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OARS: THE METHOD AND ITS USES
The Duke OARS (Older Americans Resources and Services) Program, developed at the Duke Center for the Study of Aging and Human Development, was specifically designed as a means of determining the impact of services and alternative service programs on the functional status of older persons. The resulting brief, valid, and reliable instruments have been used for purposes as varied as individual clinical assessment of personal functional status, surveys of the status of adult populations, assessment of service utilization and service requirements, longitudinal investigations in community, clinic and long-term care settings, and training of service providers.
In order to examine the impact of services on functional state, OARS developed a three-part model:
1) Assessment of individual functional status, in order to group together people of comparable functional status;
2) Disaggregation of services into their generic components, and reaggregation according to actual use (service packages);
3) Use of a transition matrix to study the impact of specific service packages on specific functional states.
The OARS Multidimensional Functional Assessment Questionnaire (OMFAQ) operationalizes the first two parts of this model. The first section of the OMFAQ seeks information on five dimensions of functioning: Social Resources, Economic Resources, Mental Health, Physical Health, and ability to carry out Activities of Daily Living. On each dimension the information obtained is summarized on a 6-point scale where the values range from 1 (level of functioning excellent) to 6 (level of functioning totally impaired).
The second section of the OMFAQ inquires about the extent, intensity of utilization, and perceived need for each of 24 non-overlapping, broadly encompassing generic services.
Total administration time for the entire OMFAQ is about 45 minutes. Information is usually sought in a personal interview with the subject or an informant, although sections can be obtained by mail or telephone. No advanced or professional education is required to administer this questionnaire.
Training in the Use of the OARS Multidimensional Functional Assessment Questionnaire
Individual professionals and/or program directors who are planning to make use of the OARS multidimensional functional assessment technology on a regular programmatic basis or for a research project should review a video training tape (available from the Aging Center), to assure consistent and reliable data collection All who plan to conduct interviews on a regular basis should be trained in the administration of the OARS questionnaire. The OARS staff stands ready to assist OARS users in any way they can. Assistance includes suggestions for overcoming problems in administration, help in research design, and aid in data analysis and interpretation. A manual (please see below) is available.
Fillenbaum GG. Multidimensional Functional Assessment of Older Adults: The Duke Older Americans Resources and Services Procedures. Lawrence Erlbaum Associates, Hillsdale, NJ, 1988.
(Only electronic version, updated in 2005, now available)
Chap 1. The OARS Multidimensional Functional Assessment Questionnaire
Chap 2. The Validity and Reliability of the OARS Multidimensional Functional Assessment Questionnaire
Chap 3. Psychometric Structure and Computer-Based Rating of Part A. Functional Assessment
Chap 4. Services
Chap 5. Aggregating Functional Status and Services Information
Chap 6. The OARS Model: Use and Uses
Chap 7. Administration of the OARS Multidimensional Functional Assessment Questionnaire
Chap 8. Differences between the 1975 and 1988 Editions of the OARS Multidimensional Functional Assessment Questionnaire
Chap 9. Comparison Norms: Elderly Living in the Community, Institutions, and Attending Daycare
Appendix A. Variable List and Input Format for the 1988 Version of the OARS Multidimensional Functional Assessment Questionnaire
Appendix B. Coding Aids
Preliminary Questionnaire, Short Portable Mental Status Questionnaire (SPMSQ)
Question 34. Short Psychiatric Evaluation Schedule (SPES)
Question 42. Aid to Coding Common Prescribed Medications Taken in the Past Month
OARS MATERIALS AVAILABLE
Updated January, 2007
|OARS training video tape||$75.00|
|Manual (electronic, updated 2005)||$40.00|
|Questionnaire (electronic, specify WORD or
WordPerfect, and community or institutional version)
|Questionnaire (hard copy)||$ 5.00 + $2.00 postage and handling in US|
Center for the Study of Aging and Human Development
Duke University Medical Center
Durham, NC 27710, USA
JOURNAL ARTICLES, BOOKS, AND BOOK CHAPTERS PUBLISHED
Through June 2016
Bartlett DB, Connelly MA, AbouAssi H, Bateman LA, Tune KN, Huebner JL, Kraus VB, Winegar DA, Otvos JD, Kraus WE, Huffman KM. A novel inflammatory biomarker, GlycA, associates with disease activity in rheumatoid arthritis and cardio-metabolic risk in BMI-matched controls. Arthritis Res Ther. 2016 Apr 12;18:86. [PMC free article] [PubMed]
Catterall JB, Zura RD, Bolognesi MP, Kraus VB. Aspartic acid racemization reveals a high turnover state in knee compared with hip osteoarthritic cartilage. Osteoarthritis Cartilage. 2016 Feb;24(2):374-81. [PMC free article] [PubMed]
Chen S, Whitson H, Quiñones A, Thielke S. Comparative health and self-rated health are equivalently associated with health indicators among older adults. J Clin Epidemiol 2016 Feb;70:279-280. [PMC free article] [PubMed]
Cohen HJ, Walston JD, Rao SV, Schrier SL, Artz A. Partnership for Anemia: Clinical and Translational Trials in the Elderly Consortium. Renal Toxicity Associated with Salsalate in Elderly Adults with Anemia. J Am Geriatr Soc 2016 Apr;64(4):898-899. [PMC free article] [PubMed]
Dungan JR, Qin X, Horne BD, Carlquist JF, Singh A, Hurdle M, Grass E, Haynes C, Gregory SG, Shah SH, Hauser ER, Kraus WE. Case-Only Survival Analysis Reveals Unique Effects of Genotype, Sex, and Coronary Disease Severity on Survivorship. PLoS One. 2016 May 17;11(5):e0154856. [PMC free article] [PubMed]
Hybels CF, Pieper CF, Payne ME, Steffens DC. Late-life Depression Modifies the Association Between Cerebral White Matter Hyperintensities and Functional Decline Among Older Adults. Am J Geriatr Psychiatry 2016 Jan;24(1):42-49. [PMC free article] [PubMed]
Jamerson BD, Fillenbaum GG, Sloane R, Morey MC. A new method for identifying characteristics of needing help to take medications in an older representative community-resident population: the Older Adults Medication Assist Scale. J Am Geriatr Soc 2016 Jun; 64(6):1195–1202. Minority Research Publication [PMC free article] [PubMed]
Johnson KS, Payne R, Kuchibhatla MN. What are Hospice Providers in the Carolinas Doing to Reach African Americans in Their Service Area? J Palliat Med. 2016 Feb;19(2):183-189. Minority Research Publication [PMC free article] [PubMed]
LaFleur J, Rillamas-Sun E, Colón-Emeric CS, Knippenberg KA, Ensrud KE, Gray SL, Cauley JA, LaCroix AZ. Fracture Rates and Bone Density Among Postmenopausal Veteran and Non-Veteran Women From the Women’s Health Initiative. Gerontologist. 2016 Feb;56 Suppl 1:S78-90. [PMC free article] [PubMed]
Lee RH, Pearson M, Lyles KW, Jenkins PW, Colon-Emeric C. Geographic scope and accessibility of a centralized, electronic consult program for patients with recent fracture. Rural Remote Health 2016 Jan-Mar;16(1):3440. [PMC free article] [PubMed]
Lv YB, Yin ZX, Chei CL, Brasher MS, Zhang J, Kraus VB, Qian F, Shi XM, Matchar DB, Zeng Y. Serum Cholesterol Levels within the High Normal Range Are Associated with Better Cognitive Performance among Chinese Elderly. J Nutr Health Aging. 2016 Mar;20(3):280-7. [PMC free article] [PubMed]
McClain MT, Nicholson BP, Park LP, Liu TY, Hero AO 3rd, Tsalik EL, Zaas AK, Veldman T, Hudson LL, Lambkin-Williams R, Gilbert A, Burke T, Nichols M, Ginsburg GS, Woods CW. A Genomic Signature of Influenza Infection Shows Potential for Presymptomatic Detection, Guiding Early Therapy, and Monitoring Clinical Responses. Open Forum Infect Dis. 2016 Jan 19;3(1):ofw007. [PMC free article] [PubMed]
McGarrah RW, Craig DM, Haynes C, Dowdy ZE, Shah SH, Kraus WE. High-density lipoprotein subclass measurements improve mortality risk prediction, discrimination and reclassification in a cardiac catheterization cohort. Atherosclerosis. 2016 Mar;246:229-35. [PMC free article] [PubMed]
