Dr. Patrick Knox

Recent Blogs »

• Building Effective Hybrid Rehabilitation Programs: Clinical, Operational, and Technological Considerations

  By: Chad E. Cook, PT, PhD, FAPTA Background: Over the past several years, I have served on Daniel Harvey’s PhD dissertation committee. His work centers…

• Using MCID for Between‑Group Comparisons Is a Methodological Mistake

  By: Chad E Cook, PT, PhD, FAPTA Background: In clinical research, especially in orthopedics, sports medicine, and rehabilitation, the minimally clinically important difference (MCID) has…

• N-of-1 Trials. Are They Appropriate for Evaluating Physical Therapy Interventions?

  By: Chad E. Cook, PT, PhD, FAPTA Background: On this Center of Excellence website, we’ve previously highlighted two key points: (1) individuals do not respond…

• Why Patients Rapidly Change After Initiating Treatment: What We Think We Know and What We Likely Don’t

  By: Chad Cook, PT, PhD, FAPTA Background: The completion of our SS‑MECH trial [1] in the fall of 2025 marked the 20th clinical trial for…

• Risk Stratification versus Risk Adjustment: Both are Important but They are Not the Same Thing

  By: Chad E Cook, PT, PhD, FAPTA Background: In 2011, I was part of a team of researchers who looked at very large datasets and…

• What Really Happens When We Use Manual Therapy? A Fresh Look at the Mechanisms Behind Hands-On Approaches

  Authors: Damian Keter DPT, PhD, Chad Cook PT, PhD, FAPTA Manual therapy (MT) has been part of musculoskeletal care for centuries, yet one question continues…