blazer DG. Trajectory classes of depressive symptoms in a community sample of older adults. Acta Psychiatr Scand 2012 Jun;125(6)492-501. Minority Research Publication [PMC free article] [PubMed]
Lee R, Colón-Emeric C. Effectiveness of osteoporosis therapy among frail, older adults: Should we carry out more trials? Aging Health 2012 (Oct);8(5):461-470. [Journal Issue link]
Miller PE, Morey MC, Hartman TJ, Snyder DC, Sloane R, Cohen HJ, Demark-Wahnefried W. Dietary Patterns Differ between Urban and Rural Older, Long-Term Survivors of Breast, Prostate, and Colorectal Cancer and Are Associated with Body Mass Index. J Acad Nutr Diet 2012;112(6):824-831. [PMC free article] [PubMed]
Morey MC, Pieper CF, Edelman DE, Yancy WS Jr, Green JB, Lum H, Peterson MJ, Sloane R, Cowper PA, Bosworth HB, Huffman KM, Cavanaugh JT, Hall KS, Pearson MP, Taylor GA. Enhanced Fitness: A Randomized Controlled Trial of the Effects of Home-Based Physical Activity Counseling on Glycemic Control in Older Adults with Prediabetes Mellitus. J Am Geriatr Soc 2012 Sep;60(9):1655-1662. [PMC free article] [PubMed]
Muoio DM, Noland RC, Kovalik JP, Seiler SE, Davies MN, Debalsi KL, Ilkayeva OR, Stevens RD, Kheterpal I, Zhang J, Covington JD, Baipeyi S, Ravussin E, Kraus W, Koves TR, Mynatt RL. Muscle-Specific Deletion of Carnitine Acetyltransferase Compromises Glucose Tolerance and Metabolic Flexibility. Cell Metab 2012 May;15(5):764-777. [PMC free article] [PubMed]
Nipp R, Sloane R, Rao AV, Schmader KE, Cohen HJ. Role of Pain Medications, Consultants, and Other Services in Improved Pain Control of Elderly Adults with Cancer in Geriatric Evaluation and Management Units. J Am Geriatr Soc 2012 Oct;60(10):1912-1917. [PMC free article] [PubMed]
Purser JL, Feng Q, Yi Z, Hoenig H. A New Classification of Function and Disability in China: Subtypes Based on Performance-Based and Self-Reported Measures. J Aging Health 2012 Aug;24(5):779-798. [PMC free article] [PubMed]
Purser JL, Golightly YM, Feng Q, Helmick CG, Renner JB, Jordan JM. Association of Slower Walking Speed with Incident Knee Osteoarthritis-Related Outcomes. Arthritis Care Res 2012 Jul;64(7):1028-1035. [PMC free article] [PubMed]
Sun AY, Nilsson KR, Jr. Early Repolarization: A Sword in the Haystack? Heart Rhythm 2012 Aug;9(8):1301-1302. [PubMed]
Thielke S, Whitson HE, Diehr P, O’Hare A, Kearney P, Chaudhry S, Zakai N, Kim D, Sekaran N, Sale J, Arnold A, Chaves P, Newman AB. Persistence and remission of musculoskeletal pain in community-dwelling older adults: results from the Cardiovascular Health Study. J Am Geriatr Soc 2012 Aug;60(8):1393-1400. [PMC free article] [PubMed]
Toles M, Barroso J, Colón-Emeric CS, Corazzini K, McConnell E, Anderson R. Staff Interaction Strageties that Optomize deliver of Transitional Care in a Skilled Nursing Facility: A Multiple-Case Study. Fam Community Health 2012 Oct-Dec;35(4):334-344. [PMC free article] [PubMed]
Whitson HE, Malhotra R, Chan A, Matchar DB, Ostbye T. Comorbid Visual and Cognitive Impairment: Relationship with Disability Status and Self-Rated Health among Older Singaporeans. Asia Pac J Public Health 2014 May;26(3):310-319. [PMC free article] [PubMed]
Whitson HE, Whitaker D, Sanders LL, Potter GG, Cousins SW, Ansah D, McConnell E, Pieper CF, Landerman L, Steffens DC, Cohen HJ. Memory deficit associated with worse functional trajectories in older adults in low vision rehabilitation for macular disease. J Am Geriatr Soc 2012 Nov;60(11):2087-2092. [PMC free article] [PubMed]
Wolfe F, Bolster M, O’Connor C, Michaud K, Lyles KW, Colón-Emeric CS. Bisphosphonate use is associated with reduced risk of myocardial infarction in patients with rheumatoid arthritis. J Bone Miner Res 2012 May;28(5):984-991. [PMC free article] [PubMed]
Yin ZX, Shi XM, Kraus VB, Fitzgerald SM, Qian HZ, Xu JW, Zhai Y, Sereny MD, Zeng Y. High Normal Plasma Triglycerides Are Associated with Preserved Cognitive Function in Chinese Oldest-Old. Age Ageing 2012 Sep;41(5):600-606. [PMC free article] [PubMed]
Blay SL, Fillenbaum GG, Marinho V, Andreoli SB, Gastal FL. Increased health burden associated with comorbid depression in older Brazilians with diabetes. J Affect Disord 2011 Nov;134(1-3):77-84. [PMC free article] [PubMed]
Brummett BH, Babyak MA, Grønbæk M, Barefoot JC. Positive emotion is associated with 6-year change in functional status in individuals aged 60 and older. The Journal of Positive Psychology 2011 Sept;6(3):216-223. [Abstract]
Cheng AWM, Stabler TV, Bolognesi M, Kraus VB. Selenomethionine inhibits IL-1β inducible nitric xxide synthase (iNOS) and cyclooxygenase 2 (Cox2) expression in primary human chondrocytes. Osteoarthritis Cartilage 2011 Jan;19(1):118-125. [PMC free article] [PubMed]
Christy SM, Mosher CE, Sloane R, Snyder DC, Lobach DF, Demark-Wahnefried W. Long-term dietary outcomes of the FRESH START intervention for breast and prostate cancer survivors. J Am Diet Assoc 2011 Dec;111(12):1844-1851. [PMC free article] [PubMed]
Denoble AE, Huffman KM, Stabler TV, Kelly SJ, Hershfield MS, McDaniel GE, Coleman RE, Kraus VR. Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation. Proc Natl Acad Sci U S A. Feb 1 2011;108(5):2088-2093. [PMC free article] [PubMed]
Feng Q, Purser JL, Zhen Z, Duncan PW. Less exercise and more TV: leisure-time physical activity trends of shanghai elders, 1998-2008. J Public Health (Oxf). 2011 Dec;33(4):543-550. [PubMed]
Golightly YM, Marshall SW, Kraus VB, Renner JB, Villaveces A, Casteel C, Jordan JM. Biomarkers of incident radiographic knee osteoarthritis: Do they vary by chronic knee symptoms? Arthritis Rheum 2011 Aug;63(8):2276-2283. [PMC free article] [PubMed]
Hall K, Pieper C, Edelman D, Yancy WS Jr, Green JB, Lum H, Peterson MJ, Sloane R, Cowper PA, Bosworth HB, Huffman KM, Cavanaugh JT, Chapman JG, Pearson MP, Howard TA, Ekelund CC, McCraw BL, Burrell JB, Taylor GA, Morey MC. Lessons learned when innovations go awry: A baseline description of a behavioral trial-the enhancing fitness in older overweight veterans with impaired fasting glucose study. Transl Behav Med 2011 Nov;1(4):573-587. [PMC free article] [PubMed]
Hayden KM, Jones RN, Zimmer C, Plassman BL, Browndyke JN, Pieper C, Warren LH, Welsh-Bohmer KA. Factor structure of the National Alzheimer’s Coordinating Centers uniform dataset neuropsychological battery: An evaluation of invariance between and within groups over time. Alzheimer Dis Assoc Disord 2011 Apr-Jun;25(2):128-137. [PMC free article] [PubMed]
Huffman KM, Pieper CF, Kraus VB, Kraus WE, Fillenbaum GG, Cohen HJ. relations of a marker of endothelial activation (s-VCAM) to function and mortality in community-dwelling older adults. J Gerontol A Biol Sci Med Sci 2011 Dec;66(12):1369-1375. [PMC free article] [PubMed]
Huffman KM, Slentz CA, Bateman LA, Thompson D, Muehlbauer MJ, Bain JR, Stevens RD, Wenner BR, Kraus VB, Newgard CB, Kraus WE. Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity. Diabetes Care 2011 Jan;34(1):174-176. [PMC free article] [PubMed]
Hybels CF, Blazer DG, Landerman LR, Steffens DC. Heterogeneity in symptom profiles among older adults diagnosed with major depression. Int Psychogeriatr 2011 Aug;23(6):906-922. [PMC free article] [PubMed]
Jones LW, Eves ND, Spasojevic I, Wang F, Il’yasova D. Effects of aerobic training on oxidative status in postsurgical non-small cell lung cancer patients: A pilot study. Lung Cancer 2011 Apr;72(1):45-51. [PMC free article] [PubMed]
Kenjale AA, Ham KL, Stabler T, Robbins JL, Johnson JL, Vanbruggen M, Privette G, Yim E, Kraus WE, Allen JD. Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease. J Appl Physiol 2011 Jun;110(6):1582-1591. [PMC free article] [PubMed]
Kuchibhatla MN, Fillenbaum GG. Trajectory classes of depression in a randomized depression trial of heart failure patients: A reanalysis of the SADHART-CHF trial. Am J Geriatr Pharmacother 2011 Dec;9(6):483-494. [PMC free article] [PubMed]
Landerman LR, Mustillo SA, Land KC. Modeling repeated measures of dichotomous data: Testing whether the within-person trajectory of change varies across levels of between-person factors. Soc Sci Res 2011 Sep 1;40(5):1456-1464. [PMC free article] [PubMed]
Lum H, Sloane R, Huffman KM, Kraus VB, Thompson DK, Kraus WE, Bain JR, Stevens R, Pieper CF, Taylor GA, Newgard CB, Cohen HJ, Morey MC. Plasma Acylcarnitines Are Associated with Physical Performance in Elderly Men. J Gerontol A Biol Sci Med Sci 2011 May;66(5):548-553. [PMC free article] [PubMed]
Nelson, AE, Chaudhary, S, Kraus, VB, Fang, F, Chen, J-C, Schwartz, TA, Shi, XA, Renner, JB, Stabler, TV, Helmick, CG, Caldwell, K, Poole, AR, Jordan, JM. Whole blood lead levels are associated with biomarkers of joint tissue metabolism in African American and white men and women: The Johnston County Osteoarthritis Project. Environ Res. 2011 Nov;111(8): 1208-1214. Minority Research Publication [PMC free article] [PubMed]
