Physical Measures Core (PMC)

The Physical Measures Core serves as the central resource for Center investigators seeking advice, training, laboratory access, and equipment for valid, sensitive, and reliable measures. The Physical Measures Core provides highly integrated, customized support to investigators supported by our Research Education Component, Pilot/Exploratory Studies Core, Externally Funded Projects, and the larger Duke Community engaged by the Duke Older Americans Independence Center.

AIMS of the Physical Measures Core
  1. Expertise and Consultation: To provide centralized expertise available for consultation on the measurement of reserve and resilience
  2. Development and Standardization: To develop measurement protocols and train personnel in administration and data collection
  3. Innovation and Standardization: To identify gaps in resiliency measures and develop or adapt innovative new measurement approaches across the adult lifespan for related outcomes

CORE LEADERS
Miriam Morey, PhD
Professor of Medicine in the Division of Geriatrics

The general focus of my work is exercise and aging. A number of studies examine how system-wide impairments serve as preclinical indicators of disability and overall decline in the quality of life of older adults. Ongoing studies examine the role of exercise training in attenuation or reversal of functional decline and examination of the effectiveness of different methods of physical activity counseling for home-based exercise.

Katherine S. Hall, PhD
Assistant Professor in the Division of Geriatrics, Duke Pepper Scholar, and Investigator in the Durham VA GRECC

My research is focused on developing evidence-based physical activity interventions for older adults with an eye to preserving functional independence and quality of life. I am particularly interested in developing exercise programs to promote physical and psychological well-being among older veterans with posttraumatic stress disorder (PTSD).


CURRENT SUPPORTED PROJECTS

Research Education Component
Daniel Belsky, PhDQuantification of molecular signatures of resilience in aging
Rasheeda Hall, MDResilience in older dialysis patients.”
Juliessa Pavon, MDMobile health technology to improve hospital ambulatory activity.”
Micah McClain, MDGenomic signatures of resilience to viral infections”

Pilot/Exploratory Studies Core
Miles Berger, MDPreoperative exercise to enhance resilience after surgery.”


FACULTY RESOURCES

Pepper researchers have an extraordinary opportunity for collaboration across Medical Center and University departments. These affiliated faculty members currently conduct interdisciplinary research with the Physical Measures Core.


Miriam Morey, PhD
Epidemiology/Exercise Science
Expertise and Access in assessment of:
Physical function: Performance-based and Self-report
Physical activity: Performance-based and Self-report
Services available
Portable telemetric oxygen uptake analyzer (Cosmed)
Activity tracking devices (SAM, Garmin)
Physical performance testing protocols & equipment


Katherine S. Hall, PhD
Exercise Psychology/Behavioral Medicine
Expertise and Access in assessment of:
Accelerometry
Psycho-social measures of behavior change
Physical activity: Performance-based and Self-report
Services available
Physical activity/sedentary monitoring (Actigraph)
Activity tracker analytic software (ActiLife)
Physical performance testing protocols & equipment
Psychosocial assessments/Health behavior theories


Amy M. Pastva, PT, MA, PhD
Physical Therapy/Exercise Physiology/Cell-Molecular Physiology/Biology
Expertise and Access in assessment of:
Translational science
Rodent models of disease, rodent exercise – young and aged mice
Cardiovascular and pulmonary fitness and function
Performance-based measures of physical status and function;
Rehabilitation and care transitions for medically complex patients
(acute, outpatient, home health)
Services available
Pulmonary function testing
Portable EKG
Physical status/Function (strength, mobility, cardiovascular, balance)/ Retraining equipment
Muscle physiology
Rodent: Treadmill exercise equipment


Avshalom Caspi, PhD
Psychologist/Neuroscientist
Expertise and Access in assessment of:
Psychiatric genetics
Mental health and personality
Longitudinal trajectories of mental health and predictors
Services available
Psychosocial measures of stress resilience
Genotyping
Personality assessment
Life-course epidemiology


Cathleen Colón-Emeric, MD, MHS
Geriatrician
Expertise and Access in assessment of:
Outcome measurement using administrative datasets and economic analyses
Measures of care delivery
Development of measures of reserve and resilience
Services available
Falls history/Falls risk assessments
Fall prevention strategies
Tele-technology