Peterson MJ, Thompson DK, Pieper CF, Morey MC, Kraus VB, Kraus WE, Sullivan P, Fillenbaum G, Cohen HJ. A Novel Analytic Technique to Measure Associations Between Circulating Biomarkers and Physical Performance Across the Adult Life Span. J Gerontol A Biol Sci Med Sci 2016 Feb;71(2):196-202. [PMC free article] [PubMed]
Potter GG, McQuoid DR, Whitson HE, Steffens DC. Physical frailty in late-life depression is associated with deficits in speed-dependent executive functions. Int J Geriatr Psychiatry 2016 May;31(5):466-474. [PMC free article] [PubMed]
Povsic TJ, Sloane R, Pieper CF, Pearson MP, Peterson ED, Cohen HJ, Morey MC. Endothelial Progenitor Cell Levels Predict Future Physical Function: An Exploratory Analysis From the VA Enhanced Fitness Study. J Gerontol A Biol Sci Med Sci. 2016 Mar;71(3):362-9. [PMC free article] [PubMed]
Stiber JA, Wu JH, Zhang L, Nepliouev I, Zhang ZS, Bryson VG, Brian L, Bentley RC, Gordon-Weeks PR, Rosenberg PB, Freedman NJ. The Actin-Binding Protein Drebrin Inhibits Neointimal Hyperplasia. Arterioscler Thromb Vasc Biol. 2016 May;36(5):984-93. [PMC free article] [PubMed]
Toles M, Colón-Emeric C, Naylor MD, Barroso J, Anderson RA. Transitional care in skilled nursing facilities: a multiple case study. BMC Health Serv Res. 2016 May 17;16:186. [PMC free article] [PubMed]
Whitson HE, Duan-Porter W, Schmader KE, Morey MC, Cohen HJ, Colón-Emeric CS. Physical Resilience in Older Adults: Systematic Review and Development of an Emerging Construct. J Gerontol A Biol Sci Med Sci 2016 Apr;71(4):489-495. [PMC free article] [PubMed]
Zeng Y, Nie C, Min J, Liu X, Li M, Chen H, Xu H, Wang M, Ni T, Li Y, Yan H, Zhang JP, Song C, Chi LQ, Wang HM, Dong J, Zheng GY, Lin L, Qian F, Qi Y, Liu X, Cao H, Wang Y, Zhang L, Li Z, Zhou Y, Wang Y, Lu J, Li J, Qi M, Bolund L, Yashin A, Land KC, Gregory S, Yang Z, Gottschalk W, Tao W, Wang J, Wang J, Xu X, Bae H, Nygaard M, Christiansen L, Christensen K, Franceschi C, Lutz MW, Gu J, Tan Q, Perls T, Sebastiani P, Deelen J, Slagboom E, Hauser E, Xu H, Tian XL, Yang H, Vaupel JW. Novel loci and pathways significantly associated with longevity. Sci Rep. 2016 Feb 25;6:21243. [PMC free article] [PubMed]
Zullig LL, Whitson HE, Hastings SN, Beadles C, Kravchenko J, Akushevich I, Maciejewski ML. A Systematic Review of Conceptual Frameworks of Medical Complexity and New Model Development. J Gen Intern Med 2016 Mar;31(3):329-337. [PMC free article] [PubMed]
Adams RN, Mosher CE, Blair CK, Snyder DC, Sloane R, Demark-Wahnefried W. Cancer survivors’ uptake and adherence in diet and exercise intervention trials: an integrative data analysis. Cancer. 2015 Jan 1;121(1):77-83. [PMC free article] [PubMed]
Band PA, Heeter J, Wisniewski HG, Liublinska V, Pattanayak CW, Karia RJ, Stabler T, Balazs EA, Kraus VB. Hyaluronan molecular weight distribution is associated with the risk of knee osteoarthritis progression. Osteoarthritis Cartilage 2015 Jan;23(1):70-76. [PMC free article] [PubMed]
Belsky DW, Caspi A, Houts R, Cohen HJ, Corcoran DL, Danese A, Harrington H, Israel S, Levine ME, Schaefer JD, Sugden K, Williams B, Yashin AI, Poulton R, Moffitt TE. Quantification of biological aging in young adults. Proc Natl Acad Sci U S A 2015 Jul 28;112(30):E4104-4110. [PMC free article] [PubMed]
Belsky DW, Caspi A, Israel S, Blumenthal JA, Poulton R, Moffitt TE. Cardiorespiratory fitness and cognitive function in midlife: neuroprotection or neuroselection? Ann Neurol 2015;77(4):607-617. [PMC free article] [PubMed]
Berger M, Nadler JW, Browndyke J, Terrando N, Ponnusamy V, Cohen HJ, Whitson HE, Mathew JP. Postoperative Cognitive Dysfunction: Minding the Gaps in Our Knowledge of a Common Postoperative Complication in the Elderly. Anesthesiol Clin 2015 Sep;33(3):517-550. [PMC free article] [PubMed]
Blay SL, Fillenbaum GG, Peluso ET. Differential characteristics of young and midlife adult users of psychotherapy, psychotropic medications, or both: information from a population representative sample in Sao Paulo, Brazil. A cross-sectional study. BMC Psychiatry 2015; 15:268. [PMC free article] [PubMed]
Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin AR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AM, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HP, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HM, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M. Designing a broad-spectrum integrative approach for cancer prevention and treatment. Semin Cancer Biol 2015 Dec;35 Suppl:S276-S304. [PMC free article] [PubMed]
Brenes-Salazar JA, Alshawabkeh L, Schmader KE, Hanlon JT, Forman DE. Clinical pharmacology relevant to older adults with cardiovascular disease. J Geriatr Cardiol 2015 May;12(3):192-195. [PMC free article] [PubMed]
Chou CH, Lee MT, Song IW, Lu LS, Shen HC, Lee CH, Wu JY, Chen YT, Kraus VB, Wu CC. Insights into osteoarthritis progression revealed by analyses of both knee tibiofemoral compartments. Osteoarthritis Cartilage 2015 Apr;23(4):571-580. [PubMed]
Fu Q, Cao J, Renner JB, Jordan JM, Caterson B, Duance V, Luo M, Kraus VB. Radiographic features of hand osteoarthritis in adult Kashin-Beck Disease (KBD): the Yongshou KBD study. Osteoarthritis Cartilage 2015 Jun;23(6):868-873. [PMC free article] [PubMed]
Genao L, Durheim MT, Mi X, Todd JL, Whitson HE, Curtis LH. Early and Long-term Outcomes of Older Adults after Acute Care Encounters for Chronic Obstructive Pulmonary Disease Exacerbation. Ann Am Thorac Soc 2015 Dec;12(12):1805-1812. [PMC free article] [PubMed]
Hall RK, Landerman LR, O’Hare AM, Anderson RA, Colón-Emeric CS. Chronic kidney disease and recurrent falls in nursing home residents: a retrospective cohort study. Geriatr Nurs. 2015 Mar-Apr;36(2):136-141. Minority Research Publication [PMC free article] [PubMed]
Hall RK, Toles M, Massing M, Jackson E, Peacock-Hinton S, O’Hare AM, Colón-Emeric C. Utilization of acute care among patients with ESRD discharged home from skilled nursing facilities. Clin J Am Soc Nephrol. 2015 Mar 6;10(3):428-434. Minority Research Publication [PMC free article] [PubMed]
Huang Z, Ma J, Chen J, Shen B, Pei F, Kraus VB. The effectiveness of low-level laser therapy for nonspecific chronic low back pain: a systematic review and meta-analysis. Arthritis Res Ther 2015 Dec 15;17:360. [PMC free article] [PubMed]
Huffman KM, Pieper CF, Hall KS, St Clair EW, Kraus WE. Self-efficacy for exercise, more than disease-related factors, is associated with objectively assessed exercise time and sedentary behaviour in rheumatoid arthritis. Scand J Rheumatol 2015;44(2):106-110. [PMC free article] [PubMed]
Hybels CF, Pieper CF, Payne ME, Steffens DC. Late-life depression modifies the association between cerebral white matter hyperintensities and functional decline among older adults. American Journal of Geriatric Psychiatry 2016;24:42-49. [PMC free article] [PubMed]
Kannan S, Kossenkov A, Kurupati RK, Xiang JZ, Doyle SA, Schmader KE, Schowe L, Ertl HC. A shortened interval between vaccinations with the trivalent inactivated influenza vaccine increases responsiveness in the aged. Aging (Albany NY) 2015 Dec;7(12):1077-1085. [PMC free article] [PubMed]
Kannan S, Kurupati RK, Doyle SA, Freeman GJ, Schmader KE, Ertl HC. BTLA expression declines on B cells of the aged and is associated with low responsiveness to the trivalent influenza vaccine. Oncotarget 2015 Aug 14;6(23):19445-19455. [PMC free article] [PubMed]
Kenzik KM, Morey MC, Cohen HJ, Sloane R, Demark-Wahnefried W. Symptoms, weight loss, and physical function in a lifestyle intervention study of older cancer survivors. J Geriatr Oncol 2015 Nov;6(6):424-432. [PMC free article] [PubMed]
Kraus VB, Blanco FJ, Englund M, Karsdal MA, Lohmander LS. Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use. Osteoarthritis Cartilage 2015 Aug;23(8):1233-1241. [PMC free article] [PubMed]
Kraus VB, Blanco FJ, Englund M, Henrotin Y, Lohmander LS, Losina E, Önnerfjord P, Persiani S. OARSI Clinical Trials Recommendations: Soluble biomarker assessments in clinical trials in osteoarthritis. Osteoarthritis Cartilage 2015 May;23(5):686-697. [PMC free article] [PubMed]
Lee RH, Pieper CF, Colón-Emeric C. Functional Impairments Mediate Association Between Clinical Fracture Risk and Type 2 Diabetes Mellitus in Older Women. J Am Geriatr Soc. 2015 Aug;63(8):1546-51. [PMC free article] [PubMed]
Lv YB, Yin ZX, Chei CL, Qian HZ, Kraus VB, Zhang J, Brasher MS, Shi XM, Matchar DB, Zeng Y. Low-density lipoprotein cholesterol was inversely associated with 3-year all-cause mortality among Chinese oldest old: data from the Chinese Longitudinal Healthy Longevity Survey. Atherosclerosis. 2015 Mar;239(1):137-142. [PMC free article] [PubMed]