Nelson, AE, Renner, JB, Schwartz, TA, Kraus, VB, Helmick, CG, Jordan, JM. Differences in multijoint radiographic osteoarthritis phenotypes among African Americans and Caucasians: The Johnston County Osteoarthritis project. Arthritis Rheum. 2011 Dec;63(12):3843-3852. Minority Research Publication [PMC free article] [PubMed]
Ostbye T, Malhotra R, Landerman LR. Body mass trajectories through adulthood: Results from the National Longitudinal Survey of Youth 1979 Cohort (1981-2006). Int J Epidemiol 2011 Feb;40(1):240-250. [PubMed]
Pieper C, Redman L, Racette S, Roberts S, Bhapkar M, Rochon J, Martin C, Kraus W, Das S, Williamson D, Ravussin E. Development of adherence metrics for caloric restriction interventions. Clin Trials. 2011 Apr;8(2):155-164. [PMC free article] [PubMed]
Redman LM, Huffman KM, Landerman LR, Pieper CF, Bain JR, Muehlbauer MJ, Stevens RD, Wenner BR, Kraus VB, Newgard CB, Kraus WE, Ravussin E. Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women. J Clin Endocrinol Metab. 2011 Feb;96(2):E312-321. [PMC free article] [PubMed]
Sun AY, Koontz JI, Shah SH, Piccini JP, Nilsson KR Jr, Craig D, Haynes C, Gregory SG, Hranitzky PM, Pitt GS. The S1103Y cardiac sodium channel variant is associated with implantable cardioverter-defibrillator events in blacks with heart failure and reduced ejection fraction. Circ Cardiovasc Genet 2011 Apr;4(2):163-168. [PMC free article] [PubMed]
Whitson HE, Hastings SN, Landerman LR, Fillenbaum GG, Cohen HJ, Johnson KS. Black-White disparity in disability: The role of medical conditions. J Am Geriatr Soc 2011 May;59(5):844-850. Minority Research Publication [PMC free article] [PubMed]
Whitson HE, Steinhauser K, Ammarell N, Whitaker D, Cousins SW, Ansah D, Sanders LL, Cohen HJ. Categorizing the effect of comorbidity: A qualitative study of individuals’ experiences in a low-vision rehabilitation program. J Am Geriatr Soc 2011 Oct;59(10):1802-1809. [PMC free article] [PubMed]
Whitson HE, Thielke S, Diehr P, O’Hare AM, Chaves PH, Zakai NA, Arnold A, Chaudhry S, Ives D, Newman AB. Patterns and predictors of recovery from exhaustion in older adults: The cardiovascular health study. J Am Geriatr Soc 2011 Feb;59(2):207-213. [PMC free article] [PubMed]
Brummett BH, Boyle SH, Kuhn CM, Siegler IC, Williams RB. Socioeconomic status moderates associations between CNS serotonin and expression of beta2-integrins CD11b and CD11c. J Psychiatr Res 2010 Apr;44(6):373-377. [PMC free article] [PubMed]
Cavanaugh JT, Kochi N, Stergiou N. Nonlinear Analysis of Ambulatory Activity Patterns in Community-Dwelling Older Adults. J Gerontol A Bio Sci Med Sci 2010 Feb;65(2):197-203. [PMC free article] [PubMed]
Chen HC, Kraus VB, Li YJ, Nelson S, Haynes C, Johnson J, Stabler T, Hauser E, Gregory G, Kraus WE, Shah S. Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large multigenerational extended family. Arthritis Rheum. 2010 Mar;62(3):781-790. Minority Research Publication [PMC free article] [PubMed]
Chen TD, Anderson DJ, Chopra T, Choi Y, Schmader KE, Kaye KS. Poor Functional Status is an Independent Predictor of Surgical Site Infections due to Methicillin-Resistant Staphylococcus aureus in Older Adults. J Am Geriatric Soc 2010 Mar;58(3):527-532. [PMC free article] [PubMed]
Fillenbaum GG, Blay SL, Andreoli SB. Prevalence and Correlates of Functional Status in an Older Community-Representative Sample in Brazil. J Aging Health 2010 Apr;22(3):362-383. [PMC free article] [PubMed]
Fillenbaum GG, Kuchibhatla MN, Whitson HE, Batch BC,Svetkey LP, Pieper CF, Kraus WE, Cohen HJ, Blazer DG. Accuracy of self-reported height and weight in a community-based sample of older African Americans and Whites. J Gerontol A Biol Sci Med Sci 2010 Oct;65(10):1123-1129. Minority Research Publication [PMC free article] [PubMed]
Hall KSM, Crowley GM, McConnell ES, Bosworth HB, Sloane RS, Ekelund CC, Morey MC. Change in goal ratings as a mediating variable between self-efficacy and physical activity in older men. Ann of Behav Med 2010 Jun;39(3):267-273. [PMC free article] [PubMed]
Huffman KM, Hall KS, Sloane R, Peterson MJ, Bosworth HB, Ekelund CC, Pearson MP, Howard T, Pieper CF, Morey MC. Is Diabetes Associated with poorer self-efficacy and motivation for physical activity in older adults with arthritis? Scand J Rheumatol 2010;39(5):380-386. [PMC free article] [PubMed]
Huffman KM, Sloane R, Peterson MJ, Bosworth HB, Ekelund CC, Pearson MP, Howard T, Pieper CF, Morey MC. The impact of self-reported arthritis and diabetes on response to a home-based physical activity counseling intervention. Scan J Rheumatol 2010 May;39(3):233-239. [PMC free article] [PubMed]
Hybels CF, Pieper CF, Blazer DG, Fillenbaum GG, Steffens DC. Trajectories of mobility and IADL function in older patients diagnosed with major depression. Int J Geriatri Psychiatry 2010 Jan;25(1):74-81. [PMC free article] [PubMed]
Lee RH, Lyles KW, Colón-Emeric C. A review of the effect of anticonvulsant medications on bone mineral density and fracture risk. Am J Geriatr Pharmacother 2010 Feb;8(1):34-46. [PMC free article] [PubMed]
Mandelblatt JS, Sheppard VB, Hurria A, Kimmick G, Isaacs C, Taylor K, Kornblith AB, Noone A, Luta G, Tallarico M, Barry WT, Hunegs L, Zon R, Naughton M, Winer E, Hudis C, Edge SB, Cohen HJ, Muss H. Breast cancer adjuvant chemotherapy decisions in older women: the role of patient preference and interactions with physicians. J Clin Oncol 2010 Jul 1;28(19);3146-3153. [PMC free article] [PubMed]
Pavon JM, Whitson HE, Okun MS. Parkinson’s disease in women: a call for improved clinical studies and for comparative effectiveness research. Maturitas 2010 Apr;65(4):352-358. [PMC free article] [PubMed]
Peterson MJ, Morey MC, Giuliani C, Pieper CF, Evenson KR, Mercer V, Visser M, Brach JS, Kritchevsky SB, Goodpastor BH, Rubin S, Satterfield S, Simonsick ES, Health ABC Study. Walking in old age and development of metabolic syndrome: The Health, Aging, and Body Composition Study. Meta Syndr Relat Disord 2010 Aug;8(4):317-322. [PMC free article] [PubMed]
Whitson HE, Ansah D, Whitaker D, Potter G, Cousins SW, MacDonald H, Pieper CF, Landerman L, Steffens D, Cohen HJ. Prevalence and patterns of comorbid cognitive impairment in low vision rehabilitation for macular disease. Arch Gerontol Geriatr 2010 Mar-Apr;50(2):209-212. [PMC free article] [PubMed]
Zeng Y, Gu D, Purser JL, Hoenig H, Christakis N. Associations of environmental factors with elderly health and mortality in China. Am J Public Health 2010 Feb;100(2):298-305. [PMC free article] [PubMed]
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Brummett BH, Morey CM, Boyle SH, Mark DB. Prospective study of associations among positive emotion and functional status in older patients with coronary artery disease. J Gerontol B Psychol Sci Soc Sci 2009 Jun;64(4):461-469. [PMC free article] [PubMed]
Catterall JB, Barr D, Bolognesi M, Zura R, Kraus VB. Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate. Arthritis Res Ther 2009;11(2):R55. [PMC free article] [PubMed]
Fillenbaum GG, Blay SL, Andreoli SB, Gastal FL. Correlates of and relationship among lifetime alcohol abuse and alcohol dependence in older community residents in Brazil. Int Psychiatry 2009 Apr 1;6(2):40-44. [PMC free article] [PubMed]
Hastings SN, Whitson HE, Purser J, Sloane RI, Johnson KS. Emergency department discharge diagnosis and adverse health outcomes in older adults. J Am Geriatr Soc 2009 Oct;57(10):1856-1861. [PMC free article] [PubMed]
Huffman, KM, SH Shah, RD Stevens, JR Bain, M Muehlbauer, CA Slentz, CJ Tanner, M Kuchibhatla, JA Houmard, CB Newgard, Kraus WE. Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women. Diabetes Care. 2009 Sept;32(9):1678-1683. [PMC free article] [PubMed]
Hybels CF, Pieper CF, Blazer DG. The complex relationship between depressive symptoms and functional limitations in community-dwelling older adults: the impact of sub-threshold depression. Psychol Med 2009 Oct;39(10):1677-1688. [PMC free article] [PubMed]
Kraus VB, McDaniel G, Worrell TW, Feng S, Vail TP, Varju G, Coleman RE. Association of bone scintigraphic abnormalities with knee malalignment and pain. Ann Rheum Dis 2009 Nov;68(11):1673-1679. [PMC free article] [PubMed]
Makowski L, Noland RC, Koves TR, Xing W, Ilkayeva OR, Muehlbauer MJ, Stevens RD, Muoio DM. Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation. FASEB J 2009 Feb;23(2):586-604. [PMC free article] [PubMed]
