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Structure and Dynamics of Nucleic Acids

“Everything that living things do can be understood in terms of the jiggling and wiggling of atoms” —Richard Feynman.

Lab News

03.2022 Megan Kelly successfully defends her Ph.D.
02.2022 Megan Kelly is selected as the recipient of the 2021-2022 Chancellor’s Award for Research Excellence
06.2021 Megan, Laura and Henry are the winners of the Inaugural RNA Society Arts and Music Competition! See more.
06.2021 Atul Rangadurai is the recipient of the Canadian Institutes of Health Research (CIHR) fellowship.
12.2020 Hashim is elected as one of the ISMAR Fellows.
11.2020 Hashim is named one of the 2021 Class of Fellows of the Biophysical Society.
01.2020 Hashim is the recipient of the 2020 National Academy of Science Award in Molecular Biology! See more.

Recent Publications

04.2022 Atul, Honglue, Yu Xu et al published a paper entitled “Measuring thermodynamic preferences to form non-native conformations in nucleic acids using UV melting” in PNAS
12.2021 Honglue et al published a paper entitled “Revealing A-T and G-C Hoogsteen base pairs in stressed protein-bound duplex DNA”  in Nucleic Acids Research
11.2020 Honglue and Atul et al published a paper entitled “Rapid and accurate determination of atomistic RNA dynamic ensemble models using NMR and structure prediction” in Nature Communications
10.2020 Ariel, Honglue and Atul et al published a paper entitled “DNA mismatches reveal conformational penalties in protein-DNA recognition” in Nature See more.