Morey MC, Blair CK, Sloane R, Cohen HJ, Snyder DC, Demark-Wahnefried W. Group trajectory analysis helps to identify older cancer survivors who benefit from distance-based lifestyle interventions. Cancer 2015 Dec 15;121(24):4433-4440. [PMC free article] [PubMed]
Pearce MJ, Koenig HG, Robins CJ, Nelson B, Shaw SF, Cohen HJ, King MB. Religiously integrated cognitive behavioral therapy: a new method of treatment for major depression in patients with chronic medical illness. Psychotherapy (Chic) 2015 Mar;52(1):56-66. [PMC free article] [PubMed]
Povsic TJ, Sloane R, Pieper CF, Pearson MP, Peterson ED, Cohen HJ, Morey MC. Endothelial Progenitor Cell Levels Predict Future Physical Function: An Exploratory Analysis From the VA Enhanced Fitness Study. J Gerontol A Biol Sci Med Sci 2016 Mar;71(3):362-369. [PMC free article] [PubMed]
Souza AM, Fillenbaum GG, Blay SL. Prevalence and correlates of physical inactivity among older adults in Rio Grande do Sul, Brazil. PLoS One. 2015;10(2):e0117060. Minority Research Publication [PMC free article] [PubMed]
Whitson HE, Chou YH, Potter GG, Diaz MT, Chen NK, Lad EM, Johnson MA, Cousins SW, Zhuang J, Madden DJ. Phonemic fluency and brain connectivity in age-related macular degeneration: a pilot study. Brain Connect. 2015 Mar;5(2):126-135. [PMC free article] [PubMed]
Zeng Y, Chen H, Ni T, Ruan R, Feng L, Nie C, Cheng L, Li Y, Tao W, Gu J, Land KC, Yashin A, Tan Q, Yang Z, Bolund L, Yang H, Hauser E, Willcox DC, Willcox BJ, Tian XL, Vaupel JW. GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China. J Gerontol A Biol Sci Med Sci. 2015 Apr;70(4):426-433. [PMC free article] [PubMed]
Aslam I, Perjar I, Shi XA, Renner JB, Kraus VB, Golightly YM, Jordan JM, Nelson AE. Associations between biomarkers of joint metabolism, hand osteoarthritis, and hand pain and function: the Johnston County Osteoarthritis Project. J Rheumatol. 2014 May;41(5):938-944. Minority Research Publication [PMC free article] [PubMed]
Belsky DW, Shalev I, Sears MR, Hancox RJ, Lee Harrington H, Houts R, Moffitt TE, Sugden K, Williams B, Poulton R, Caspi A. Is chronic asthma associated with shorter leukocyte telomere length at midlife? Am J Respir Crit Care Med. 2014 Aug 15;190(4):384-391. [PMC free article] [PubMed]
Belsky DW, Suppli NP, Israel S. Gene-environment interaction research in psychiatric epidemiology: a framework and implications for study design. Soc Psychiatry Psychiatr Epidemiol. 2014 Oct;49(10):1525-1529. [PMC free article] [PubMed]
Blair CK, Morey MC, Desmond RA, Cohen HJ, Sloane R, Snyder DC, Demark-Wahnefried W. Light-intensity activity attenuates functional decline in older cancer survivors. Med Sci Sports Exerc. 2014 Jul;46(7):1375-1383. [PMC free article] [PubMed]
Blay SL, Fillenbaum GG, da Silva PF, Peluso ET. Use of psychotherapy in a representative adult community sample in São Paulo, Brazil. J Nerv Ment Dis. 2014 Sep;202(9):688-694. [PMC free article] [PubMed]
Blay SL, Fillenbaum GG, Pitta JC, Peluso ET. Factors associated with antidepressant, anxiolytic, and other psychotropic medication use to treat psychiatric symptoms in the city of São Paulo, Brazil. Int Clin Psychopharmacol. 2014 May;29(3):157-165. [PMC free article] [PubMed]
Clark N, Fan VS, Slatore CG, Locke E, Whitson HE, Nici L, Thielke SM. Dyspnea and pain frequently co-occur among Medicare managed care recipients. Ann Am Thorac Soc. 2014 Jul;11(6):890-897. [PMC free article] [PubMed]
Hastings SN, Sloane R, Morey MC, Pavon JM, Hoenig H. Assisted early mobility for hospitalized older veterans: preliminary data from the STRIDE program. J Am Geriatr Soc. 2014 Nov;62(11):2180-2184. [PMC free article] [PubMed]
Herati RS, Reuter MA, Dolfi DV, Mansfield KD, Aung H, Badwan OZ, Kurupati RK, Kannan S, Ertl H, Schmader KE, Betts MR, Canaday DH, Wherry EJ. Circulating CXCR5+PD-1+ response predicts influenza vaccine antibody responses in young adults but not elderly adults. J Immunol. 2014 Oct 1;193(7):3528-3537. [PMC free article] [PubMed]
Huffman KM, Koves TR, Hubal MJ, Abouassi H, Beri N, Bateman LA, Stevens RD, Ilkayeva OR, Hoffman EP, Muoio DM, Kraus WE. Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness. Diabetologia. 2014 Nov;57(11):2282-2295. [PMC free article] [PubMed]
Hunter DJ, Nevitt M, Losina E, Kraus V. Biomarkers for osteoarthritis: current position and steps towards further validation. Best Pract Res Clin Rheumatol. 2014 Feb;28(1):61-71. [PMC free article] [PubMed]
Hsueh MF, Önnerfjord P, Kraus VB. Biomarkers and proteomic analysis of osteoarthritis. Matrix Biol. 2014 Oct;39:56-66. [PubMed]
Hybels CF, George LK, Blazer DG, Pieper CF, Cohen HJ, Koenig HG. Inflammation and Coagulation as Mediators in the Relationships Between Religious Attendance and Functional Limitations in Older Adults. J Aging Health. 2014 Jun 26(4):679-697. [PMC free article] [PubMed]
Israel S, Caspi A, Belsky DW, Harrington H, Hogan S, Houts R, Ramrakha S, Sanders S, Poulton R, Moffitt TE. Credit scores, cardiovascular disease risk, and human capital. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17087-17092. [PMC free article] [PubMed]
Itty S, Day S, Lyles KW, Stinnett SS, Vajzovic LM, Mruthyunjaya P. Vitamin D deficiency in neovascular versus nonneovascular age-related macular degeneration. Retina. 2014 Sep;34(9):1779-1786. [PMC free article] [PubMed]
Kitzman DW, Nicklas B, Kraus WE, Lyles MF, Eggebeen J, Morgan TM, Haykowsky M. Skeletal muscle abnormalities and exercise intolerance in older patients with heart failure and preserved ejection fraction. Am J Physiol Heart Circ Physiol. 2014 May;306(9):H1364-1370. [PMC free article] [PubMed]
Lee RH, Lyles KW, Pearson M, Barnard K, Colón-Emeric C. Osteoporosis screening and treatment among veterans with recent fracture after implementation of an electronic consult service. Calcif Tissue Int. 2014 Jun;94(6):659-664. [PMC free article] [PubMed]
Nelson AE, Elstad E, DeVellis RF, Schwartz TA, Golightly YM, Renner JB, Conaghan PG, Kraus VB, Jordan JM. Composite measures of multi-joint symptoms, but not of radiographic osteoarthritis, are associated with functional outcomes: the Johnston County Osteoarthritis Project. Disabil Rehabil. 2014;36(4):300-306. [PMC free article] [PubMed]
Orlowsky EW, Stabler TV, Montell E, Vergés J, Kraus VB. Monosodium urate crysta induced macrophage inflammation is attenuated by chondroitin sulphate: pre-clinical model for gout prophylaxis? BMC Musculoskelet Disord. 2014 Sep 27;15:318. [PMC free article] [PubMed]
Scholtens DM, Muehlbauer MJ, Daya NR, Stevens RD, Dyer AR, Lowe LP, Metzger BE, Newgard CB, Bain JR, Lowe WL Jr; HAPO Study Cooperative Research Group. Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy. Diabetes Care. 2014 Jan;37(1):158-166. [PMC free article] [PubMed]
Shalev I, Caspi A, Ambler A, Belsky DW, Chapple S, Cohen HJ, Israel S, Poulton R, Ramrakha S, Rivera CD, Sugden K, Williams B, Wolke D, Moffitt TE. Perinatal complications and aging indicators by midlife. Pediatrics. 2014 Nov;134(5):e1315-1323. [PMC free article] [PubMed]
Whitson HE, Arnold AM, Yee LM, Mukamal KJ, Kizer JR, Djousse L, Ix JH, Siscovick D, Tracy RP, Thielke SM, Hirsch C, Newman AB, Zieman S. Serum carboxymethyl-lysine, disability, and frailty in older persons: the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 2014 Jun;69(6):710-716. [PMC free article] [PubMed]
Whitson HE, Malhotra R, Chan A, Matchar DB, Østbye T. Comorbid visual and cognitive impairment: relationship with disability status and self-rated health among older Singaporeans. Asia Pac J Public Health. 2014 May;26(3):310-319. [PMC free article] [PubMed]
Winger JG, Mosher CE, Rand KL, Morey MC, Snyder DC, Demark-Wahnefried W. Diet and exercise intervention adherence and health-related outcomes among older long-term breast, prostate, and colorectal cancer survivors. Ann Behav Med. 2014 Oct;48(2):235-245. [PMC free article] [PubMed]
Wisniewski HG, Colón E, Liublinska V, Karia RJ, Stabler TV, Attur M, Abramson SB, Band PA, Kraus VB. TSG-6 activity as a novel biomarker of progression in knee osteoarthritis. Osteoarthritis Cartilage. 2014 Feb;22(2):235-241. [PMC free article] [PubMed]
Yin Z, Shi X, Kraus VB, Brasher MS, Chen H, Liu Y, Lv Y, Zeng Y. Gender-dependent association of body mass index and waist circumference with disability in the Chinese oldest old. Obesity (Silver Spring). 2014 Aug;22(8):1918-1925. [PMC free article] [PubMed]