Mercer VS, Freburger JK, Chang SH, Purser JL. Step test scores are related to measures of activity and participation in the first 6 months after stroke. Phys Ther 2009 Oct;89(10):1061-1071. [PMC free article] [PubMed]
Morey MC, Snyder DC, V, Sloane R, Cohen HJ, Peterson B, Hartman TJ, Miller PE, Mitchell DC, Demark-Wahnefried W. Effects of home-based diet and exercise on functional outcomes among older, overweight long-term cancer survivors: RENEW: a randomized control trial. JAMA 2009 May 13;301(18):1883-1891. Selected as feature article for the JAMA Report video. [PMC free article] [PubMed]
Morey MC, Peterson MP, Pieper CF, Sloane R, Crowley GM, Cowper PA, McConnell ES, Bosworth HB, Ekelund CC, Pearson MP. The Veterans Learning to Improve Fitness and Function in Elders study: A randomized trial of primary care based physical activity counseling. J Am Geriatr Soc 2009 Jul;57(7):1166-1174. [PMC free article] [PubMed]
Mosher CE, Sloane R, Morey MC, Snyder DC, Cohen HJ, Miller PE, Demark-Wahnefried W. Associations between lifestyle factors and quality of life among older long-term breast, prostate, and colorectal cancer survivors. Cancer 2009 Sep 1;115(17):4001-4009. [PMC free article] [PubMed]
Noland R, Koves TR, Seiler S, Lum H, Lust RM, Ilkayeva O, Stevens R, Hegardt FG, Muoio DM. Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. J Biol Chem 2009 Aug 21;284(34):22840-22852. [PMC free article] [PubMed]
Sloane R, Snyder DC, Demark-Wahnefried W, Lobach D, Kraus WE. Comparing the 7-day physical activity recall with a triaxial accelerometer for measuring time in exercise. Med Sci Sports Exerc 2009 June;41(6):1334-1340. [PMC free article] [PubMed]
Stabler T, Byers S, Zura R, Kraus VB. Amino Acid Racemization Reveals Differential Protein Turnover in Osteoarthritic Articular and Meniscal Cartilage. Arthritis Res Ther. 2009;11(2):R34. [PMC free article] [PubMed]
Snyder DC, Morey MC, Sloane R, Stull V, Cohen HJ, Peterson B, Pieper CF, Hartman TJ, Miller PE, Mitchell DC, Demark-Wahnefried W. Reach out to ENhancE Wellness in older cancer survivors (RENEW): design, methods and recruitment challenges of a home-based exercise and diet intervention to improve physical function among long-term survivors of breast, prostate, and colorectal cancer. Psycho-Oncology 2009 Apr;18(4):429-439. [PMC free article] [PubMed]
Whitson HE, Sanders L, Pieper CF, Morey M, EZ Oddone, DT Gold, HJ Cohen. Correlation between symptoms and function in older adults with comorbidity. J Am Geriatr Soc 2009 Apr;57(4):676-682. [PMC free article] [PubMed]
Blay SL, Fillenbaum GG, Andreoli SB, Gastal FL. Equity of access to outpatient care and hospitalization among older community residents in Brazil. Medi Care 2008 Sept;46(9):930-937. [PubMed]
Brummett BH, Boyle SH, Siegler IC, Kuhn CM, Surwit RS, Garrett ME, Collins A, Ashley Koch A, Williams RB. HPA axis function in male caregivers: effect of the monoamine oxidase-a gene promoter (MAOA-uVNTR). Biol Psychol 2008 Oct;79(2):250-255. [PMC free article] [PubMed]
Carney RM, Slifer MA, Lin PI, Gaskell PC, Scott WK, Potocky CF, Hulette CM, Welsh-Bohmer KA, Schmechel DE, Vance JM, Pericak-Vance MA. Longitudinal follow-up of late-onset Alzheimer disease families. Am J Med Genet B Neuropsychiatr Genet 2008 Jul 5;147B(5):571-578. [PMC free article] [PubMed]
Chen HC, Shah S, Stabler TV, Li Y-J, Kraus VB. Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE Family study. Osteoarthritis Cartilage 2008 Sept;16(9):1054-1059. Minority Research Publication [PMC free article] [PubMed]
Chen H-C, Shah SH, Li YJ, Stabler TV, Jordan JM, Kraus VB. Inverse association of general joint hypermobility with hand and knee osteoarthritis and serum cartilage oligomeric matrix protein levels. Arthritis Rheum 2008 Dec;58(12):3854-3864. Minority Research Publication [PMC free article] [PubMed]
Demark-Wahnefried W and Aziz N. Health promotion and disease prevention among adult survivors. In SM Miller, DJ Bowen, RT Croyle and J Rowland (eds). Handbook of Behavioral Science and Cancer. Washington, DC: American Psychological Association, 2008; pp. 487-494.
Fillenbaum GG. Differential survival with Alzheimer disease. (Editorial) Neurology, 2008 Apr 1;70(14):1158-1160. Minority Research Publication [PubMed]
Fillenbaum GG, van Belle G, Morris JC, Mohs RC, Mirra SS, Davis PC, Tariot PN, Silverman JM, Clark CM, Welsh-Bohmer KA, Heyman A. Consortium to Establish a Registry for Alzheimer’s Disease (CERAD): the first twenty years. Alzheimers Dement 2008 Mar;4(2):96-109. Minority Research Publication [PMC free article] [PubMed]
Hastings SN, Purser JL, Johnson KS, Sloane RJ, Whitson HE. Frailty predicts some but not all adverse outcomes in older adults discharged from the emergency department. J Am Geriatri Soc 2008 Sep;56(9):1651-1657. [PMC free article] [PubMed]
Hastings SN, Whitson HE, White HK, Sloane R, MacDonald H, Lekan DA, McConnell ES. After-Hours Calls from Long-Term Care Facilities in a Geriatric Medicine Training Program. J Am Geriatr Soc 2007 Dec;55(12):1989-1994. [PubMed]
Huffman KM, Slentz CA, Johnson JL, Samsa GP, Duscha BD, Tanner CJ, Annex BH, Houmard JA, Kraus WE. Impact of Hormone Replacement Therapy on Exercise Training-Induced Improvements in Insulin Action in Sedentary Overweight Adults. Metabolism 2008 Jul;57(7):888-885. [PMC free article] [PubMed]
Huffman KM, Slentz CA, Bales CW, Houmard JA, Kraus WE. Relationships between Adipose Tissue and Cytokine Responses to a Randomized Controlled Exercise Training Intervention. Metabolism 2008 Apr;57(4):577-583. [PMC free article] [PubMed]
Huffman KM, Orenduff MC, Samsa GP, Houmard JA, Kraus WE, Bales CW. Dietary carbohydrate intake and high sensitivity C reactive protein in at-risk women and men. Am Heart J 2007 Nov;154(5):962-968. [PMC free article] [PubMed]
Morey MC, Peterson MJ, Pieper CF, Sloane R, Crowley GM, Cowper P, McConnell E, Bosworth H, Ekelund C, Pearson M, Howard T. Project LIFE—Learning to Improve Fitness and Function in Elders: methods, design, and baseline characteristics of randomized trial. J Rehabil Res Dev 2008;45(1):31-42. [PubMed]
Morey MC, Sloane R, Pieper CF, Peterson MJ, Pearson MP, Ekelund CC, Crowley GM, Demark-Wahnefried W, Snyder DC, Clipp EC, Cohen HJ. Effect of physical activity guidelines on physical function in older adults. J Am Geriatr Soc 2008 Oct;56(10):1873-1878. [PMC free article] [PubMed]
Peterson BL, Fillenbaum GG, Pieper CF, Heyman A. Home or nursing home: does place of residence affect longevity in patients with Alzheimer’s disease? Public Health Nurs 2008 Sept-Oct;25(5):490-497. [PubMed]
Purser JL, Kuchibhatla MN, Miranda ML, Blazer DG, Cohen HJ, Fillenbaum GG. Geographical segregation and IL-6: a biomarker of chronic inflammation in older adults. Biomark Med 2008;2(4):335-348. Minority Research Publication [PMC free article] [PubMed]
Singh M, Alexander K, Roger VL, Rihal CS, Whitson HE, Lerman A, Jahangir A, Nair KS. Frailty and its potential relevance to cardiovascular care. Mayo Clin Pro 2008 Oct;83(10):1146-1153. [PMC free article] [PubMed]
Whitson HE, Sanders L, Pieper CF, Gold DT, Papaioannou A, Richards JB, Adachi JD, Lyles KW, the CaMos Research Group. Depressive symptomatology and fracture risk in community-dwelling older men and women. Aging Clin Exp Res 2008 Dec;20(6):585-592. [PMC free article] [PubMed]
Whitson HE, Hastings SN, Lekan DA, Sloane R, White HK, McConnell ES. A quality improvement program to enhance after-hours telephone communication between nurses and physicians in a long-term care facility. J Am Geriatri Soc 2008;56(6):1080-1086. [PubMed]
Xiao X, Zhang ZX, Cohen HJ, Wang H, Li W, Wang T, Xu T, Liu A, Gai MY, Ying S, Schmitz O, Yi Z. Evidence of a relationship between infant birth weight and later diabetes and impaired glucose regulation in a Chinese population. Diabetes Care 2008 Mar;31(3):483-487. [PubMed]
Cavanaugh J, Coleman K, Gaines J, Morey M. Using step activity monitoring to characterize ambulatory activity in community-dwelling older adults. J Am Geriatr Soc 2007 Jan;55(1):120-124. [PubMed]
Fillenbaum, GG, Kuchibhatla M, Henderson VW, Clark CM, Taussig IM. Comparison of performance on the CERAD Neuropsychological Battery of Hispanic patients and cognitively normal controls at two sites. Clinical Gerontologist 2007;30(3):1-22. DOI:10.1300 Minority Research Publication [Abstract]
Ganesh S, Hayter A, Kim J, Sanford J, Sprigle S, Hoenig H. Wheelchair use by veterans newly prescribed a manual wheelchair. Arch Phys Med Rehabil 2007;88(4):434-439. [PubMed]
Hastings SN, Whitson HE, White H, Sloane R, MacDonald H, Lekan-Rutledge DA, McConnell ES. Development and Implementation of the TrAC (Tracking After-hours Calls) Database: A Tool to Collect Longitudinal Data on After-Hours Telephone Calls in Long-Term Care. J Am Med Assoc 2007 Mar;8(3):178-182. [PubMed]
