Frohlich KM, Weintraub SF, Bell JT, Todd GC, Väre VYP, Schneider R, Kloos ZA, Tabe ES, Cantara WA, Stark CJ, Onwuanaibe UJ, Duffy BC, Basanta-Sanchez M, Kitchen DB, McDonough KA, Agris PF. (2019) Discovery of Small-Molecule Antibiotics against a Unique tRNA-Mediated Regulation of Transcription in Gram-Positive Bacteria. ChemMedChem. 14(7):758-769. doi: 10.1002/cmdc.201800744. Epub 2019 Mar 1.
Elliott BA, Ho HT, Ranganathan SV, Vangaveti S, Ilkayeva O, Abou Assi H, Choi AK, Agris PF, Holley CL. (2019) Modification of messenger RNA by 2′-O-methylation regulates gene expression in vivo. Nat Commun. 10(1):3401. doi: 10.1038/s41467-019-11375-7
Vangaveti S, Cantara WA, Spears JL, DeMirci H, Murphy FV 4th, Ranganathan SV, Sarachan KL, Agris PF. A structural basis for restricted codon recognition mediated by 2-thiocytidine in tRNA containing a wobble position inosine. J Mol Biol. 2020 432(4):913-929
Swinehart W, Deutsch C, Sarachan KL, Luthra A, Bacusmo JM, de Crécy-Lagard V, Swairjo MA, Agris PF, Iwata-Reuyl D. Specificity in the biosynthesis of the universal tRNA nucleoside N6-threonylcarbamoyl adenosine (t6A)-TsaD is the gatekeeper. RNA. 2020 Sep;26(9):1094-1103. doi: 10.1261/rna.075747.120. Epub 2020 May 8. PMID: 32385138
Seyler TM, Moore C, Kim H, Ramachandran S, Agris PF. A New Promising Anti-Infective Agent Inhibits Biofilm Growth by Targeting Simultaneously a Conserved RNA Function That Controls Multiple Genes. Antibiotics (Basel). 2021 Jan 4;10(1):41. doi: 10.3390/antibiotics10010041. PMID: 33406640; PMCID: PMC7824582.
Narendran A, Vangaveti S, Ranganathan SV, Eruysal E, Craft M, Alrifai O, Chua FY, Sarachan K, Litwa B, Ramachandran S, Agris PF. Silencing of the tRNA Modification Enzyme Cdkal1 Effects Functional Insulin Synthesis in NIT-1 Cells: tRNALys3 Lacking ms2- (ms2t6A37) is Unable to Establish Sufficient Anticodon:Codon Interactions to Decode the Wobble Codon AAG. Front Mol Biosci. 2021 Feb 9;7:584228. doi: 10.3389/fmolb.2020.584228. PMID: 33634165; PMCID: PMC7900539.