Allen JD, Robbins JL, Vanbruggen MD, Credeur DP, Johannsen NM, Earnest CP, Pieper CF, Johnson JL, Church TS, Ravussin E, Kraus WE, Welsch MA. Unlocking the barriers to improved functional capacity in the elderly: rationale and design for the “Fit for Life trial”. Contemp Clin Trials. 2013 Sep;36(1):266-75. [PMC free article] [PubMed]
Bowling CB, Booth JN 3rd, Safford MM, Whitson HE, Ritchie CS, Wadley VG, Cushman M, Howard VJ, Allman RM, Muntner P. Nondisease-specific problems and all-cause mortality in the REasons for Geographic and Racial Differences in Stroke (REGARDS) study. J Am Geriatr Soc 2013 May;61(5):739-746. Minority Research Publication [PMC free article] [PubMed]
Chaudry SI, McAvay G, Chen, S, Whitson HE, Newman A, Krumholz HM, Gill T. Risk Factors for Hospital Admission Among Older Persons with Newly Diagnosed Heart Failure: Findings from the Cardiovascular Health Study. J Am Coll Cardiol 2013 Feb 12;61(6):635-642. [PMC free article] [PubMed]
Chou CH, Lee CH, Lu LS, Song IW, Chuang HP, Kuo SY, Wu JY, Chen YT, Kraus VB, Wu CC, Lee MT. Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees. Osteoarthritis Cartilage. 2013 Mar;21(3):450-61. [PMC free article] [PubMed]
Chou CH, Wu CC, Song IW, Chuang HP, Lu LS, Chang JH, Kuo SY, Lee CH, Wu JY, Chen YT, Kraus VB, Lee MT. Genome-wide expression profiles of subchondral bone in osteoarthritis. Arthritis Res Ther. 2013;15(6):R190. [PMC free article] [PubMed]
Cibere J, Sayre EC, Esdaile JM, Thorne A, Kopec JA, Singer J, Nicolaou S, Garnero P, Poole AR, Kraus VB, Saxne T, Wong H, Guermazi A. Associations of clinical and biomarker variables with cartilage damage in painful pre-radiographic knee osteoarthritis. Results from a population-based study. Osteoarthritis and Cartilage 2013;21(1):S161. [Abstract]
Dolfi DV, Mansfield KD, Kurupati RK, Kannan S, Doyle SA, Ertl HC, Schmader KE, Wherry EJ. Vaccine-induced boosting of influenza virus-specific CD4 T cells in younger and aged humans. PLoS One. 2013;8(10):e77164. [PMC free article] [PubMed]
Dmitrieva NO, Almeida DM, Dmitrieva J, Loken E, Pieper CF. A day-centered approach to modeling cortisol: diurnal cortisol profiles and their associations among US adults. Psychoneuroendocrinology. 2013 Oct;38(10):2354-65. [PMC free article] [PubMed]
Fillenbaum GG, Blay SL, Pieper CF, King KE, Andreoli SB, Gastal FL. The association of health and income in the elderly: experience from a southern state of Brazil. PLoS ONE, 2013, 8(9), e739130. [PMC free article] [PubMed]
Ghazi A, Landerman L, Lien L, Colón-Emeric C. Impact of Race on the Incidence of Hypoglycemia in Hospitalized Older Adults with Type 2 Diabetes Mellitus. Clinical Diabetes 2013;31(2):66. Minority Research Publication [Abstract]
Hall KS, Howe CA, Rana SR, Martin CL, Morey MC. METs and accelerometry of walking in older adults: standard versus measured energy cost. Med Sci Sports Exerc. 2013 Mar;45(3):574-82. PMCID:5822436
Hunter DJ, Eckstein F, Kraus VB, Losina E, Sandell L, Guermazi A. Imaging biomarker validation and qualification report: sixth OARSI Workshop on Imaging in Osteoarthritis combined with third OA Biomarkers Workshop. Osteoarthritis Cartilage. 2013 Jul;21(7):939-42. [PMC free article] [PubMed]
Kraus VB, Worrell TW, Renner JB, Coleman RE, Pieper CF. High prevalence of contralateral ankle abnormalities in association with knee osteoarthritis and malalignment. Osteoarthritis Cartilage. 2013 Nov;21(11):1693-9. [PMC free article] [PubMed]
Kuchibhatla, M.N., Fillenbaum, G.G., Kraus, W.E., Cohen, H.J., & Blazer, D.G. Trajectory classes of body mass index in a representative elderly community sample. J Gerontol A Biol Sci Med Sci. 2013 Jun;68(6):699-704. Minority Research Publication [PMC free article] [PubMed]
Levin MJ, Schmader KE, Gnann JW, McNeil SA, Vesikari T, Betts RF, Keay S, Stek JE, Bundick ND, Su SC, Zhao Y, Li X, Chan IS, Annunziato PW, Parrino J. Varicella-zoster virus-specific antibody responses in 50-59-year-old recipients of zoster vaccine. J Infect Dis. 2013 Nov 1;208(9):1386-90. [PMC free article] [PubMed]
Nelson AE, Golightly YM, Renner JB, Schwartz TA, Kraus VB, Helmick CG, Jordan JM. Brief report: Differences in multijoint symptomatic osteoarthritis phenotypes by race and sex: the Johnston County Osteoarthritis Project. Arthritis Rheum. 2013 Feb;65(2):373-7. Minority Research Publication [PMC free article] [PubMed]
Nolan D, Kraus WE, Hauser E, Li YJ, Thompson DK, Johnson J, Chen HC, Nelson S, Haynes C, Gregory SG, Kraus VB, Shah SH. Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family. PLoS One. 2013;8(8):e71779. [PMC free article] [PubMed]
Povsic TJ, Sloane R, Zhou J, Pieper CF, Pearson MP, Peterson ED, Green JB, Cohen HJ, Morey MC. Lower levels of circulating progenitor cells are associated with low physical function and performance in elderly men with impaired glucose tolerance: a pilot substudy from the VA Enhanced Fitness trial. J Gerontol A Biol Sci Med Sci. 2013 Dec;68(12):1559-66. [PMC free article] [PubMed]
Povsic TJ, Sloane R, Green JB, Zhou J, Pieper CF, Pearson MP, Peterson ED, Cohen HJ, Morey MC. Depletion of circulating progenitor cells precedes overt diabetes: a substudy from the VA enhanced fitness trial. J Diabetes Complications. 2013 Nov-Dec;27(6):633-6. [PMC free article] [PubMed]
Ridaura VK, Faith JJ, Rey FE, Cheng J, Duncan AE, Kau AL, Griffin NW, Lombard V, Henrissat B, Bain JR, Muehlbauer MJ, Ilkayeva O, Semenkovich CF, Funai K, Hayashi DK, Lyle BJ, Martini MC, Ursell LK, Clemente JC, Van Treuren W, Walters WA, Knight R, Newgard CB, Heath AC, Gordon JI. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science. 2013 Sep 6;341(6150):1241214. [PMC free article] [PubMed]
Whitson HE, Whitaker D, Potter G, McConnell E, Tripp F, Sanders LL, Muir KW, Cohen HJ, Cousins SW. A low-vision rehabilitation program for patients with mild cognitive deficits. JAMA Ophthalmol. 2013 Jul;131(7):912-9. [PMC free article] [PubMed]
Wolfe F, Bolster MB, O’Connor CM, Michaud K, Lyles KW, Colón-Emeric CS. Bisphosphonate use is associated with reduced risk of myocardial infarction in patients with rheumatoid arthritis. J Bone Miner Res. 2013 May;28(5):984-91. [PMC free article] [PubMed]
Wu JM, Ward RM, Allen-Brady KL, Edwards TL, Norton PA, Hartmann KE, Hauser ER, Velez Edwards DR. Phenotyping clinical disorders: lessons learned from pelvic organ prolapse. Am J Obstet Gynecol. 2013 May;208(5):360-5. [PMC free article] [PubMed]
Zeng Y, Cheng L, Zhao L, Tan Q, Feng Q, Chen H, Shen K, Li J, Zhang F, Cao H, Gregory SG, Yang Z, Gu J, Tao W, Tian XL, Hauser ER. Interactions between social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China. BMC Geriatr. 2013 Sep 9;13:91. [PMC free article] [PubMed]
Blay SL, Fillenbaum GG, Andreoli SB, Gastal FL. Prevalence and Concomitants of Arthritis in the Elderly in Rio Grande Do Sul, Brazil. PLoS ONE 2012;7(9):e45418. Minority Research Publication [PMC free article] [PubMed]
Catterall JB, Hsueh MF, Stabler TV, McCudden CR, Bolognesi M, Zura R, Jordan JM, Renner JB, Feng S, Kraus VB. Protein Modification by Deamidation Indicates Variations in Joint Extracellular Matrix Turnover. J Biol Chem 2012 Feb 10;287(7):4640-4651. [PMC free article] [PubMed]
Chumbler NR, Quigley P, Li X, Morey M, Rose D, Sanford J, Griffiths P, Hoenig H. Effects of Telerehabilitation on Physical Function and Disability for Stroke Patients: A Randomized, Controlled Trial. Stroke 2012 Aug;43(8):2168-2174. [PubMed]
Cohen RR, Lagoo-Deenadayalan SA, Heflin MT, Sloane R, Eisen I, Thacker JM, Whitson HE. Exploring predictors of complication in older surgical patients: a deficit accumulation index and the Braden scale. J Am Geriat Soc 2012 Sep;60(9):1609-1615. [PMC free article] [PubMed]
Colon-Emeric C, Lee R, Barnard K, Pearson M, Lyles KW. Use of Regional Clinical Data to Identify Veterans for a Multi-Center Osteoporosis Electronic Consult Quality Improvement Intervention. Journal of Hospital Administration 2013 Nov;2(1):8-14. [PDF download link]
Genao L, Whitson HE, Zaas D, Sanders L, Schmader K. Functional Status after Lung Transplantation in Older Adults in the Post-Allocation Score Era. Am J Transplant 2013 Jan;13(1):157-166. [PMC free article] [PubMed]
Goode AP, Marshall SW, Renner JB, Carey TS, Kraus VB, Irwin DE, Sturmer T, Jordan JM. Lumbar Spine Radiographic Features and Demographic, Clinical, and Radiographic Knee, Hip and Hand Osteoarthritis. Arthritis Care Res (Hoboken) 2012 Oct;64(10):1536-1544. [PMC free article] [PubMed]
