2023
The C. elegans anchor cell: A model to elucidate mechanisms underlying
invasion through basement membrane
Kenny-Ganzert, I. W., & Sherwood, D. R. (2023). The C. elegans anchor cell: A model to elucidate mechanisms underlying invasion through basement membrane. Seminars in Cell & Developmental Biology. https://doi.org/10.1016/j.semcdb.2023.07.002 pdf
Differential production rates of cytosolic and transmembrane GFP reporters in C. elegans L3 larval uterine cells
Kenny-Ganzert, I; Chi, Q; Sherwood, D (2023). Differential production rates of cytosolic and transmembrane GFP reporters in C. elegans L3 larval uterine cells. microPublication Biology. 10.17912/micropub.biology.000813 pdf
The Caenorhabditis elegans anchor cell transcriptome: ribosome biogenesis drives cell invasion through basement membrane
Costa, D. S., Kenny-Ganzert, I. W., Chi, Q., Park, K., Kelley, L. C., Garde, A., Matus, D. Q., Park, J., Yogev, S., Goldstein, B., Gibney, T. V., Pani, A. M., & Sherwood, D. R. (2023). The caenorhabditis elegans anchor cell transcriptome: Ribosome biogenesis drives cell invasion through basement membrane. Development, 150(9). https://doi.org/10.1242/dev.201570 pdf
Reciprocal discoidin domain receptor signaling strengthens integrin adhesion to connect adjacent tissues
Park, K., Jayadev, R., Payne, S. G., Kenny-Ganzert, I. W., Chi, Q., Costa, D. S., Ramos-Lewis, W., Thendral, S. B., & Sherwood, D. R. (2023). Reciprocal discoidin domain receptor signaling strengthens integrin adhesion to connect adjacent tissues. eLife, 12. https://doi.org/10.7554/elife.87037 pdf
Hemicentin mediated type IV collagen assembly strengthens juxtaposed basement membrane linkage
Gianakas, C. A., Keeley, D. P., Ramos-Lewis, W., Park, K., Jayadev, R., Kenny, I. W., Chi, Q., & Sherwood, D. R. (2022). Journal of Cell Biology, 222(1). https://doi.org/10.1083/jcb.202112096 pdf
2022
A light sheet fluorescence microscopy protocol for Caenorhabditis elegans larvae and adults
Smith, J. J., Kenny, I. W., Wolff, C., Cray, R., Kumar, A., Sherwood, D. R., & Matus, D. Q. (2022). https://doi.org/10.1101/2022.08.05.503008 pdf
Visualizing cytoplasmic ATP in C. elegans larvae using PercevalHR.
Garde, A., & Sherwood, D. R. (2022). STAR Protocols, 3(2), 101429. https://doi.org/10.1016/j.xpro.2022.101429 pdf
A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations.
Jayadev, R., Morais, M. R., Ellingford, J. M., Srinivasan, S., Naylor, R. W., Lawless, C., Li, A. S., Ingham, J. F., Hastie, E., Chi, Q., Fresquet, M., Koudis, N.-M., Thomas, H. B., O’Keefe, R. T., Williams, E., Adamson, A., Stuart, H. M., Banka, S., Smedley, D., Sherwood, D. R., & Lennon, R. (2022). Science Advances, 8(20). https://doi.org/10.1126/sciadv.abn2265 pdf
Localized glucose import, glycolytic processing, and mitochondria generate a focused ATP burst to power basement membrane invasion.
Garde, A., Kenny, I. W., Kelley, L. C., Chi, Q., Mutlu, A. S., Wang, M. C., & Sherwood, D. R. (2022). Developmental Cell, 57(6). https://doi.org/10.1016/j.devcel.2022.02.019 pdf
2021
Basement membrane remodeling guides cell migration and cell morphogenesis during development.
