Home » Claude D. Pepper Older Americans Independence Center (OAIC) » Cores » Research Education Component (REC)

Research Education Component (REC)

The Research Education Component (REC) recognizes that training in aging research faces several unique challenges, including difficulties recruiting geriatricians into research careers and a lack of training in the principles of aging research by other medical disciplines.

The objective of the Research Education Component will be to develop the next generation of researchers who will become leaders in integrating basic science and clinical insights into innovative interventions promoting reserve and resilience in late life.

AIMS of the Research Education Component
  1. Coordinate delivery of Aging research curriculum to early investigators across the University
  2. Provide a structure for individualized Aging and Research mentorship at Duke
  3. Evaluate the effectiveness of Aging research across the Duke OAIC

CORE LEADERS
Cathleen Colón-Emeric, MD, MHS
Associate Director-Clinical at the Durham VA Geriatrics Research Education and Clinical Center (GRECC), Adjunct Faculty at the Duke School of Nursing and Duke Clinical Research Institute

Current research focuses on the epidemiology, prediction, and prevention of osteoporotic fractures in elderly persons, and in improving the quality of care delivered to residents in skilled nursing facilities. Ongoing projects include a large, administrative database study of osteoporosis screening in men, a randomized trial of different staff education strategies to improve fall prevention in nursing homes, and several clinical demonstration projects. In 2017, Dr Colón-Emeric received the Clinical Sciences Research Mentoring Award from the Department of Medicine, and in 2018 she was appointed Associate Dean for Research Mentoring for the School of Medicine.

Kimberly Johnson, MD
Associate Professor of Medicine
Associate Director of the CTSA KL-2 program

Dr Johnson leads the Duke Center for REsearch to AdvanCe Healthcare Equity (REACH), where researchers study the effect of a clinician communication coaching intervention—teaching empathic skills and eliciting participatory behaviors—on the quality of communication in cardiology encounters with African American patients; test the use of a mobile app for African American patients receiving palliative care in the ICU and their families to self-report needs, obtain information about patient/family needs, and access decisional support; and develop and pilot test an implicit bias training intervention for providers.

2018 PEPPER CAREER DEVELOPMENT AWARDEES
Nazema Siddiqui, MD (Dept. of Obstetrics and Gynecology)
Effects of aging and the urinary microbiome on recurrent urinary tract infections

  1. Specific interests include: 1) pathophysiology of overactive bladder with particular emphasis on epigenetic mechanisms; and 2) studying the urinary microbiome with aging and in women with recurrent urinary tract infection. Additional interests include clinical outcomes research after surgery for prolapse and other pelvic floor disorders.

Corey Simon, DPT, PhD (Dept. of Orthopedic Surgery)
Physical Resilience to Pain with Activity Influences among Seniors (PRAISE) – Feasibility Study

  1. Research focuses on development of tailored multi-factorial interventions that prevent disability among older adults with low back pain. Low back pain poses a major risk to senior health, as it is the global leader in years lived with disability and strongly associated with mobility disability. However, it is not clear why some older adults with low back pain succumb to mobility disability while others do not. This REC study will determine the feasibility of assessing three factors that may explain mobility disability among older adults with low back pain: pain with activity, fear of movement, and dynamic inflammatory response to movement.

Tony Sung, MD (Dept. of Medicine, Division of Hematologic Malignancies and Cellular Therapy)
High intensity interval training to improve pre- and peri-transplant function and outcomes

  1. Research focuses on strategies to reduce complications of HCT and ranges from preclinical studies using murine models of HCT to Phase 1 and Phase 2 clinical trials. Areas of interest include the role of the microbiota (the trillions of bacteria living in and on our bodies), nutrition, and exercise in modulating HCT outcomes such as graft-versus-host disease (GVHD) and infections.