Hoenig H, Landerman LR, Shipp KM, Richardson M, Pieper C, Hubbard-Winkler S. A Preliminary Predictive Model for Wheelchair Use 4 Month after Receipt. Technology and Disability 2012;24(1):71-81. [Abstract]
Huebner JL, Landerman LR, Somers TJ, Kraus VB, Guilak F, Blumenthal JA, Caldwell DS, Rice JR, Keefe FJ. Inflammatory Biomarkers of Oa, Il-6 and Leptin Are Modifiable in Overweight/Obese Oa Patients with a Protocol That Combines Training in Pain Coping Skills and Weight Management. Osteoarthritis and Cartilage 2012;20(1):S38. [Abstract]
Huffman KM, Redman LM, Landerman LR, Pieper CF, Stevens RD, Muehbauer MJ, Wenner BR, Bain JR, Kraus VB, Newgard CB, Ravussin E, Kraus WE. Caloric Restriction Alters the Metabolic Response to a Mixed-Meal: Results from a Randomized, Controlled Trial. PLoS ONE 2012;7(4):e28190. [PMC free article] [PubMed]
Kuchibhatla MN, Fillenbaum GG, Hybels CF, Blazer DG. Trajectory classes of depressive symptoms in a community sample of older adults. Acta Psychiatr Scand 2012 Jun;125(6)492-501. Minority Research Publication [PMC free article] [PubMed]
Lee R, Colón-Emeric C. Effectiveness of osteoporosis therapy among frail, older adults: Should we carry out more trials? Aging Health 2012 (Oct);8(5):461-470. [Journal Issue link]
Miller PE, Morey MC, Hartman TJ, Snyder DC, Sloane R, Cohen HJ, Demark-Wahnefried W. Dietary Patterns Differ between Urban and Rural Older, Long-Term Survivors of Breast, Prostate, and Colorectal Cancer and Are Associated with Body Mass Index. J Acad Nutr Diet 2012;112(6):824-831. [PMC free article] [PubMed]
Morey MC, Pieper CF, Edelman DE, Yancy WS Jr, Green JB, Lum H, Peterson MJ, Sloane R, Cowper PA, Bosworth HB, Huffman KM, Cavanaugh JT, Hall KS, Pearson MP, Taylor GA. Enhanced Fitness: A Randomized Controlled Trial of the Effects of Home-Based Physical Activity Counseling on Glycemic Control in Older Adults with Prediabetes Mellitus. J Am Geriatr Soc 2012 Sep;60(9):1655-1662. [PMC free article] [PubMed]
Muoio DM, Noland RC, Kovalik JP, Seiler SE, Davies MN, Debalsi KL, Ilkayeva OR, Stevens RD, Kheterpal I, Zhang J, Covington JD, Baipeyi S, Ravussin E, Kraus W, Koves TR, Mynatt RL. Muscle-Specific Deletion of Carnitine Acetyltransferase Compromises Glucose Tolerance and Metabolic Flexibility. Cell Metab 2012 May;15(5):764-777. [PMC free article] [PubMed]
Nipp R, Sloane R, Rao AV, Schmader KE, Cohen HJ. Role of Pain Medications, Consultants, and Other Services in Improved Pain Control of Elderly Adults with Cancer in Geriatric Evaluation and Management Units. J Am Geriatr Soc 2012 Oct;60(10):1912-1917. [PMC free article] [PubMed]
Purser JL, Feng Q, Yi Z, Hoenig H. A New Classification of Function and Disability in China: Subtypes Based on Performance-Based and Self-Reported Measures. J Aging Health 2012 Aug;24(5):779-798. [PMC free article] [PubMed]
Purser JL, Golightly YM, Feng Q, Helmick CG, Renner JB, Jordan JM. Association of Slower Walking Speed with Incident Knee Osteoarthritis-Related Outcomes. Arthritis Care Res 2012 Jul;64(7):1028-1035. [PMC free article] [PubMed]
Sun AY, Nilsson KR, Jr. Early Repolarization: A Sword in the Haystack? Heart Rhythm 2012 Aug;9(8):1301-1302. [PubMed]
Thielke S, Whitson HE, Diehr P, O’Hare A, Kearney P, Chaudhry S, Zakai N, Kim D, Sekaran N, Sale J, Arnold A, Chaves P, Newman AB. Persistence and remission of musculoskeletal pain in community-dwelling older adults: results from the Cardiovascular Health Study. J Am Geriatr Soc 2012 Aug;60(8):1393-1400. [PMC free article] [PubMed]
Toles M, Barroso J, Colón-Emeric CS, Corazzini K, McConnell E, Anderson R. Staff Interaction Strageties that Optomize deliver of Transitional Care in a Skilled Nursing Facility: A Multiple-Case Study. Fam Community Health 2012 Oct-Dec;35(4):334-344. [PMC free article] [PubMed]
Whitson HE, Malhotra R, Chan A, Matchar DB, Ostbye T. Comorbid Visual and Cognitive Impairment: Relationship with Disability Status and Self-Rated Health among Older Singaporeans. Asia Pac J Public Health 2014 May;26(3):310-319. [PMC free article] [PubMed]
Whitson HE, Whitaker D, Sanders LL, Potter GG, Cousins SW, Ansah D, McConnell E, Pieper CF, Landerman L, Steffens DC, Cohen HJ. Memory deficit associated with worse functional trajectories in older adults in low vision rehabilitation for macular disease. J Am Geriatr Soc 2012 Nov;60(11):2087-2092. [PMC free article] [PubMed]
Wolfe F, Bolster M, O’Connor C, Michaud K, Lyles KW, Colón-Emeric CS. Bisphosphonate use is associated with reduced risk of myocardial infarction in patients with rheumatoid arthritis. J Bone Miner Res 2012 May;28(5):984-991. [PMC free article] [PubMed]
Yin ZX, Shi XM, Kraus VB, Fitzgerald SM, Qian HZ, Xu JW, Zhai Y, Sereny MD, Zeng Y. High Normal Plasma Triglycerides Are Associated with Preserved Cognitive Function in Chinese Oldest-Old. Age Ageing 2012 Sep;41(5):600-606. [PMC free article] [PubMed]
Blay SL, Fillenbaum GG, Marinho V, Andreoli SB, Gastal FL. Increased health burden associated with comorbid depression in older Brazilians with diabetes. J Affect Disord 2011 Nov;134(1-3):77-84. [PMC free article] [PubMed]
Brummett BH, Babyak MA, Grønbæk M, Barefoot JC. Positive emotion is associated with 6-year change in functional status in individuals aged 60 and older. The Journal of Positive Psychology 2011 Sept;6(3):216-223. [Abstract]
Cheng AWM, Stabler TV, Bolognesi M, Kraus VB. Selenomethionine inhibits IL-1β inducible nitric xxide synthase (iNOS) and cyclooxygenase 2 (Cox2) expression in primary human chondrocytes. Osteoarthritis Cartilage 2011 Jan;19(1):118-125. [PMC free article] [PubMed]
Christy SM, Mosher CE, Sloane R, Snyder DC, Lobach DF, Demark-Wahnefried W. Long-term dietary outcomes of the FRESH START intervention for breast and prostate cancer survivors. J Am Diet Assoc 2011 Dec;111(12):1844-1851. [PMC free article] [PubMed]
Denoble AE, Huffman KM, Stabler TV, Kelly SJ, Hershfield MS, McDaniel GE, Coleman RE, Kraus VR. Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation. Proc Natl Acad Sci U S A. Feb 1 2011;108(5):2088-2093. [PMC free article] [PubMed]
Feng Q, Purser JL, Zhen Z, Duncan PW. Less exercise and more TV: leisure-time physical activity trends of shanghai elders, 1998-2008. J Public Health (Oxf). 2011 Dec;33(4):543-550. [PubMed]
Golightly YM, Marshall SW, Kraus VB, Renner JB, Villaveces A, Casteel C, Jordan JM. Biomarkers of incident radiographic knee osteoarthritis: Do they vary by chronic knee symptoms? Arthritis Rheum 2011 Aug;63(8):2276-2283. [PMC free article] [PubMed]
Hall K, Pieper C, Edelman D, Yancy WS Jr, Green JB, Lum H, Peterson MJ, Sloane R, Cowper PA, Bosworth HB, Huffman KM, Cavanaugh JT, Chapman JG, Pearson MP, Howard TA, Ekelund CC, McCraw BL, Burrell JB, Taylor GA, Morey MC. Lessons learned when innovations go awry: A baseline description of a behavioral trial-the enhancing fitness in older overweight veterans with impaired fasting glucose study. Transl Behav Med 2011 Nov;1(4):573-587. [PMC free article] [PubMed]
Hayden KM, Jones RN, Zimmer C, Plassman BL, Browndyke JN, Pieper C, Warren LH, Welsh-Bohmer KA. Factor structure of the National Alzheimer’s Coordinating Centers uniform dataset neuropsychological battery: An evaluation of invariance between and within groups over time. Alzheimer Dis Assoc Disord 2011 Apr-Jun;25(2):128-137. [PMC free article] [PubMed]
Huffman KM, Pieper CF, Kraus VB, Kraus WE, Fillenbaum GG, Cohen HJ. relations of a marker of endothelial activation (s-VCAM) to function and mortality in community-dwelling older adults. J Gerontol A Biol Sci Med Sci 2011 Dec;66(12):1369-1375. [PMC free article] [PubMed]
Huffman KM, Slentz CA, Bateman LA, Thompson D, Muehlbauer MJ, Bain JR, Stevens RD, Wenner BR, Kraus VB, Newgard CB, Kraus WE. Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity. Diabetes Care 2011 Jan;34(1):174-176. [PMC free article] [PubMed]
Hybels CF, Blazer DG, Landerman LR, Steffens DC. Heterogeneity in symptom profiles among older adults diagnosed with major depression. Int Psychogeriatr 2011 Aug;23(6):906-922. [PMC free article] [PubMed]
Jones LW, Eves ND, Spasojevic I, Wang F, Il’yasova D. Effects of aerobic training on oxidative status in postsurgical non-small cell lung cancer patients: A pilot study. Lung Cancer 2011 Apr;72(1):45-51. [PMC free article] [PubMed]
Kenjale AA, Ham KL, Stabler T, Robbins JL, Johnson JL, Vanbruggen M, Privette G, Yim E, Kraus WE, Allen JD. Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease. J Appl Physiol 2011 Jun;110(6):1582-1591. [PMC free article] [PubMed]