Hoenig H, Pieper C, Branch LG, Cohen HJ. Effect of motorized scooters on physical performance and mobility: a randomized clinical trial. Arch Phys Med Rehabil 2007 Mar;88(3):279-286. [PubMed]
Huebner JL, DR Seifer and VB Kraus. A longitudinal analysis of serum cytokines in the Hartley guinea pig model of osteoarthritis. Osteoarthritis Cartilage 2007 Mar;15(3):354-356. [PMC free article] [PubMed]
Kraus VB, Stabler T, Luta G, Renner JB, Dragomir AD, Mordan JM. Interpretation of serum C-reactive protein (CRP) levels for cardiovascular disease risk is complicated by race, pulmonary disease, body mass index, gender, and osteoarthritis. Osteoarthritis Cartilage 2007 Aug;15(8):966-971. Minority Research Publication [PMC free article] [PubMed]
Monetti M, Levin MC, Watt MJ, Sajan MP, Marmor S, Hubbard BK, Stevens RD, Bain JR, Newgard CB, Farese Sr. RV, Hevener A, Farese Jr RV. Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. Cell Metab 2007 Jul;6(1):69-78. [PubMed]
Richards JB, Papaiouannou A, Adachi JD, Joseph L, Whitson HE, Prior JC, Goltzman D, Canadian Multicentre Osteoporosis Study Research Group. Effects of selective serotonin reuptake inhibitors on the risk of fracture. Arch Intern Med 2007 Jan 22;167(2):188-194. [PubMed]
Schiffman SS, Sattely-Miller EA, Taylor EL, Graham BG, Landerman LR, Zervakis J, Campagna LK, Cohen HJ, Blackwell S, Garst JL. Combination of flavor enhancement and chemosensory education improves nutritional status in older cancer patients. J Nutr Health Aging 2007 Sep-Oct;11(5):439-454. [PubMed]
Snyder DC, Sloane R, Haines PS, Miller P, Clipp E, Morey MC, Pieper C, Cohen H, Demark-Wahnefried W. The Diet Quality Index-Revised (DQI-R): A Tool to Promote and Evaluate Dietary Change among Older Cancer Survivors Enrolled in a Home-Based Intervention Trial. J Am Diet Assoc 2007 Dept;107(9):1519-1529. [PubMed]
Stull VB, Snyder DC, Demark-Wahnefried W. Lifestyle Interventions in Cancer Survivors: Designing Programs that Meet the Needs of this Vulnerable and Growing Population. J Nutr 2007 Jan;137(1 suppl):243S-248S. [PubMed]
Whitson HE, Cousins SW, Burchett BM, Hybels CF, Pieper CF, Cohen HJ. The combined effect of visual impairment and cognitive impairment on disability in older adults. J Am Geriatr Soc 2007 Jun;55(6):885-891. [PubMed]
Cohen A, Pieper C, Brown A, Bastian LA. Number of children and the risk of metabolic syndrome in women. J Womens Health (Larchmt) 2006 Jul-Aug;15(6):763-773. [PubMed]
Demark-Wahnefried W, Clipp EC, Morey MC, Pieper CF, Sloane R, Snyder DC, Cohen HJ. Lifestyle Intervention Development Study to Improve Physical Function in Older Adults with Cancer: Outcomes from Project LEAD. J Clin Oncol 2006 Jul 20;24:3465-3473. [PMC free article] [PubMed]
Demark-Wahnefried W, Aziz N. Health promotion and disease prevention among adult survivors. In SM Miller, DJ Bowen, RT Croyle and J Rowland (eds). Handbook of Behavioral Science and Cancer. Washington, DC: American Psychological Association.
Dominick K, Morey MC. Adherence to Physical Activity in Patient Treatment Adherence: Concepts, Interventions and Measurement. Lawrence Erlbaum Associates, Inc., Mahwah, NJ.
Fillenbaum GG, Hybels CF, Pieper CF, Konrad TR, Burchett BM, Blazer DG. Provider characteristics related to antidepressant use in the elderly. J Am Geriatr Soc 2006, 54:942-949. Minority Research Publication [PDF link] [PubMed]
Fillenbaum GG, Hanlon JT. Racial and ethnic disparities in medication use among older adults. (editorial) Am J Geriatr Pharmacother 2006 Jun;4(2):93-95. Minority Research Publication [PubMed]
Hahs DW, McCauley JL, Crunk AE, McFarland LL, Gaskell PC, Jiang L, Slifer SH, Vance JM, Scott WK, Welsh-Bohmer KA, Johnson SR, Jackson CE, Pericak-Vance MA, Haines JL. A genome-wide linkage analysis of dementia in the Amish. Am J Med Genet B Neuropsychiatr Genet 2006 Mar 5;141B(2):160-166. [PMC free article] [PubMed]
Haines JL, Schnetz-Boutaud N, Schmidt S, Scott WK, Agarwal A, Postel EA, Olson L, Kenealy SJ, Hauser M, Gilbert JR, Pericak-Vance MA. Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6. Invest Ophthalmol Vis Sci 2006 Jan;47(1):329-335. [PubMed]
Hedayati SS, Bosworth HB, Kuchibhatla M, Kimmel PL, Szczech LA. The predictive value of self-report scales compared with physician diagnosis of depression in hemodialysis patients. Kidney Int 2006 May;69(9):1662-1668. [PubMed]
Heflin MT, Pollak KI, Kuchibhatla M, Branch LG, Oddone EZ. The impact of health status on physicians’ intentions to offer cancer screening to older women. J Gerontol A Biol Sci Med Sci 2006 Aug;61(8):844-850. [PubMed]
Hoenig H, Ganesh S, Taylor DH, Pieper C, Guralnik J, Fried L. Lower extremity physical performance and use of compensatory strategies for mobility. J Am Geriatr Soc 2006 Feb;54(2):262-269. [PubMed]
Huffman KM, Samsa GP, Slentz CA, Duscha BD, Johnson JL, Bales CW, Tanner CJ, Houmard JA, Kraus WE. Response of High Sensitivity C-Reactive Protein to Exercise Training in an At-Risk Population. Am Heart J 2006 Oct;152(4):793-800. [PubMed]
Huffman KM, Bowers JR, Dailiana Z, Huebner JL, Urbaniak JR, Kraus VB. Synovial Fluid Metabolites in Osteonecrosis. Rheumatology (Oxford) 2006 Mar;46(3):523-528. [PubMed]
Jia H, Zheng YE, Cowper DC, Stansbury JP, Wu SS, Vogel WB, Duncan PW, Reker DM. Race/ethnicity: Who is counting what? J Rehabil Res Dev. 2006 Jul-Aug;43(4):475-84. Minority Research Publication [Full text] [PubMed]
McCauley JL, Hahs DW, Jiang L, Scott WK, Welsh-Bohmer KA, Jackson CE, Vance JM, Pericak-Vance MA, Haines JL. Combinatorial Mismatch Scan (CMS) for loci associated with dementia in the Amish. BMC Med Genet 2006 Mar 3;7:19. [PMC free article] [PubMed]
Morey MC, Ekelund CC, Pearson MP, Crowley GM, Peterson MJ, Sloane R, Pieper CF, McConnell E, Bosworth H. Project LIFE: A partnership to improve physical activity in elders with multiple chronic illnesses. Journal of Aging and Physical Activity 2006 Jul;14(3):324-343. [PubMed]
Purser JL, Fillenbaum GG, Wallace RB. Memory Complaint Is Not Necessary for Diagnosis of Mild Cognitive Impairment and Does Not Predict 10-year Trajectories of Functional Disability, Word Recall or Short Portable Mental Status Questionnaire Limitations. J Am Geriatr Soc 2006 Feb;54(2):335-338. [PubMed]
Purser JL, Kuchibhatla MN, Fillenbaum GG, Harding T, Peterson ED, Alexander KP. Identifying Frailty Among Hospitalized Older Adults with Significant Coronary Artery Disease. J Am Geriatr Soc 2006 Nov;54(11):1674-1681. [PubMed]
Rao AV, Demark-Wahnefried W. The older cancer survivor. Crit Rev Oncol Hematol 2006 Nov;60(2):131-143. [PubMed]
Schmidt S, Hauser MA, Scott WK, Postel EA, Agarwal A, Gallins P, Wong F, Chen YS, Spencer K, Schnetz-Boutaud N, Haines JL, Pericak-Vance MA. Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. Am J Hum Genet 2006 May;78(5):852-864. [PMC free article] [PubMed]
Xu PT, Li YJ, Qin XJ, Scherzer CR, Xu H, Schmechel DE, Hulette CM, Ervin J, Gullans SR, Haines J, Pericak-Vance MA, Gilbert JR. Differences in apolipoprotein E3/3 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. Neurobiol Dis 2006 Feb;21(2):256-275. [PubMed]
Ashley-Koch AE, Shao Y, Rimmler JB, Gaskell PC, Welsh-Bohmer KA, Jackson CE, Scott WK, Haines JL, Pericak-Vance MA. An autosomal genomic screen for dementia in an extended Amish family. Neurosci Lett. 2005 May 13;379(3):199-204. [PubMed]
Criscione LG, Elliott AL, Stabler TV, Jordan JM, Pieper CF, Kraus VB. Variation of Serum Hyaluronan with Activity in Individuals with Knee Osteoarthritis. Osteoarthritis Cartilage 2005;13(9):837-840. [PubMed]
Demark-Wahnefried W, Aziz N, Rowland J, Pinto BM. Riding the Crest of the Teachable Moment: Promoting Long-Term Health After the Diagnosis of Cancer. J Clin Oncol 2005 Aug 20;23(24:5814-5830. [PMC free article] [PubMed]
Elliot A, Kraus V, Luta G, Stabler T, Renner JB, Woodard J, Dragomir AD, Helmick CG, Hochberg MC, Jordan JM. Serum hyaluronan levels and radiographic knee and hip osteoarthritis in African Americans and Caucasians in the Johnston County Osteoarthritis Project. Arthritis Rheum 2005 Jan;52(1):105-111. Minority Research Publication [PubMed]
Fisher SA, Abecasis GR, Yashar BM, Zareparsi S, Swaroop A, Iyengar SK, Klein BE, Klein R, Lee KE, Majewski J, Schultz DW, Klein ML, Seddon JM, Santangelo SL, Weeks DE, Conley YP, Mah TS, Schmidt S, Haines JL, Pericak-Vance MA, Gorin MB, Schulz HL, Pardi F, Lewis CM, Weber BH. Meta-analysis of genome scans of age-related macular degeneration. Hum Mol Genet 2005 Aug 1;14(15):2257-2264. [PubMed]
Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, Spencer KL, Kwan SY, Noureddine N, Gilbert JR, Schnetz-Boutaud N, Agarwal A, Postel EA, Pericak-Vance MA. Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration. Science 2005 Apr 15;308(5720):419-421. [PubMed]
Hoenig H, Landerman HR, Shipp KM, Pieper C, Pieper C, Richardson M, Pahel N, George L. A Clinical Trial of a Rehabilitation Expert Clinician Versus Usual Care for Providing Manual Wheelchairs. J Am Geriatr Soc 2005 Oct;53(10):1712-1720. [PubMed]
Ingram S, Seo P, Sloane R, Francis T, Clipp E, Doyle M, Montana G, Cohen H The association between oral health and general health and quality of life in older male cancer patients. J Am Geriatr Soc 2005 Sep;53(9):1504-1509. [PubMed]
Kuchibhatla M, Fillenbaum GG. Modeling Association in Longitudinal Binary Outcomes: A Brief Review. Aging and Mental Health 2005 May;9(3):196-200. [PubMed]
Piscoya JL, Fermor B, Kraus VB, Stabler TV, Guilak F. The influence of mechanical compression on the induction of osteoarthritis-related biomarkers in articular cartilage explants. Osteo & Cartilage 2005 Dec;13(12):1092-1099. [PubMed]
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Roberto K, Gold D (2001) Chronic Pain in Later Life: A Selectively Annotated Bibliography. Greenwood Press, Westport, CT.
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Sarraj S, Farb R, Martell RE. Reconstitution of DNA synthetic capacity in senescent normal human fibroblasts by expressing cellulal factors E2F and Mdm2. Exp Cell Res 2001 Nov 1;270(2):268-276. [PubMed]
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Small GW, Ercoli LM, Silverman DH, Huang S, Komo S, Bookheimer SY, Lavretsky H, Miller K, Siddarth P, Rasgon NL, Mazziotta JC, Saxena S, Wu H, Mega MS, Cummings JL, Saunders A, Pericak-Vance MA, Roses AD, Barrios JR, Phelps ME. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer’s disease. Proc Natl Acad Sci U S A 2000 May 23;97(11):6037-6042. [PMC free article] [PubMed]
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The Center for Aging provides resources for researchers, students, patients and family members.
Shelytia CoCroft, PhD
Shelytia CoCroft received her Ph.D. in Medical Sociology at Wayne State University where she examined the impact of socioeconomic status on knowledge of and attitudes toward cognitive decline. She is now a first year Postdoctoral Scholar at the Center for the Study of Aging and Human Development at Duke University Medical Center. Her co-mentors are Kathleen A. Welsh-Bohmer, Ph.D. (Professor of Psychiatry & Behavioral Sciences at Duke and Director, Alzheimer’s Disease Research Center) and Tyson Brown, Ph.D. (Assistant Professor of Sociology at Duke and Co-Director of the Center for Biobehavioral Health Disparities). Dr. CoCroft’s current research is part of the REVEAL-Scan Study, a study designed to investigate the impact of disclosing amyloid brain imaging results to cognitively healthy individuals at risk of Alzheimer’s disease by their family history with this condition. Her current research focuses on factors that contribute to participation of older adults in preclinical Alzheimer’s disease trials.
Anna H. Casey, PhD
Anna H. Casey, Ph.D. completed her doctorate in Behavior, Cognition and Neuroscience at American University and is a first-year fellow at the Duke Center for Aging. Dr. Casey’s dissertation research investigated the effects of task effort on the observing response in tufted capuchins at the NICHD’s Laboratory of Comparative Ethology. Her co-mentors are William C. Wetsel, PhD (Associate Professor of Psychiatry & Behavioral Sciences at Duke and Director of the Mouse Behavioral and Neuroendocrine Analysis Core Facility); Anne D. Yoder, (Braxton Craven Professor of Evolutionary Biology and Director of the Duke Lemur Center); and Richard O’Brien, (Disque D. Deane University Professor and Chair of Neurology. Dr. Casey is currently examining age-related cognitive decline in gray mouse lemurs. Results from her cognitive-behavioral tests will be compared with genotyping and brain imaging to assess the viability of the mouse lemur model for late-onset Alzheimer’s Disease.
Amy Thierry, PhD, MPH
Amy Thierry, Ph.D., M.P.H. comes to the Duke Aging Center’s Postdoctoral Research Training Program from the Pennsylvania State University College of Health and Human Development where she earned a Ph.D. in Biobehavioral Health with a minor in Demography. For her dissertation research, Dr. Thierry used Health and Retirement Study (HRS) data to examine racial/ethnic and gender differences in the relationship between chronic stress and physical disability, while integrating telomere length as a predictor of disability development. Her current co-mentors are Dr. Scott Lynch, PhD (Professor of Sociology at Duke) and Linda K. George, PhD (Arts and Sciences Professor of Sociology at Duke and Associate Director, Duke Center for the Study of Aging and Human Development). Dr. Thierry’s research at Duke will use the HRS to examine neighborhood stressors experienced by midlife and older adults to better understand how environmental context contributes to physical disability disparities. Her research includes measures of inflammation and telomere length, a biomarker of cellular aging, to elucidate potential cellular processes linking stress and physical disability.
Candace S. Brown, PhD
Candace S. Brown, PhD is a second-year Postdoctoral Scholar with the Center for the Study of Aging and Human Development at Duke University Medical Center (DUMC). She received her doctorate in Health Related Science/Gerontology in 2016 from Virginia Commonwealth University. Her dissertation focused on understanding the participatory motivations of midlife to older Black women who compete in triathlons Under the co-mentorship of Miriam C. Morey, PhD (Professor of Medicine-Geriatrics at Duke and Associate Director of Research, Durham VA GRECC) and Deborah T. Gold, PhD (Professor of Medical Sociology in the Departments of Psychiatry & Behavioral Sciences, Sociology, and Psychology and Neurosciences at Duke). Dr. Brown is developing skills in mixed methodologies to be applied to the study of aging, and her mentor for qualitative research is Linda M. Burton, PhD (James B. Duke Professor of Sociology and Director, Center for Child and Family Policy at Duke). Brown is currently studying the psychosocial complexities of exercise motivation among older veterans who exercise in the program Gerofit at the Durham VA.
Grace A. Noppert, PhD, MPH
Grace A Noppert, Ph.D., MPH is in her second year as a Postdoctoral Scholar with the Duke Center for Aging. She comes from the University of Michigan where she received her Ph.D. in Epidemiologic Science. Her dissertation work investigated social patterning of tuberculosis in Michigan. Her primary co-mentors are Angela O’Rand, Ph.D., (Professor Emeritus of Sociology at Duke and Director of the Center for Population Health and Aging and of the Duke University Population Research Institute) and Harvey Cohen, M.D.( Walter Kempner Professor of Medicine-Geriatrics and Director, Center for the Study of Aging & Human Development). Dr. Noppert’s research focuses on advancing our understanding of persistent infections across the life course as a potential cause of health disparities in aging and is specifically interested in investigating the link between early-life social disadvantage and later-life immune dysfunction.
Marianne Chanti-Ketterl, MD, PhD, MSPH
Marianne Chanti-Ketterl, MD, PhD, MSPH is in her second year as a Postdoctoral Scholar from the Duke Center for Aging. Dr. Chanti-Ketterl earned an M.D. from Universidad Internacional de las Americas in Costa Rica and an MSPH in Epidemiology from the University of South Florida. She completed her PhD at the University of South Florida in Aging Studies and Gerontology. Her dissertation research focused on the impact of lipoproteins on physical and cognitive function in older adults. Her co-mentors are Professor Brenda Plassman, Ph.D (Professor in the Department of Psychiatry & Behavioral Sciences and Neurology at Duke) and Deborah T. Gold, PhD (Professor of Medical Sociology in the Departments of Psychiatry & Behavioral Sciences, Sociology, and Psychology and Neurosciences at Duke) Dr. Chanti-Ketterl’s research focuses on genetic and environmental risk factors for cardiovascular disease, cognitive decline, and dementia. In addition, she has a special scientific interest in addressing health disparities among Latinos. Her current project looks at the association between pesticides and cognitive function in farmers from the Agricultural Health Study of Memory and Aging.
