Research Team

CO-PRINICIPAL INVESTIGATORS

Rima Kaddurah-Daouk

Duke University

Professor in the Departments of Psychiatry and Medicine at Duke University Medical Center. She made seminal contributions to the development of the metabolomics field. She established and leads several large consortia including the Alzheimer’s Disease Metabolomics Consortium (ADMC).

Rob Knight

UC San Diego

 

Professor at the University of California San Diego. He is co-founder of the American Gut Project and the Earth Microbiome Project specializing in the development of computational and lab techniques to define human, animal, and environmental microbes.

Sarkis Mazamanian

CalTech

 

Professor of Microbiology at the California Institute of Technology. He is a medical microbiologist whose research focuses on the gut-brain axis of communication. His lab was the first to demonstrate that intestinal bacteria direct universal development of the immune system, and control complex behaviors in preclinical models.

INVESTIGATORS

Gabi Kastenmüller

Helmholtz Zentrum München

Acting director of the Institute of Bioinformatics and Systems Biology. Her focus is on human chemical individuality and its effects in health, disease, and treatment, metabolome and genome associations, and bioinformatic tools and databases for metabolomics data analysis.

Matthias Arnold

Helmholtz Zentrum München

Adjunct Assistant Professor at Duke University. Bioinformatician and lead analyst on metabolomics projects at the Helmholtz Zentrum München.  Specializes in metabolomics data and its integration with multi-omics into networks.

Jan Krumsiek

Weill Cornell Medicine

Assistant Professor of Physiology and Biophysics and Computational Genomics. He develops and applies new analytical methods, including machine learning and bioinformatics, to metabolomics and multi-omic data analysis.

Thomas Hankemeier

Leiden University

Professor of Analytical BioSciences at the LACDR, PI of the Analytical BioSciences and Metabolomics group, and the Division of Systems Biomedicine and Pharmacology Chair.  His research involves innovative analytical tools for metabolomics driven systems biology in personalized health.

Ines Thiele

NUI Galway

PI of the Molecular Systems Physiology group. She pioneered models and methods allowing large scale computational modelling of the human gut microbiome and its metabolic effect on human metabolism. Her research aims to improve the understanding of how diet influences human health.

Pieter Dorrestein

UC San Diego

Professor  of Pharmacy and Pharmaceutical Sciences,  Director of the Collaborative Mass Spectrometry Innovation Center, and Co-Director of the Institute for Metabolomics Medicine. His lab is developing new mass spectrometry-based methods to explore the chemistry of microbes and the human microbiome.

Tatiana Foroud

NCRAD

Professor of Medical and Molecular Genetics where she chairs the department at Indiana University.  She is also a geneticist and leader in dementia research, and the head of NCRAD, the NIH funded National Repository for Alzheimer’s Disease and Related Dementias.

Janet Jansson

PNNL

Microbial ecologist and Chief Scientist for Biology in the Biological Sciences Division and a Laboratory Fellow at the Pacific Northwest National Laboratory (PNNL). Her study of microbial communities includes the human microbiome, and the impact of diet, host genetics and disease on microbial functions.

Emeran Mayer

UCLA

Professor of Medicine, Physiology, and Psychiatry. Director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience. He is recognized as a leading investigator of brain gut microbiome interactions in GI disorders, including functional and inflammatory bowel disorders and obesity.

Andy Saykin

Indiana University

Professor of Radiology; Director of the Indiana ADRC and the Center for Neuroimaging. He uses brain imaging and genomic methods to study mechanisms of memory dysfunction and treatment response in neurological and psychiatric disorders and is a world expert on neuroimaging and diagnosing AD.

Kwangsik Nho

Indiana University

Associate Professor of Radiology & Imaging Sciences. His research expertise is in the areas of bioinformatics, imaging informatics, and medical informatics. He integrates omics data to perform next generation sequence analysis to gain deeper understanding of the pathogenesis of complex diseases.

Murali Doraiswamy

Duke University

Professor of Medicine & Psychiatry & Behavioral Sciences; Director of the Neurocognitive Disorders Program and a clinical trials unit involved in the development of many modern diagnostic tests, apps, algorithms, and therapeutics.

Suzanne Craft

Wake Forest

Professor of Gerontology and Geriatric Medicine. Dr. Craft’s research has centered around Alzheimer’s disease, Cognitive disorders, dementia, diet, and insulin resistance. Leads the Wake Forest AD Core Center and the BEAT-AD clinical diet trial which examines the effects of a modified Mediterranean-Ketogenic Diet on AD biomarkers and cognition.

Cornelia van Duijn

Oxford University

Professor of Epidemiology at Nuffield Department of Population Health and a Fellow of St Cross College, Oxford.Her research at the Oxford Big Data Institute focuses on large scale omics studies of Alzheimer’s Disease and other neurodegenerative disorders.

Robin Voigt-Zuwala

Rush University

Associate Professor, Department of Internal Medicine. Research areas include the study of the intestinal microbiome in cognition and Alzheimer's disease.

Ali Keshavarzian

Rush University

Professor, Departments of Internal Medicine, Pharmacology, and Molecular Physiology. Director of the Division of Digestive Diseases & Nutrition & the Institute for Advanced Study of the Gut, Chronobiology & Inflammation. He studies the impact of environmental factors on intestinal barrier function host/microbe interaction that promote intestinal and systemic (gut-derived) inflammation.