Kuchibhatla MN, Fillenbaum GG. Trajectory classes of depression in a randomized depression trial of heart failure patients: A reanalysis of the SADHART-CHF trial. Am J Geriatr Pharmacother 2011 Dec;9(6):483-494. [PMC free article] [PubMed]
Landerman LR, Mustillo SA, Land KC. Modeling repeated measures of dichotomous data: Testing whether the within-person trajectory of change varies across levels of between-person factors. Soc Sci Res 2011 Sep 1;40(5):1456-1464. [PMC free article] [PubMed]
Lum H, Sloane R, Huffman KM, Kraus VB, Thompson DK, Kraus WE, Bain JR, Stevens R, Pieper CF, Taylor GA, Newgard CB, Cohen HJ, Morey MC. Plasma Acylcarnitines Are Associated with Physical Performance in Elderly Men. J Gerontol A Biol Sci Med Sci 2011 May;66(5):548-553. [PMC free article] [PubMed]
Nelson, AE, Chaudhary, S, Kraus, VB, Fang, F, Chen, J-C, Schwartz, TA, Shi, XA, Renner, JB, Stabler, TV, Helmick, CG, Caldwell, K, Poole, AR, Jordan, JM. Whole blood lead levels are associated with biomarkers of joint tissue metabolism in African American and white men and women: The Johnston County Osteoarthritis Project. Environ Res. 2011 Nov;111(8): 1208-1214. Minority Research Publication [PMC free article] [PubMed]
Nelson, AE, Renner, JB, Schwartz, TA, Kraus, VB, Helmick, CG, Jordan, JM. Differences in multijoint radiographic osteoarthritis phenotypes among African Americans and Caucasians: The Johnston County Osteoarthritis project. Arthritis Rheum. 2011 Dec;63(12):3843-3852. Minority Research Publication [PMC free article] [PubMed]
Ostbye T, Malhotra R, Landerman LR. Body mass trajectories through adulthood: Results from the National Longitudinal Survey of Youth 1979 Cohort (1981-2006). Int J Epidemiol 2011 Feb;40(1):240-250. [PubMed]
Pieper C, Redman L, Racette S, Roberts S, Bhapkar M, Rochon J, Martin C, Kraus W, Das S, Williamson D, Ravussin E. Development of adherence metrics for caloric restriction interventions. Clin Trials. 2011 Apr;8(2):155-164. [PMC free article] [PubMed]
Redman LM, Huffman KM, Landerman LR, Pieper CF, Bain JR, Muehlbauer MJ, Stevens RD, Wenner BR, Kraus VB, Newgard CB, Kraus WE, Ravussin E. Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women. J Clin Endocrinol Metab. 2011 Feb;96(2):E312-321. [PMC free article] [PubMed]
Sun AY, Koontz JI, Shah SH, Piccini JP, Nilsson KR Jr, Craig D, Haynes C, Gregory SG, Hranitzky PM, Pitt GS. The S1103Y cardiac sodium channel variant is associated with implantable cardioverter-defibrillator events in blacks with heart failure and reduced ejection fraction. Circ Cardiovasc Genet 2011 Apr;4(2):163-168. [PMC free article] [PubMed]
Whitson HE, Hastings SN, Landerman LR, Fillenbaum GG, Cohen HJ, Johnson KS. Black-White disparity in disability: The role of medical conditions. J Am Geriatr Soc 2011 May;59(5):844-850. Minority Research Publication [PMC free article] [PubMed]
Whitson HE, Steinhauser K, Ammarell N, Whitaker D, Cousins SW, Ansah D, Sanders LL, Cohen HJ. Categorizing the effect of comorbidity: A qualitative study of individuals’ experiences in a low-vision rehabilitation program. J Am Geriatr Soc 2011 Oct;59(10):1802-1809. [PMC free article] [PubMed]
Whitson HE, Thielke S, Diehr P, O’Hare AM, Chaves PH, Zakai NA, Arnold A, Chaudhry S, Ives D, Newman AB. Patterns and predictors of recovery from exhaustion in older adults: The cardiovascular health study. J Am Geriatr Soc 2011 Feb;59(2):207-213. [PMC free article] [PubMed]
Brummett BH, Boyle SH, Kuhn CM, Siegler IC, Williams RB. Socioeconomic status moderates associations between CNS serotonin and expression of beta2-integrins CD11b and CD11c. J Psychiatr Res 2010 Apr;44(6):373-377. [PMC free article] [PubMed]
Cavanaugh JT, Kochi N, Stergiou N. Nonlinear Analysis of Ambulatory Activity Patterns in Community-Dwelling Older Adults. J Gerontol A Bio Sci Med Sci 2010 Feb;65(2):197-203. [PMC free article] [PubMed]
Chen HC, Kraus VB, Li YJ, Nelson S, Haynes C, Johnson J, Stabler T, Hauser E, Gregory G, Kraus WE, Shah S. Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large multigenerational extended family. Arthritis Rheum. 2010 Mar;62(3):781-790. Minority Research Publication [PMC free article] [PubMed]
Chen TD, Anderson DJ, Chopra T, Choi Y, Schmader KE, Kaye KS. Poor Functional Status is an Independent Predictor of Surgical Site Infections due to Methicillin-Resistant Staphylococcus aureus in Older Adults. J Am Geriatric Soc 2010 Mar;58(3):527-532. [PMC free article] [PubMed]
Fillenbaum GG, Blay SL, Andreoli SB. Prevalence and Correlates of Functional Status in an Older Community-Representative Sample in Brazil. J Aging Health 2010 Apr;22(3):362-383. [PMC free article] [PubMed]
Fillenbaum GG, Kuchibhatla MN, Whitson HE, Batch BC,Svetkey LP, Pieper CF, Kraus WE, Cohen HJ, Blazer DG. Accuracy of self-reported height and weight in a community-based sample of older African Americans and Whites. J Gerontol A Biol Sci Med Sci 2010 Oct;65(10):1123-1129. Minority Research Publication [PMC free article] [PubMed]
Hall KSM, Crowley GM, McConnell ES, Bosworth HB, Sloane RS, Ekelund CC, Morey MC. Change in goal ratings as a mediating variable between self-efficacy and physical activity in older men. Ann of Behav Med 2010 Jun;39(3):267-273. [PMC free article] [PubMed]
Huffman KM, Hall KS, Sloane R, Peterson MJ, Bosworth HB, Ekelund CC, Pearson MP, Howard T, Pieper CF, Morey MC. Is Diabetes Associated with poorer self-efficacy and motivation for physical activity in older adults with arthritis? Scand J Rheumatol 2010;39(5):380-386. [PMC free article] [PubMed]
Huffman KM, Sloane R, Peterson MJ, Bosworth HB, Ekelund CC, Pearson MP, Howard T, Pieper CF, Morey MC. The impact of self-reported arthritis and diabetes on response to a home-based physical activity counseling intervention. Scan J Rheumatol 2010 May;39(3):233-239. [PMC free article] [PubMed]
Hybels CF, Pieper CF, Blazer DG, Fillenbaum GG, Steffens DC. Trajectories of mobility and IADL function in older patients diagnosed with major depression. Int J Geriatri Psychiatry 2010 Jan;25(1):74-81. [PMC free article] [PubMed]
Lee RH, Lyles KW, Colón-Emeric C. A review of the effect of anticonvulsant medications on bone mineral density and fracture risk. Am J Geriatr Pharmacother 2010 Feb;8(1):34-46. [PMC free article] [PubMed]
Mandelblatt JS, Sheppard VB, Hurria A, Kimmick G, Isaacs C, Taylor K, Kornblith AB, Noone A, Luta G, Tallarico M, Barry WT, Hunegs L, Zon R, Naughton M, Winer E, Hudis C, Edge SB, Cohen HJ, Muss H. Breast cancer adjuvant chemotherapy decisions in older women: the role of patient preference and interactions with physicians. J Clin Oncol 2010 Jul 1;28(19);3146-3153. [PMC free article] [PubMed]
Pavon JM, Whitson HE, Okun MS. Parkinson’s disease in women: a call for improved clinical studies and for comparative effectiveness research. Maturitas 2010 Apr;65(4):352-358. [PMC free article] [PubMed]
Peterson MJ, Morey MC, Giuliani C, Pieper CF, Evenson KR, Mercer V, Visser M, Brach JS, Kritchevsky SB, Goodpastor BH, Rubin S, Satterfield S, Simonsick ES, Health ABC Study. Walking in old age and development of metabolic syndrome: The Health, Aging, and Body Composition Study. Meta Syndr Relat Disord 2010 Aug;8(4):317-322. [PMC free article] [PubMed]
Whitson HE, Ansah D, Whitaker D, Potter G, Cousins SW, MacDonald H, Pieper CF, Landerman L, Steffens D, Cohen HJ. Prevalence and patterns of comorbid cognitive impairment in low vision rehabilitation for macular disease. Arch Gerontol Geriatr 2010 Mar-Apr;50(2):209-212. [PMC free article] [PubMed]
Zeng Y, Gu D, Purser JL, Hoenig H, Christakis N. Associations of environmental factors with elderly health and mortality in China. Am J Public Health 2010 Feb;100(2):298-305. [PMC free article] [PubMed]
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Cohen H, Harris T, Pieper C. Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderly. Am J Med 2003 Feb;114(3):180-187. [PubMed]
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Demark-Wahnefried W, Rock CL. Nutrition-related issues for the breast cancer survivor. Semin Oncol 2003 Dec;30(6):789-798. [PubMed]
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Congratulations to our 2020-2021 Maddox Awardees! Read all about them and their work here: https://sites.duke.edu/centerforaging/2020-maddox-award-announcement/
The Duke Internal Medicine Residency Program has renamed one of its weekly noon conferences, Chair’s Conference, to honor Harvey Jay Cohen, MD, Walter Kempner Distinguished Professor in the School of Medicine and former Chair of the Department of Medicine, and Director Emeritus of the Duke Aging Center.