Cheryl Roberts, PhD
Cheryl Roberts, PhD, earned a master’s in public administration from Harvard University and a Ph.D. in sociology from the University of North Carolina, Chapel-Hill. Her mentors were Professors Kathie Harris and Glen Elder, Jr. Looking at the intersections of race, gender, and class, Roberts’ dissertation used the National Longitudinal Study of Adolescent Health to investigate the relationships among family disadvantage, school context, and educational attainment among African American males. Roberts’ mentor in the Duke RTP will be Professor Angela O’Rand in the Sociology Department. Her postdoctoral research will explore how earlier life disadvantages affect later life health, mental health, and well-being, and processes associated with risk and resilience.
Dan Hatch, PhD
Dan Hatch, PhD, earned his PhD in Psychological Science at Utah State University under the mentor ship of his dissertation chair, Professor Maria Norton. In his dissertation, “The Influence of Widowhood and Sociodemographic Moderators on Dementia and Alzheimer’s Disease Risk”, Hatch used data from a longitudinal cohort to examine how psychosocial stressors experienced throughout the life span altered risk for Alzheimer’s disease. Hatch began his postdoctoral fellowship at the Duke Aging Center with his mentor, Dr. Guy Potter of the Department of Psychiatry and Behavioral Sciences; Dr. Carl Pieper of the Department of Biostatistics and Bioinformatics will also act as a secondary mentor. Hatch’s research will examine the relationship between job strain and depression in a longitudinal cohort of workers at risk for occupational stress and will assess how this link is moderated by age-related executive functioning.
LaBarron Hill, PhD
LaBarron Hill, Ph.D. earned his PhD in Clinical Psychology, with a specialization in Health from The Ohio State University (Chair: Julian F. Thayer, Ph.D.). His dissertation, “The Influence of State and Trait Perseverative Cognition on Autonomic & Hemodynamic Regulation,” focused on the impact of psychological factors on cardiac functioning. LaBarron’s postdoctoral mentor is Dr. Keith Whitfield, Vice Provost of Academic Affairs and Professor of Psychology and Neuroscience. His postdoctoral research will examine the independent and interactive influence of psychosocial factors and underlying hemodynamic mechanisms on cognitive health and aging in African Americans. Dr. Hill is currently a Postdoctoral Scholar at SSRI, Duke University.
Nichole Lighthall, PhD
Nichole Lighthall earned a B.A. (2003) in psychology from UC Berkeley and a Ph.D. (2012) in Gerontology from the University of Southern California (Chair: Mara Mather, Ph.D.). In her dissertation, “Mechanisms of stress effects on learning and decision making in younger and older adults,” Nichole used biophysiological markers and functional MRI to determine how acute stress alters risk taking and reinforcement learning in early and late adulthood. Nichole’s postdoctoral research with Dr. Roberto Cabeza and Dr. Scott Huettel at the Center for Cognitive Neuroscience, will focus on determining how age-related changes to memory function affect economic decision making using neuroimaging techniques. Nichole is also interested in how emotion and motivation impact decision making across the life course. Dr. Lighthall is currently Assistant Professor of Psychology, University of Central Florida.
Abby Schwartz, MGS, MSW, PhD
Abby Schwartz, Ph.D. earned a master’s in Gerontology from Miami University (2005) and an MSW (2010) and PhD (2013) in Social Work from Boston College (Chair: Kathleen Mcinnis-Dittrich, Ph.D.) . Her dissertation, “Moderators of the impact of sociodemographic and economic factors on the well-being of caregiving men: implications for social work practice and policy,” explored issues of caregiving and men. Her postdoctoral co-mentors are Dr. Cristina Hendrix from DUSON and Dr. Deborah Gold. Dr. Schwartz’s projects during her postdoc will include exploring the various predictors of caregiver psychological well-being and the conditions under which these predictor/well-being relationships may vary. Following the secondary data analysis, Abby will translate the quantitative findings into a qualitative exploration of the lived experience of cancer caregiving on the psychological well-being of the caregiver. This will include exploring why such significant relationships exist in the study model. Dr. Schwartz is currently Assistant Professor of Social Work, East Carolina University.
Dan Belsky, PhD
Dan received his Ph.D. in Health Policy & Management in 2012 from the Gillings School of Public Health at the University of North Carolina at Chapel Hill. His postdoctoral mentors are professors Avshalom Caspi and Terrie Moffitt. Dan’s research leverages cutting edge genome science and longitudinal data from population-based cohort studies to identify mechanisms in the etiology of chronic disease, with the aim of mobilizing policy and clinical practice to target these mechanisms for intervention. A key focus in his research is to identify modifiable features of the environment that mitigate or exacerbate genetic risks. Dr. Belsky is currently Assistant Professor, Division of Geriatrics, Duke University Medical Center.
Brandon Berry, PhD
Brandon received his PhD from the Sociology Department at UCLA in 2012 after completing a dissertation on the social psychology of losing everyday objects. His postdoctoral research project will examine the experience of age-related cognitive decline through a study of the informal social psychological process by which individuals discern ‘normal’ cognitive aging from pathological forms and then seek medical intervention. Dr. Berry’s primary mentor will be Professor Lynn Smith-Lovin in the Department of Sociology, while his secondary mentors will be Dr. Kathleen Welsh-Bohmer and Dr. Deborah T. Gold. Dr. Berry is currently a Postdoctoral Scholar at the Betty Irene Moore School of Nursing, University of California at Davis.
Natalia (Natasha) Dmitrieva, Ph.D.
Natasha Dmitrieva is an NIA-sponsored postdoctoral scholar, working under the mentorship of Dr. Carl Pieper at Center for the Study of Aging and Human Development, Duke University Medical Center. She holds a Ph.D. in Human Development and Family Studies from The Pennsylvania State University–University Park.
The substantive interest driving Natasha’s work is the examination of the stress-disease link among individuals in middle and older adulthood. In her dissertation, she examined individual differences in within-day and day-to-day variability in salivary cortisol. In her postdoctoral training, she is expanding this work by examining (1) dyadic co-trajectories in vascular health conditions and risk factors among older adult couples, (2) the effects of a mindfulness-based-weight-loss-maintenance intervention on self-reported and biological indicators of health, and (3) the effects of health behaviors related to management of Type 1 Diabetes on self-reported and biological indicators of disease activity. She is proficient in a number of statistical methods that are relevant to the developmental approach to the study of health in adulthood, including multilevel modeling, mixture modeling, and structural equation modeling. Dr. Dmitrieva is currently Assistant Professor of Psychology, Northern Arizona University.
Liza Genao, MD
Liza Genao received her medical degree in 2004 from UNPHU School of Medicine in the Dominican Republic. She completed training in Internal Medicine at Mayo Clinic in 2009 and Clinical Geriatrics at Duke University in 2011. Dr. Genao’s long term career is to improve the quality and equality of care of older adults with end-stage lung disease (ESLD). Her research seeks to understand the impact of aging and multi-morbidity on the functional status and quality of life of this population and derive specific multidisciplinary interventions targeted to those factors found to jeopardize these outcomes. The available medical treatments for ESLD minimally impact symptoms or change the disease progression, and involve challenges and barriers to which older patients are particularly vulnerable. Lung Transplantation (LT) and pulmonary rehabilitation (PR) are the best-demonstrated interventions to improve quality of life. As a result of the introduction of a new lung allocation scoring system (LAS) in the U.S. in 2005, the annual number of LT recipients 65 and older quadrupled. Having trained at Duke University, a leading center of excellence in LT, Dr. Genao became interested on analyzing how the lives of these older Americans changed by the gift of a new lung. During her first post-doctoral training year, under the mentorship of Drs. Kenneth Schmader, Heather Whitson and David Zaas, she completed an analysis of the difference in functional trajectories after transplant between older and younger recipients. This retrospective cohort study used data from the United Network for Organ Sharing (UNOS) registry on all adults that received their first LT after the LAS. The key findings of this study, recently published in the American Journal of Transplantation, were that on average, the functional status at 1-year was higher than at transplantation for all recipients, age was not associated with different rates of decline over time, and even the older recipients rarely reached significant disability at 48-months post LT. Dr. Genao ongoing studies include: survival benefit for older adults with LT compared to remaining on wait-list, causes of death after LT and healthcare utilization before and after LT in older Medicare Beneficiaries. In January of 2012, Dr. Genao’s participated, in a multidisciplinary workshop held by the Association of Specialty Professors, National Institutes of Health (including NHLBI, NIA, NIAID, NIDDK) and the American Geriatrics Society (AGS), to address issues related to kidney, liver, heart and lung transplantation in older adults and propose the agenda for future research. Also during this year she became an awardee of the Hartford Scholar in the Center of Excellence in Geriatric Medicine and Training program at Duke University. She has served in the AGS Junior Faculty Research Special Interest Group Steering Committee and the Duke Institutional Review Board since 2011. Dr. Genao is currently Medical Instructor, Department of Medicine, Duke University Medical Center.