Deborah Gold, PhD
Sociologist
Expertise and Access in assessment of:
Psychosocial factors; Quality of life
Osteoporosis; Chronic illness; Pain
Services available
Measurement of quality of life, pain, psychological well-being, health behavior theories, self-efficacy


Gerda Fillenbaum, PhD
Gerontologist
Expertise and Access in assessment of:
Cognitive function; Neuropsychology measures
Health service use; Functional status
Services available
Measurement of functional status, comorbidity, quality of life, cognitive status, ADLs, depression


Heather E. Whitson, MD, MHS
Geriatrician
Expertise and Access in assessment of:
Cognition
Sensorial assessments
Services available
Measurement of sensorial impairments (cognitive, visual, pain, balance)
Comorbidity assessments


Helen Hoenig, MD
Physical Medicine and Rehabilitation
Expertise and Access in assessment of:
Performance-based measures of function using tele-technology
(gait, balance, motor coordination, ADLs)
GPS technology
Clinical measurement of physical, cognitive, I/ADLs
Services available
Functional retraining equipment
Tele-technology
Rehabilitation training equipment
Assistive technology/devices


Kevin Caves, BSME
Biomedical Engineer
Expertise and Access in assessment of:
Assistive technology; Technology and design for people with disabilities; Rehabilitation engineering
GPS/Spatial assessments
Design and fabrication of clinical and research tools
Integration of micro controllers and sensors
Software specification and development
Services available
Fabrication facilities (build and prototype custom devices)
3D printers
Assistive technology/devices
Remote monitoring of activities/physical performance
Fabrication of mechanical and electronic devices
Creation of software


S. Nicole Hastings, MD
Geriatrician
Expertise and Access in assessment of:
Cognition
Pharmacotherapy and comorbidity
Health service use
Services available
Assessment of healthcare utilization
Medication exposure/Prescribing practices


Terrie E. Moffitt, PhD
Psychologist/Neuroscientist
Expertise and Access in assessment of:
Mental health and bio-behavioral risk factors
Longitudinal trajectories of mental health and predictors
Gene-environment interplay and psychological health
Services available
Behavioral genetics
Mental health epidemiology
Psychological assessments


William E. Kraus, MD
Cardiologist
Expertise and Access in assessment of:
Cardiopulmonary exercise testing
Metabolic testing (RMR; OGTT, IVGTT)
Anthropometry assessments
Muscle molecular physiology
Integrative physiology
Services available
Body composition (Bod Pod, DXA)
Exercise physiology testing: CPET and strength testing; 6 MW
Metabolic testing (RMR; OGTT; IVGTT; infusion studies)
Physical activity tracking devices (RT3, Actigraph)
Mobile Health devices
Skeletal muscle biopsies
Phlebotomy
Clinical coordinator time for exercise, drug interaction studies
CV physical exam and EKG


RECENT PUBLICATIONS

Duan-Porter W, Cohen HJ, Demark-Wahnefried W, Sloane R, Pendergast JF, Snyder DC, Morey MC. Physical resilience of older cancer survivors: An emerging concept. Journal of geriatric oncology. 2016 Nov;7(6):471-478. [Institutional access] [PMC free article-Available 11/1/2017] [PubMed]

Hall KS, Cohen HJ, Pieper CF, Fillenbaum GG, Kraus WE, Huffman KM, Cornish MA, Shiloh A, Flynn C, Sloane R, Newby LK, Morey MC. Physical Performance Across the Adult Life Span: Correlates With Age and Physical Activity. The journals of gerontology. Series A, Biological sciences and medical sciences. 2017 Apr;72(4):572-578. [Institutional access] [PubMed]

Whitson HE, Duan-Porter W, Schmader KE, Morey MC, Cohen HJ, Colón-Emeric CS. “Physical Resilience in Older Adults: Systematic Review and Development of an Emerging Construct.” The journals of gerontology. Series A, Biological sciences and medical sciences. 2016 Apr;71(4):489-95. [PMC free article] [PubMed]