The Duke Internal Medicine Chief Residents recognized Anthony Galanos, MD with the 2020 Eugene Stead Award for excellence in teaching.
Miriam Morey, PhD received the Paul B Magnuson Award in May 2020, which is the VA Rehabilitation Research and Development Service’s highest honor. It is given to recognize humanitarianism and dedication in service to Veterans.
Anatoliy Yashin and other Aging Center Senior Fellows and collaborators Igor Akushevich and Svetlana Ukraintseva from the Biodemography of Aging Research Unit of the Social Sciences Research Institute were honored by the journal Technometrics with the Eric Ziegel Prize for best book of the year in 2019.
Dr. Kimberly Johnson, a Pepper Center Core co-Leader and Director of the REACH Equity Center, was honored by the American Academy of Hospice and Palliative Medicine with the 2019 Richard Payne Outstanding Achievement in Diversity, Equity, and Inclusion Award for her ground-breaking work on diversity, equity and inclusion at the end of life.
Dr. Nicki Hastings, who is part of the Pepper Center and is the Director of Health Services Research & Development at the Durham VA, was honored by the Internal Medicine Program with The 2019 Joseph Greenfield Award for Research Mentoring.
My very first interaction with Duke occurred during my first year of medical school. Desperate to embark on geriatrics research in 1985 I wrote to someone asking for a copy of the OARS instrument (Older Americans Resources and Services Program famously developed at Duke to measure the impact of services on the functional status of older adults.). Yes, someone sent me a copy in the mail, this was way before e-mail and scanners or faxing were popular. When I finally arrived at Duke for fellowship training in geriatrics I was afforded the privilege of working with Gerda Fillenbaum, PhD, one of the authors of the OARS instrument. Together we embarked on exploring data collected by the Consortium to Establish a Registry for Alzheimer’s Disease. I was particularly interested in the weight changes that many clinicians witnessed in caring for these patients, in particular the tendency to lose weight. As a junior faculty member I continued to explore care for patients with dementia collaborating with Edward Levin, PhD, to understand the potential for nicotine to improve the symptoms of this disease while avoiding potential adverse effects such as weight loss.
However, my passion for academic geriatrics could not be quenched by research alone, I am very much at home at the bedside or in the clinic with older adults and I enjoy sharing this passion with learners. Dr. Robert Sullivan became one of my early clinical mentors, helping me to appreciate the value of caring for patients in the skilled nursing facility. As medical director at The Methodist Retirement Community that was located on Erwin Road, and later at the Croasdaile Village Retirement Community, I sharpened my skills and learned from patients, families and members of the interprofessional team. A Geriatric Academic Career Award allowed me to develop long-term care focused education for our geriatrics fellows, post-doctoral fellows, pharmacy residents, physical therapy residents, geropsychiatry fellows, palliative care fellows, and advanced nursing students. Although we were doing a laudable job teaching them about clinical care in this setting, The Advanced Course in Long-Term Care that resulted ensures a more nuanced curriculum regarding this care setting, in relationship to the larger health system, so our learners are poised to become leaders and change advocates.
Funding from the Reynolds Foundation has allowed me to extend myself into the arena of faculty development. Working with faculty from other institutions to develop their own curriculum in post-acute and long-term care has been a prized endeavor accomplished through the weeklong mini-fellowships that have been offered over the past 10 years. My concern for care environments that meet the needs of many of the oldest and frailest among us has led me to volunteer my time with AMDA The Society for Post-Acute and Long-Term Care Medicine. I enjoy co-directing the Futures Program that brings approximately 60 geriatrics fellows to the annual meeting to learn more about a career in medical direction. I will serve as the president of this professional organization for 2017-2018.
In the wake of health care reform, my expertise in caring for older adults with cognitive and physical disabilities, especially in post-acute and long-term care, has opened doors of opportunity. Duke Connected Care, the newly formed physician-lead Duke accountable care organization is very interested in programs and systematic changes that will improve both the quality and cost of care for older adults with complex care needs. I have been pleased to serve on the operating committee and to help establish a geriatrics advisory group. Working with Dr. Tom Owens, our Duke Health System Chief Medical Officer and his associate Laura Huffman, we have established quarterly conferences that bring together an interprofessional group of Duke leaders from our hospitals and home health care with area skilled nursing facility (SNF) leaders to gain knowledge of best practices and discuss issues of mutual concern. Concurrently, I was asked to lead a Health Optimization Program for Elders (HOPE) to improve care transitions from Duke Hospital to area SNFs. The outcomes of this pilot program have gained attention and funding for hospital-wide expansion. Also the Duke Institute for Healthcare Innovation has funded a portion of this project that will develop interactive on-line education for Duke and SNF staff to continue to improve transitions and care for vulnerable seniors in need of post-hospital rehabilitation.
I am especially blessed to have the opportunity to share my passion for providing and improving care with many Duke undergraduate students, primarily women, many of whom have been referred to me over the years by Deborah Gold, PhD, who provides the first spark for gerontology to so many Duke undergraduate students in the classes she teaches. These interactions with undergraduates and a dense network of professional connections at Duke in part provided by my spouse and fellow Duke faculty member, Leonard White, PhD, a neuroscientist, has led to a growing collaboration with two younger Duke researchers, Cassandra Germain, PhD, and Tobias Overath, PhD, also both neuroscientists. Together over the next year, we will lead a Bass Connections funded program involving three undergraduate students and two medical students to explore the scientific basis of personalized music, a currently popular intervention to improve the behavior and quality of life for older adults suffering from Alzheimer’s disease and other forms of dementia.
Duke is truly a rich environment of experimentation and change that has fueled my career as an academic geriatrician over the past 20 years and I hope to continue to make a difference not just for my own patients but for all the elders in our health care system while providing opportunity and experiences for the professional development of the passionate geriatricians and gerontologists who will eventually take my place.
Eleven years after the Duke Center for the Study of Aging and Human Development was founded, the postdoctoral research training program began. I was a fellow in the first year, and have been affiliated with the Center ever since. Being new, the program was very flexible, allowing fellows to pursue their interests without first having to submit a formal proposal. I came to it with academic qualifications in clinical and social psychology, and an interest in industrial psychology.
The initial topic I planned to examine, the social structure of a nursing home, turned out to be infeasible, since the home seemed likely to close. Based on a positive experience with an older employee of a local mortgage company (in contrast to the behavior of his younger co-worker), I decided to look at why people continue to work after retirement when they have no financial need to do so. This issue, using both new data and data already available, and with funding from Social Security’s extramural grant program and the National Institute on Aging (NIA), engaged me and my colleagues for many years, resulting in multiple publications, including a book on retirement.