Lydia K. Manning, MGS, PhD
Lydia is a postdoctoral scholar at Duke University’s Center for Aging, and her is postdoctoral mentor is Dr. Linda K. George. Lydia holds a PhD in Social Gerontology from Miami University in Oxford, OH. Her current areas of research interests include exploring resilience as a developmental process and the effect of resilience and religion on self-rated health and subjective well-being in later life. Lydia has presented research at the Gerontological Society of America and the Association for Gerontology in Higher Education. Topics of these presentations include spirituality and aging, volunteering in third age, gender and religious differences in older women, and religion as a pathway to emotional resilience. Furthermore, she has published several peer-reviewed articles in journals on similar topics in The Gerontologist, Gerontology and Geriatrics Education, Journal of Religion, Spiritualty and Aging, Journal of Women and Aging, and Journal of Religion and Health. In addition Lydia is a member of the Gerontological Society of America, the American Sociological Society, and the Association for Anthropology and Gerontology. Dr. Manning is currently Associate Professor and Program Faculty Leader for Gerontology, Concordia University Chicago.
Adrienne T. Aiken Morgan, PhD
Adrienne is a Postdoctoral Fellow at the Center for the Study of Aging and Human Development and the Center on Biobehavioral Health Disparities. She received her PhD in clinical psychology, with a concentration in neuropsychology and graduate certificate in gerontology, at the University of Florida. Her dissertation was entitled “Effects of Improved Physical Fitness on Cognitive/Psychological Functioning in Community-Dwelling, Sedentary Middle-Aged and Older Adults.” Dr. Aiken Morgan’s primary fellowship mentor is Dr. Keith Whitfield, Vice Provost of Academic Affairs and Professor of Psychology and Neuroscience. The focus of her research during her fellowship will be to understand the influence of health and sociocultural factors on cognitive aging among African Americans. Dr. Aiken-Morgan is currently Lecturing Fellow, Social Science Research Institute, Duke University.
Kathryn Starr, PhD, RD
Kathryn earned her PhD in Nutrition from the Department of Foods and Nutrition at the University of Georgia, and is mentored by Dr. Connie W. Bales in the Nutrition Laboratory at the Center for Aging. Her postdoctoral research focusing on examining the influences of diet and exercise interventions in older adults for two randomized clinical trials. One examines metabolic responses to exercise alone (differing in amount and intensity) and exercise plus weight loss, and she will be focusing on age-related differences in metabolic responses in these pre-diabetic subjects, looking at changes in insulin sensitivity and metabolic syndrome scores, body composition, intervention adherence, reported energy intake, and nutrient intake. She also works on a weight loss intervention trial in “fat and frail” older adults that uses protein supplementation to help protect lean body mass; functional status and lean body mass are the primary outcomes in this trial. Kathryn is also a Registered Dietitian and received her Certificate in Gerontology at the University of Georgia’s Institute of Gerontology. Dr. Starr is currently an Advanced Geriatric Fellow at the Durham VA Medical Center
JOSHUA L. ANDERSEN, PhD in Cell Biology and Immunology, University of Utah, 2006
Project: In the Kornbluth lab I’m seeking to understand age-associated changes in the regulation of cell death, and the possible link between these changes and the pathogenesis of Alzheimers disease and cancer.
Recent Publications: Andersen et al., 2005; Andersen et al., 2006
In his own words: Prior to starting the research training program, my exposure to the field of aging research was limited to the relatively narrow scope of molecular biology. However, through weekly seminars I’ve been exposed to a wide range of topics concerning the field of aging and this has helped to broaden my focus as a scientist.
MATTHEW C. COSTELLO, PhD in Developmental Psychology, Duquesne University, Pittsburgh, PA, 2006
Project: My research examines age-related differences among younger and older adults in selective attention. The primary behavioral measures are a series of tasks in which subjects must detect and localize changes to visual displays. Additionally, I am involved with a series of neuroimaging studies examining age group differences in cognition and attention, with functional neuroimaging and diffusion tensor imaging as central measures.
Links: Duke Cognitive Psychology Lab
Recent Publications: Coming soon!
In his own words: The Research Training Program has helped my professional development immensely. My training has been intense and extensive, and the thoughtful support I have received has proven invaluable. I strongly recommend the program to anyone thinking of starting up postdoctoral research in aging.
NANCY A. DENNIS, Ph.D., The Catholic University of America, 2004
Project: My research focuses on the cognitive and neural mechanisms of memory and cognition in young and older adults. With respect to cognitive aging, my research concentrates on the examination of age related neural markers of cognitive decline, as well as mechanisms for neural compensation. My research combines behavioral, diffusion tensor imaging (DTI), and functional MRI (fMRI) approaches to explore the interaction of cognitive and neural processes in aging while focuses on the investigation of both episodic encoding and retrieval, as well as relational memory.
Links: Cabeza Lab, Cabeza Lab People
Recent Publications: See Cabeza Lab Publications, CV
In her own words: The RTP program has afforded me the opportunity to work directly with two of the top researchers in my field, Dr. Roberto Cabeza and Dr. Dave Madden. With their mentorship, I have completed 4 neuroimaging studies of my own and been fortunate enough to collaborate on over a half dozen more. These collaborations include working with researchers in the Department of Psychology and Neuroscience, Institute for Genome Science and Policy, and the Alzheimer’s Disease Research Center. My training has not only well prepared me for a career in my field, the Cognitive Neuroscience of Aging, but for work in the scientific research community in general.
JENNIFER R. DUNGAN, RN, PhD in Nursing Science with a Minor in Genetics from the University of Florida College of Nursing, 2006
Project (Project Mentor: William Kraus, MD): I have focused my training on two aspects of aging and genetics of cardiovascular disease: The first part of my project extends my dissertation work. It explores gene expression signatures of aging in cardiovascular disease using microarray. I am examining blood-based RNA from subjects in the Duke CATHGEN study of coronary heart disease to explore the effect of age on transcription profiles in people with a narrow burden of cardiovascular disease. This is an unbiased search for candidate genes that may help to explain some of the genetic contribution to aging in the context of heart disease. Second, I am focused on the genetic epidemiology of coronary artery disease and the phenomena of survivorship (survival in the context of having a chronic disease). Using a family-based database of early onset coronary artery disease (Duke GENECARD, PI: Elizabeth Hauser, PhD) and a population-based database of people who undergo cardiac catheterization (Duke CATHeterization GENetics/CATHGEN, PI: William Kraus, MD), I am exploring survival and survivorship in order to establish a proof of principle for the genetic contribution of this phenotype to heart disease. Through this project, I am also establishing a foundation in the study of temporal (time related) variables and their effect on gene association studies, so that we may better understand their impact on our analyses and appropriately control for their effects.
Links: Duke Center for Human Genetics, Duke CATHGEN Study, Duke GENECARD Study
In her own words: The Duke Aging RTP has provided me with a strong foundation in aging focused research, allowing me the flexibility to explore my own area of interest (survivorship in coronary heart disease) while also engaging me in the important age-related research taking place at Duke and beyond. It has given me the opportunity to expand my level of expertise and research skills and present my research at such meetings as the American Society of Human Genetics and the Council for the Advancement of Nursing Science, to name a few. Overall, Duke University is a unique atmosphere that offers tremendous resources for training, career development, and even peer socialization. The Duke Aging Center has a long-standing tradition of excellence and accomplishment, but without a precocious atmosphere. I feel this program has strengthened my foundation in aging research, made me a more well-rounded researcher, provided extraordinary networking opportunities, and prepared me for a smooth transition into independent academic research.
IRA J. SMITH
Project: Diabetes and its precursor, metabolic syndrome, are major risk factors for cardiovascular disease (CVD). Metabolic syndrome – the clustering of CVD risk factors – is a particularly powerful precursor to CVD. The prevalence of each of these conditions increases with age and are the cause of significant disease burden and disability in elderly populations. The development of countermeasures for metabolic syndrome in middle aged populations has the potential to have dramatic implications for the disability of elderly Americans by preventing, delaying or mollifying the development of disease in the elderly. Understanding the mechanisms whereby lifestyle interventions, such as exercise, mediate beneficial effects can lead to the design of better and more effective strategies to prevent disease and modify quality of life in the elderly. While physical activity has been observed to improve insulin sensitivity in individuals with the metabolic syndrome, the molecular mechanisms responsible for these benefits have yet to be elucidated. The goal of my project was to determine the effects of long-term endurance exercise training on the insulin-signaling cascade in middle-aged patients with the metabolic syndrome with the goal of understanding the development of disease in aging individuals.
Links: Faculty, Division of Cardiovascular Medicine
Recent Publications: Smith and Dodd, 2006
In his own words: The Research Training Program in Aging exposed me to different research disciplines and provided me with an appreciation for multidisciplinary research in aging. Topics covered during the weekly seminars were stimulating and informative, both on a professional level and a personal level.
Participation in the program also provided the opportunity for professional development. For instance, preparing the “mini-R01” grant proposal to gain acceptance into the program improved my writing skills and the experience of developing the proposal will be helpful when I write an actual R-01. In addition, Duke offers numerous opportunities for professional development through seminars (lasting from a couple of hours to 3 days), programs and other resources. Seminars cover topics such as: improving scientific writing, developing an R-01, and how to manage a lab.
SAMANTHA SOLIMEO, Ph.D. in Anthropology, University of Iowa, 2005; MPH in Gerontological Public Health, University of Iowa, 2002
Project – A Qualitative Study of the Older Male Experience of Osteoporosis (Postdoctoral Supervisor/ Mentor: Deborah T. Gold, PHD): This study will examine the self-reported experiences of community-dwelling men aged 50 and older with osteoporosis to improve our understanding of their social experience. In addition, the study will contribute to existing efforts to evaluate the reliability and validity of a recently developed measure of disease-related quality of life for male osteoporosis patients, the Male OPAQ. These aims will contribute to the larger goals of increasing knowledge about male osteoporosis patients, producing new information pertaining to male osteoporosis diagnosis and treatment, and developing a standardized instrument to measure disease-related quality of life among older men with osteoporosis.