Sherwood, D.R. (2021). Current Opinion in Cell Biology, 72, 19–27. https://doi.org/10.1016/j.ceb.2021.04.003. pdf
2020
Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche
Gordon, K.L., Zussman, J.W., Li, X., Miller, C., Sherwood, D.R. (2020). eLife 2020;9:e56383 DOI: 10.7554/eLife.56383. pdf
eLife Insight-More than just a pool
eLife Digest: To egg or not to egg
Comprehensive endogenous tagging of basement membrane components reveals dynamic movement within the matrix scaffolding
Keeley, D.P., Hastie, E., Jayadev R., Kelley, L.C., Chi, Q., Payne, S.G., Jeger, J.L., Hoffman, B.D., Sherwood, D.R.(2020). Dev Cell. pdf
Developmental Cell Previews-Mobilizing the Matrix
Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues
Lin MH, Pope BD 3rd, Sasaki T, Keeley DP, Sherwood DR, Miner JH. Dev Dyn. 2020;249(6):775-788. doi:10.1002/dvdy.159 pdf
2019
A scalable CURE Using a CRISPR/Cas9 Fluorescent Protein Knock-In Strategy in Caenorhabditis elegans
Hastie E., Sellers R., Valan B., Sherwood D.R. (2019). J Microbiol Biol Educ. 2019 Dec 18;20(3):20.3.60. pdf
α-Integrins dictate distinct modes of type IV collagen recruitment to basement membranes
Jayadev R., Chi Q., Keeley, D.P., Hastie, E.L., Kelley, L.C.,Sherwood D.R. (2019). J. Cell Biol., Aug 6. pii cb.201903124. doi: 10.1083/jcb.201903124. pdf
MANF deletion abrogates early larval Caenorhabditis elegans stress response to tunicamycin and Pseudomonas aeruginosa
Hartman J.H., Richie C.T., Gordon K.L., Mello D.F.,, Castillo P., Zhu A., Wang Y., Hoffer B.J., Sherwood D.R., Meyer J.N.,, Harvey B.K. (2019). Eur J Cell Biol. May 21. pii: S0171-9335(18)30348-0. doi: 10.1016/ j.ejcb.2019.05.002. PMID:31138438. pdf
Ectopic germ cells can induce niche-like enwrapment by neighboring body wall muscle
Gordon K.L., Payne, S.G., Linden-High L.M., Pani, A.M., Goldstein, B.,Hubbard, J.A., Sherwood. D.R. (2019). Curr Biol. Mar 4;29(5):823-833.e5. doi: 10.1016/j.cub .2019.01.056. Epub 2019 Feb 21.PMID: 30799241. pdf
Current Biology Dispatch-Kelley and Cram
Adaptive F-actin polymerization and localized ATP production drive basement membrane invasion in the absence of MMPs
Kelley, L.C., Hastie E., Cáceres, R., Chi. Q., Schindler A.J., Jiang Y., Matus, D.Q., Julie Plastino J., and Sherwood, D.R. (2019). Dev Cell. Jan 23. pii: S1534-5807(18)31086-4. doi: 10.1016/j.devcel.2018.12.018 pdf
Nature Reviews Molecular Cell Biology-Forcing Through Barriers
Dev Cell Preview-Invasion by Force. Nikolau and Machesky
2018
Forces drive basement membrane invasion in Caenorhabditis elegans
Cáceresa, R., Bojanalaa N., Kelley, L.C., Dreiere J., Manzia, J., Federicoa, F.D., Chi, Q., Rislera, T.,, Testae, I., Sherwood, D.R.,, Plastino, J. (2018). Proc Natl Acad Sci U S A. Nov 6;115(45):11537-11542. doi: 10.1073/pnas.1808760115. Epub 2018 Oct 22. PMID: 30348801. pdf
Non-selective autophagy reduces mitochondrial content during starvation in Caenorhabditis elegans
Hibshman J.D., Leuthner T.C., Shoben C., Mello D.F., Sherwood D.R., Meyer J.N., Baugh L.R. (2018). Am J Physiol Cell Physiol. Aug 22. doi: 10.1152/ajpcell.00109.2018. PMID:30133321 pdf
Tissue linkage through adjoining basement membranes: The long and the short term of it
Keeley D.P. and Sherwood D.R. (2018). Matrix Biol. May 24. pii: S0945-053X(18)30190-2. doi: 10.1016/j.matbio.2018.05.009. [Epub ahead of print]. pdf
Swimming Exercise and Transient Food Deprivation in Caenorhabditis elegans Promote Mitochondrial Maintenance and Protect Against Chemical-Induced Mitotoxicity