Midway during this era, the Aging Center obtained funding to examine alternatives to institutionalization. Because of a conversation on my interest in institutions nearly 10 years earlier, I was invited to participate. We enjoyed the luxury of a planning year, during which a thoroughly multidisciplinary group of Duke faculty came together, learned each other’s language, and developed the OARS (Older Americans Resources and Services) program. This program included a multidimensional functional assessment and service use questionnaire, together with a means for classifying people to determine need, evaluate programs, and make policy decisions regarding service allocation. Importantly, we assessed the reliability and validity of the OARS questionnaire. Consequently, the GAO (General Accounting [now Accountability] Office), interested in determining the impact of government services, selected the OARS questionnaire for its longitudinal study of Cleveland elderly.
OARS continues to be used widely in the U.S. and abroad (with translations into multiple languages), to ascertain both population and individual clinical status, determine service needs, and assess program impact. Interest abroad has resulted in unexpected outcomes. On one occasion (before the days of e-mail), a physician from Brazil, studying in the UK, requested OARS information. Since I was going to London, I took the materials with me to save him postage costs. We met, found much in common, he translated OARS into Portuguese, ran a survey, analyzed the data, and then developed the first course on aging in Brazil. I was invited to speak. While there I met a psychiatrist who determined the suitability of one of the OARS scales as a measure of depression in Brazil. After a lapse of 15-20 years contact was renewed. We have been writing papers together ever since, analyzing data from Brazil.
Involvement with OARS had additional consequences – participation in the 10-year Duke Established Program for Epidemiologic Studies of the Elderly, which led to determining the incidence and prevalence of dementia in older African Americans and Whites (no significant differences were found); working with the World Health Organization and the Pan American Health Organization to develop functional assessments of the elderly, used in major international surveys; and becoming the project director of the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD), which started in 1985.
CERAD, funded by the NIA, was mandated to develop a uniform set of measures to assess Alzheimer’s disease, for use in all NIA-funded Alzheimer’s Disease Centers, a move which permitted aggregation of data. The most broadly used measures continue to be the clinical/neuropsychological battery, neuropathology assessment, and Behavior Rating Scale for Dementia, but others are also available. CERAD measures have been translated into many languages, and norms developed. In addition to individual clinical use, CERAD has been used in epidemiological surveys to ascertain the prevalence and incidence of dementia, and in pharmaceutical trials.
Finally, I am also a member of the Duke Pepper Older Americans Independence Center, responsible for arranging monthly research seminars, and engaged in studies of obesity and health service use.
When I first came to Duke, both administrators and faculty offered an open door. Everyone was willing to offer help and advice. I learned from this, and have ever since tried to do the same. My feeling is that information is not information if it is not shared. For me, the Aging Center has been a welcome home, where members try to take care of each other. My initial physical introduction to the Aging Center was accidental – no office space was available in the Department of Psychology. For me, that lack was serendipitous.
For information on CERAD, and CERAD measures and data, go to: cerad.mc.duke.edu
For information on the OARS program and measures click here.
Fillenbaum GG. The wellbeing of the elderly: approaches to multidimensional assessment. Geneva: WHO Offset Publication No. 84, 1984.
Fillenbaum GG. Multidimensional functional assessment of older adults: the Duke Older Americans Resources and Services procedures. Originally published by Lawrence Erlbaum Associates, Hillsdale, NJ, 1988; now only available from the Duke Aging Center.
Fillenbaum GG, van Belle G, Morris JC, Mohs RC, Mirra SS, Davis PC, Tariot PN, Silverman JM, Clark CM, Welsh-Bohmer KA, Heyman A. CERAD (Consortium to Establish a Registry for Alzheimer’s Disease): The first 20 years. Alzheimer’s and Dementia: The Journal of the Alzheimer’s Association, 2008, 4(2), 96-109. Palmore EB, Burchett BM, Fillenbaum GG, George LK, Wallman LM. Retirement: Causes and consequences. Springer Publishing Co., New York, 1986.
Please take some time to view the History of the Center, compiled by George L. Maddox, Ph.D., below in whole and in its parts.
EXCELLENCE IN THE CARE OF AGING
The Center for the Study of Aging and Human Development was one of five centers for aging research established by the Surgeon General of the United States in 1955. It is the only continuously funded member of the original group. With more than 126 Faculty (Senior Fellows) and core staff members garnering and more than $20 million in annual age-related research funding, it remains a vital national resource for the study of aging. Current research includes studies of age-related functional decline and dysmobility, genomic, proteonic and metabolomic biomarkers of aging, exercise, osteoporosis, Alzheimer’s disease, cancer and aging, viral diseases of aging, depression in later life, caregiver stress, and religion/spirituality and health. The Center also is involved in an ambitious program designed to identify and educate future geriatricians.
Duke’s research and teaching programs in geriatrics are among the nation’s oldest. Geriatric Medicine at Duke has been a major strength of the Aging Center since 1984 with the creation of the Geriatric Division in the Department of Medicine and the Center. The Division of Geriatrics has distinguished itself as a leader in clinical care, research, and education. This sustained success is due in large part to its visionary leadership and abundant resources, including grants to the Aging Center such as the Claude D. Pepper OAIC and Hartford Center of Excellence. The VA Medical Center also hosts a Geriatrics Research, Education, and Clinical Center which is closely integrated with the Center. The Division’s Geriatrics Fellowship Training Program has committed itself to placing its best trainees in leadership positions around the nation. We count numerous division chiefs and program directors among our former fellows and junior faculty.
Until recently, most Americans regarded aging as inevitable and undesirable. Growing older was seen as a process over which individuals had little control, much less as something that could be done well. Old age–the trip “over the hill”–was something to postpone for as long as possible.
But as the bulk of our nation’s population reaches their middle years, aging is being regarded with positive interest. Americans want to know how to live longer, healthier and more productive lives. They want to plan for retirement and keep their independence for as long as possible. In other words, they want to age well.
THE CENTER’S PAST
The Duke Center for the Study of Aging and Human Development has been studying successful aging–and applying the results of its research–for more than 50 years (see History of the Center). Long before “aging” became a topic of conversation and a national concern, far-sighted academicians at Duke University documented and understood the implications of an aging population. The leaders were men and women whose distinction is now recognized nationally and internationally, including biochemist Philip Handler, PhD, demographer Joseph Spengler, PhD, economist Juanita Kreps, PhD, psychiatrist Ewald W. Busse, MD, and Duke Chancellor William Anlyan, MD.
They were backed by an equally progressive university administration that chartered a university council on aging in 1955 to promote and coordinate multidisciplinary research, training and service. Two years later, the US Public Health Service designated the Duke center as one of five regional resource centers on aging. The Duke Center for the Study of Aging and Human Development is the oldest continually-funded member of the original group.
The center’s first initiatives included the Duke Longitudinal Studies, a 20-year project begun in 1956 that monitored the physical, mental, social and economic status of approximately 800 older adults. These studies, which received the 1983 Sandoz International Prize for multidisciplinary research in aging, documented the capacity of older adults to age well, helping revolutionize thinking about human aging. In 1975, the Older Americans Resources and Services (OARS) Program developed the first comprehensive technique for assessment of functional impairment in the elderly. OARS methods, updated to reflect changes in the aging population, still are used in hundreds of research studies and geriatric clinics across the country. Duke’s Geriatric Evaluation and Treatment (GET) Clinic, opened in 1967, continues to serve older adults from throughout the southeastern United States. Since 1988 the Center’s Long Term Care Resources Program has assisted North Carolina in developing and implementing sound public policies for serving older adults and their families in the long term.
LEADERSHIP IN AGING
Leadership in Aging has been one of the hallmarks of the Duke Center for the Study of Aging and Human Development. The center has produced six Presidents of The Gerontological Society of America: Ewald W. Busse, MD, Carl Eisdorfer, MD, George L. Maddox, PhD, Linda K. George, PhD, Harvey Jay Cohen, MD and Lisa Gwyther, MSW. Three center scholars have served as President of the American Geriatrics Society: Ewald W. Busse, MD, Dan G. Blazer, MD, PhD, and Harvey Jay Cohen, MD. At the international level, Dr. Busse served as President, and Dr. Maddox as Secretary General/Vice President of the International Association of Gerontology, 1985-89. These individuals and many others have held important offices in the most prestigious organizations in gerontology and geriatrics.
THE CENTER TODAY AND TOMORROW
Under the leadership of Director Heather Whitson, MD, MHS, the Duke center continues to serve as a national resource for information about aging and as a training ground for future generations of researchers, teachers, practitioners and planners
Duke researchers understand that the growing number of older adults will have a significant impact on our society’s arrangements for income maintenance, health care, social services, housing and transportation. Studies being conducted at Duke today already are addressing the complex health problems of a longer-lived population, and developing programs that will enable the elderly to receive care while maintaining their independence for as long as possible.
The center plans to initiate and expand its aging research in several areas in the future:
- Cellular and molecular biology of aging
- Interventions to enhance longevity
- Health care and health services utilization
- Cardiovascular disease and cancer
- Family relationships in later life
- Improving disability for osteoporosis and Pagets disease of bone
- Risk factors for chronic disease and mental illness
- The economic status of older adults
We invite interested researchers and colleagues at both Duke and other institutions to join in the collaboration.