In her own words: The Postdoctoral Fellowship has afforded me the opportunity to build upon my doctoral research by broadening my knowledge of how age and gender influence the experience of other chronic disorders in later life. It has provided me with the flexibility to translate my dissertation findings into published manuscripts. The fellowship has given me the institutional support to participate in professional organizations through committee work and scholarly presentations at the meetings of the Gerontological Society of America and the American Anthropological Association, as well as Editor of Anthropology & Aging Quarterly. The weekly seminars have introduced me to new areas of gerontological inquiry as well as to scholars from other disciplines who share similar research interests. Overall, the fellowship has been an important and productive experience, effectively bridging graduate school to an academic position.
WELCOME! The Chinese Longitudinal Healthy Longevity Survey (CLHLS) has been supported by NIA/NIH grants R01 AG023627-01 (PI: Zeng Yi) (Grant name: Demographic Analysis of Healthy Longevity in China) and P01 AG 008761 (PI: Zeng Yi; Program Project Director: James W. Vaupel), awarded to Duke University, with Chinese matching support for personnel costs and some local expenses. UNFPA and the China Social Sciences Foundation provided additional support for expanding the 2002 CLHLS survey. The Max Planck Institute for Demographic Research has provided support for international training since the CLHLS 1998 baseline survey. Finally, in December 2004 the China Natural Sciences Foundation and the Hong Kong Research Grants Council (RGC) partnered with NIA/NIH, providing grants to partially support the CLHLS project.
Until present, the CLHLS conducted face-to-face interviews with 8,959, 11,161, 20,428, 18,549 and 20,366, 10,188, and 7,192 individuals in 1998, 2000, 2002, 2005, 2008-09, 2011-12, and 2014, respectively, using internationally compatible questionnaires. Among the 96,843 interviews conducted in the seven waves, 16,547 were with centenarians, 22,232 with nonagenarians, 25,719 with octogenarians, 19,884 with younger elders aged 65-79, and 11,461 with middle-age adults aged 35-64. At each wave, survivors were re-interviewed, and deceased interviewees were replaced with new participants. Data on mortality and health status before dying for the 26,236 elders aged 65-110 who died between waves were collected in interviews with a close family member of the deceased.
The CLHLS has the largest sample of centenarians in the world according to a report in Science (see the report). Our general goal is to shed new light on a better understanding of the determinants of healthy longevity of human beings. We are compiling extensive data on a much larger population of the oldest-old aged 80-112 than has previously been studied, with a comparison group of younger elders aged 65-79. We propose to use innovative demographic and statistical methods to analyze longitudinal survey data. Our goal is to determine which factors, out of a large set of social, behavioral, biological, and environmental risk factors, play an important role in healthy longevity. The large population size, the focus on healthy longevity (rather than on a specific disease or disorder), the simultaneous consideration of various risk factors, and the use of analytical strategies based on demographic concepts make this an innovative demographic data collection and research project.
Our specific objectives are as follows:
- Collect intensive individual interview data including health, disability, demographic, family, socioeconomic, and behavioral risk factors for mortality and healthy longevity.
- Follow up the oldest-old and the comparison group of the younger elders, as well as some of the elders’ adult children to ascertain changes in their health status, care needs and costs, and associated factors. We will also ascertain mortality and causes of death, as well as care needs, costs, and health/disability status before death.
- Analyze the collected data to estimate the impacts of social, behavioral, environmental, and biological risk factors that are determinants of healthy longevity and mortality in the oldest-old.
- Compare the findings with results from other studies of large populations at advanced age.
The organizational framework of the CLHLS is summarized as follows:
|Sponsoring and Supporting Organizations||National Institute on Aging; United Nations Fund for Population Activities (UNFPA) and China National Foundation for Social Sciences joined NIA to co-sponsor the expanded survey in 2002; China National Natural Science Foundation and Hong Kong Research Grant Council joined NIA to co-sponsored the expanded survey since Dec. 2004; Peking University and Duke University have provided institutional supports: Max Planck Institute for Demographic Research has provided support for international training since the CLHLS 1998 baseline survey.|
|Principal Investigator & Steering Committee||Zeng Yi, Principal Investigator, Duke University and Peking University. The steering committee of the Chinese research team for this project consists of (alphabetically listed): Guo Zhigang, Li Ling, Liu Yuzhi, Edward Tu, Xiao Zhenyu, Zeng Yi, Zhang Chunyuan|
|International Longevity Projects Coordinator||James W. Vaupel, Coordinator of the Coordinated International Projects on Healthy Longevity in U.S., Europe, and China, Max Planck Institute for Demographic Research and Duke University|
|Data Collection Organizations||Peking University Center for Healthy Aging and Family Studies (CHAFS) and China Mainland Information Group (MIG)|
EXCELLENCE IN THE CARE OF AGING
The Center for the Study of Aging and Human Development was one of five centers for aging research established by the Surgeon General of the United States in 1955. It is the only continuously funded member of the original group. With more than 126 Faculty (Senior Fellows) and core staff members garnering and more than $20 million in annual age-related research funding, it remains a vital national resource for the study of aging. Current research includes studies of age-related functional decline and dysmobility, genomic, proteonic and metabolomic biomarkers of aging, exercise, osteoporosis, Alzheimer’s disease, cancer and aging, viral diseases of aging, depression in later life, caregiver stress, and religion/spirituality and health. The Center also is involved in an ambitious program designed to identify and educate future geriatricians.
Duke’s research and teaching programs in geriatrics are among the nation’s oldest. Geriatric Medicine at Duke has been a major strength of the Aging Center since 1984 with the creation of the Geriatric Division in the Department of Medicine and the Center. The Division of Geriatrics has distinguished itself as a leader in clinical care, research, and education. This sustained success is due in large part to its visionary leadership and abundant resources, including grants to the Aging Center such as the Claude D. Pepper OAIC and Hartford Center of Excellence. The VA Medical Center also hosts a Geriatrics Research, Education, and Clinical Center which is closely integrated with the Center. The Medicine/Dentistry Postgraduate Training Grant from the Department of Health and Human Services supports the fellowship program. These resources provide critical support and stability that allow the division to continue to provide excellent training for fellows and junior faculty. The Division has committed itself to placing its best trainees in leadership positions around the nation. We count numerous division chiefs and program directors among our former fellows and junior faculty.
Until recently, most Americans regarded aging as inevitable and undesirable. Growing older was seen as a process over which individuals had little control, much less as something that could be done well. Old age–the trip “over the hill”–was something to postpone for as long as possible.
But as the bulk of our nation’s population reaches their middle years, aging is being regarded with positive interest. Americans want to know how to live longer, healthier and more productive lives. They want to plan for retirement and keep their independence for as long as possible. In other words, they want to age well.
THE CENTER’S PAST
The Duke Center for the Study of Aging and Human Development has been studying successful aging–and applying the results of its research–for more than 50 years (see History of the Center). Long before “aging” became a topic of conversation and a national concern, far-sighted academicians at Duke University documented and understood the implications of an aging population. The leaders were men and women whose distinction is now recognized nationally and internationally, including biochemist Philip Handler, PhD, demographer Joseph Spengler, PhD, economist Juanita Kreps, PhD, psychiatrist Ewald W. Busse, MD, and Duke Chancellor William Anlyan, MD.
They were backed by an equally progressive university administration that chartered a university council on aging in 1955 to promote and coordinate multidisciplinary research, training and service. Two years later, the US Public Health Service designated the Duke center as one of five regional resource centers on aging. The Duke Center for the Study of Aging and Human Development is the oldest continually-funded member of the original group.
The center’s first initiatives included the Duke Longitudinal Studies, a 20-year project begun in 1956 that monitored the physical, mental, social and economic status of approximately 800 older adults. These studies, which received the 1983 Sandoz International Prize for multidisciplinary research in aging, documented the capacity of older adults to age well, helping revolutionize thinking about human aging. In 1975, the Older Americans Resources and Services (OARS) Program developed the first comprehensive technique for assessment of functional impairment in the elderly. OARS methods, updated to reflect changes in the aging population, still are used in hundreds of research studies and geriatric clinics across the country. Duke’s Geriatric Evaluation and Treatment (GET) Clinic, opened in 1967, continues to serve older adults from throughout the southeastern United States. Since 1988 the Center’s Long Term Care Resources Program has assisted North Carolina in developing and implementing sound public policies for serving older adults and their families in the long term.
LEADERSHIP IN AGING
Leadership in Aging has been one of the hallmarks of the Duke Center for the Study of Aging and Human Development. The center has produced six Presidents of The Gerontological Society of America: Ewald W. Busse, MD, Carl Eisdorfer, MD, George L. Maddox, PhD, Linda K. George, PhD, Harvey Jay Cohen, MD and Lisa Gwyther, MSW. Three center scholars have served as President of the American Geriatrics Society: Ewald W. Busse, MD, Dan G. Blazer, MD, PhD, and Harvey Jay Cohen, MD. At the international level, Dr. Busse served as President, and Dr. Maddox as Secretary General/Vice President of the International Association of Gerontology, 1985-89. These individuals and many others have held important offices in the most prestigious organizations in gerontology and geriatrics.
THE CENTER TODAY AND TOMORROW
Under the leadership of Director Harvey Jay Cohen, MD, the Duke center continues to serve as a national resource for information about aging and as a training ground for future generations of researchers, teachers, practitioners and planners
Duke researchers understand that the growing number of older adults will have a significant impact on our society’s arrangements for income maintenance, health care, social services, housing and transportation. Studies being conducted at Duke today already are addressing the complex health problems of a longer-lived population, and developing programs that will enable the elderly to receive care while maintaining their independence for as long as possible.
The center plans to initiate and expand its aging research in several areas in the future:
- Cellular and molecular biology of aging
- Interventions to enhance longevity
- Health care and health services utilization
- Cardiovascular disease and cancer
- Family relationships in later life
- Improving disability for osteoporosis and Pagets disease of bone
- Risk factors for chronic disease and mental illness
- The economic status of older adults
We invite interested researchers and colleagues at both Duke and other institutions to join in the collaboration.