PREVIOUS PEPPER RESEARCH SCHOLARS

Since its inception, the Duke Pepper Center has produced an impressive portfolio of relevant research and innovations in faculty development. One of its many accomplishments is support and mentoring of numerous promising investigators whose careers focus on relevant aging related research at Duke. In 2009, in recognition of the contributions of these young investigators, career development and pilot project awardees, the Duke Pepper Center established a Duke Pepper Scholars Program.

Previous awardees:

Jason Allen, PhD, Cardiology

Kelli Allen, PhD, General Internal Medicine

Raquel R. Bartz, MD, Anesthesiology

Dan Belsky, PhD, Geriatrics

Beverly Brummett, MD, Medical Psychology

James T. Cavanaugh PT, PhD, Geriatrics

Jessica Chia, MD, Pulmonary, Allergy and Critical Care Medicine

Jennifer Dungan, RN, PhD, School of Nursing

William Michael Foster, PhD, Pulmonary and Critical Care Medicine

Farshid Guilak, PhD, Orthopedic Surgery and Cell Biology

Katherine Hall, PhD, Geriatrics

Rasheeda Hall, MD, Nephrology

Susan Nichole Hastings, MD, Geriatrics

Matthew Hirschey, PhD, Chemistry and Biochemistry

Kim Huffman, MD, Rheumatology and Immunology

Kimberly Johnson, MD, Geriatrics

Lee Jones, PhD, Radiation Oncology

Timothy Koves, PhD, Geriatrics

Richard Lee, MD, Endocrinology and Metabolism

Helen Lum, MD, Geriatrics

David Madden, PhD, Psychiatry and Behaviorial Sciences

Micah McClain, MD, Infectious Diseases

Mehri McKellar, MD, Infectious Diseases

Deborah M. Muoio, PhD, Endocrinology & Metabolomics

Kent Nilsson, MD, Cardiology

Amy Pastva, PhD, Community and Family Medicine

Juliessa Pavon, MD, Geriatrics

Matthew Peterson, PhD, Geriatrics

Thomas Povsic, MD, Cardiology

Jama L. Purser, PT, PhD, Geriatrics

Arati Rao, MD, Medicine

Gregory Sempowski, PhD, Duke Human Vaccine Institute

Svati H. Shah, MD, MHS, Epidemiology, Medical Genomics

Heather E. Whitson, MD, Geriatrics

RECENT PUBLICATIONS

Pavon JM, Sloane RJ, Pieper CF, Colón-Emeric CS, Cohen HJ, Gallagher D, Morey MC, McCarty M, Ortel TL, Hastings SN. Poor Adherence to Risk Stratification Guidelines Results in Overuse of Venous Thromboembolism Prophylaxis in Hospitalized Older Adults. J Hosp Med. 2018 Jun 1;13(6):403-404. [Institutional access] [PMC free article] [PubMed]

Hall RK, McAdams-DeMarco MA. Breaking the cycle of functional decline in older dialysis patients. Semin Dial. 2018 Apr 11. [Institutional access] [PMC free article-Available 09/01/2019] [PubMed]

Colón-Emeric CS, Corazzini K, McConnell E, Pan W, Toles M, Hall R, Batchelor-Murphy M, Yap TL, Anderson AL, Burd A, Anderson RA. Study of Individualization and Bias in Nursing Home Fall Prevention Practices. J Am Geriatr Soc. 2017 Apr;65(4):815-821. Minority Research Publication [Institutional access] [PMC free article] [PubMed]

Whitson, HE, Johnson, KS, Sloane, R, Cigolle, CT, Pieper, CF, Landerman, L, and Hastings, SN. “Identifying Patterns of Multimorbidity in Older Americans: Application of Latent Class Analysis.” Journal of the American Geriatrics Society (August 2016). [PMC free article] [PubMed]

Johnson, KS, Payne, R, Kuchibhatla, MN, and Tulsky, JA. “Are Hospice Admission Practices Associated With Hospice Enrollment for Older African Americans and Whites?” Journal of pain and symptom management (April 2016). [PMC free article] [PubMed]