Hartman J.H., Smith L. L., Gordon K.L., Laranjeiro R., Driscoll M.,Sherwood D.R., Meyer J.N. (2018). (2018) Sci Rep. May 29;8(1):8359. doi: 10.1038/s41598-018-26552-9. pdf
Invading, Leading and Navigating Cell in Caenorhabditis elegans: Insights into Cell Movement In Vivo
Sherwood D.R. and Plastino J. (2018). Genetics Jan;208(1):53-78. doi: 10.1534/genetics.117.300082. pdf
2017
Cell invasion in vivo via rapid exocytosis of a transient lysosome-derived membrane domain
Naegeli, K.M., Hastie, E.L., Garde, A., Wang Z., Keeley D.P., Gordon K.L., Pani A.M., Kelley L.C., Morrisey, M.A., Chi.Q., Goldstein.,B, Sherwood D.R. (2017). Dev Cell. Nov 20;43(4):403-417 pdf
Shah Wang and Ken Yamada Developmental Cell Preview
Identification of regulators of germ stem cell enwrapment by its niche in C. elegans
Linden, L.M., Gordon, K.L., Pani, A.M., Payne, S.G., Garde A., Burkholder, D., Chi Q., Goldstein, B., Sherwood, D.R. (2017). Dev Biol. Sep 1;429(1):271-284. doi: 10.1016/ j.ydbio. 2017.06.019. pdf
Live-cell confocal microscopy and quantitative 4D image analysis of anchor cell invasion through the basement membrane in C. elegans
Kelley, L.C., Wang, Z., Hagedorn, E.J., Wang, L., Shen W., Lei, S., Johnson, S.A.,, Sherwood, D.R. (2017). Nat Protoc. Oct;12(10):2081-2096. doi: 10.1038/nprot.2017.093. pdf
Morphogenesis: Shaping Tissues through extracellular force gradients
Jayadev R. and Sherwood D.R. (2017). Curr Biol. Sep 11;27(17):R850-R852. doi: 10.1016/j.cub.2017.07.040. pdf
Breaching and opening basement membrane barriers: the anchor cell leads the way
Keeley, D.P., and Sherwood, D.R. (2017). Extracellular matrix in tumor biology, pp 91-115 Springer Nature. pdf
Primer: Basement Membranes
Jayadev R. and Sherwood D.R. (2017). Curr Biol. Mar 20;27(6):R207-R211. doi: 10.1016/j.cub.2017.02.006. pdf
2016
Boundary cells restrict dystroglycan trafficking to control basement membrane sliding during tissue remodeling
McClatchey, S.T.H., Wang Z., Linden, L.M., Hastie, E.L., Wang, L., Shen, W., Chen, A., Chi, Q., Sherwood, D.R. (2016). eLIFE. Sep 23;5. pii: e17218. pdf
Sculpting Tissues by Fibrils
Jayadev R. and Sherwood D.R. (2016). Dev Cell. Jul 11;38(1):1-3. pdf
A new front in cell invasion: The invadopodial membrane
Hastie, E.L. and Sherwood, D.R. (2016). Eur J Cell Biol. 2016 Jun 24. S0171-9335(16)30105-4. pdf
SPARC promotes cell invasion in vivo by decreasing type IV collagen levels in the basement membrane
Morrissey, M.A., Jayadev, R., Miley, G.R., Blebea, C.A., Chi, Q., Ihara, S., Sherwood, D.R. (2016). PLoS Genet. 12(2): e1005905. pdf
Sparking ECM Interview with Meghan/Journal Coverage
A sensitized screen for genes promoting invadopodia function in vivo: CDC-42 and Rab GDI-1 direct distinct aspects of invadopodia formation
Lohmer, L.L, Clay, M.R., Naegeli, K.M., Chi, Q., Ziel, J.W., Hagedorn, E.J., Park, J.E., Jayadev, R., Sherwood, D.R. (2016). PLoS Genet.. Jan 14;12(1):e1005786. pdf
Understanding images how do cells make invasive feet
2015
Invasive cell fate requires G1 cell-cycle arrest and histone deacetylase-mediated changes in gene expression
Matus, D.Q., Lohmer, L.L., Kelley, L.C., Schindler, A.J., Korhman, A.Q., Barkoulas, M., Zhang, W., Chi, Q and Sherwood, D.R. (2015). Dev Cell. Oct. 26; 35, 162–174. pdf
Developmental Cell Preview. An arresting story about basement membrane invasion. pdf
Imaging the Cell
Meeting Report-Imaging the Cell (2015). J. of Cell Sci. Nov. 1; 128(21): 3843-7. pdf
Basement Membranes in the Worm: A Dynamic Scaffolding that Instructs Cellular Behaviors and Shapes Tissues
Clay, M.R. and Sherwood D.R. (2015). Current Topics in Membranes. Sep 12; 76:1-37. pdf
RAB-10-dependent membrane transport is required for dendritic arborization
Zou, W., Yadav, S., Devault, L., Jan, Y.N., Sherwood, D.R. (2015). PLOS Genet. Sep 22; 11(9): e1005484. pdf
A developmental biologists “outside-the-cell” thinking
Sherwood, D.R. (2015). J. Cell Biol. Aug 3; 210(3): 369-372. pdf
The unfolded protein response is required for dendrite morphogenesis
Wei, X., Howell, A.S., Dong, X., Taylor, C.A., Cooper, R.C., Zhang, J., Zou, W., Sherwood, D.R., Shen, K. (2015). eLIFE, 4:e06963. pdf
An active role for basement membrane assembly and modification in tissue sculpting
Morrissey, M. A. and Sherwood, D.R. (2015). J. Cell Science, 128, 1–8 doi:10.1242/jcs.168021. pdf
2014
Should I stay or should I go? Identification of novel nutritionally regulated developmental checkpoints in C. elegans
Schindler, A.J. and Sherwood, D.R. (2014). Worm 3:4, e979658. pdf
Repurposing an endogenous degradation system for rapid and targeted protein depletion of C. elegans proteins
Armenti, S.T., Lohmer, L.L, Sherwood, D.R., and Nance, J. Development. 141:1-8 doi.1242/dev.115048.
B-Link: A hemicentin, plectin, integrin-dependent adhesion system that links tissues by connecting adjacent basement membranes
Morrissey, M. A., Hagedorn, E. J., McClatchey, S. T. H., Chi, Q., Hall, D. H., Sherwood, D. R. (2014). Dev Cell. Nov 10; 31(3): 319-331. pdf supplemental info
MIG-10 (Lamellipodin) stablizes invading cell adhesion to basement membrane and is a negative transcriptional target of EGL-43 in C. elegans
Wang, L., Shen, W., Lei, S., Matus, D., Sherwood, D., Wang, Z. (2014). Biochem Biophys Res Commun. 2014 Sep 26;452(3):328-33. pdf
UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity
Wang, Z., Linden, L., Naegeli, K., Ziel, J. W., Chi, Q., Hagedorn, E. J., Savage, N. S.,Sherwood, D. R. (2014). Journal of Cell Biology Sep 1;206(5):619-33. pdf
In focus feature by Ben Short at JCB:pdf
Duke today: Scientist Uncover Navigation System
Dispatch, Current Biology 3 November 2014, 24(21):R1050-2. pdf
Cell division and targeted cell cycle arrest opens and stabilizes basement membrane gaps
Matus, D. Q., Chang, E., Makohon-Moore, S., Hagedorn, M., Sherwood, D. R. (2014). Nature Commun. Jun 13;(5):4184. pdf supplemental materials
Identification of late larval stage developmental checkpoints in Caenorhabditis elegans regulated by Insulin/IGF and steroid hormone signaling pathways
Schindler, A. J., Baugh, L. R., Sherwood, D. R. (2014). PLoS Genet. Jun 19;10(6):e1004426. pdf
The Scientist
BBC Nature News feature
Science Daily Feature
In situ imaging in C. elegans reveals developmental regulation of microtubule dynamics
Lacroix B., Bourdages K. G., Dorn J. F., Ihara S., Sherwood D. R., Maddox P. S., Maddox A. S. (2014). Dev Cell. Apr 28; 29(2):203-16. pdf
Invadopodia and basement membrane invasion in vivo
Lohmer, L. L., Kelley, L. C., Hagedorn, E. J., Sherwood, D. R. (2014). Cell Adh Migr.;8(3):246-55. pdf
ADF/cofilin promotes invadopodial membrane recycling during cell invasion in vivo
Hagedorn E. J*., Kelley, L. C*., Naegeli, K. M., Wang, Z., Chi, Q., Sherwood, D.R. (2014). J Cell Biol. Mar 31; 204(7): 1209-18. pdf *These authors contributed equally
Biobytes Feature
MIG-10 (Lamellipodin) has netrin independent functions and is a FOS-1A transcriptional target during anchor cell invasion in C. elegans
Wang, Z., Chi, Q., Sherwood, D.R. (2014). Development. 141:134-1353. pdf
Traversing the basement membrane in vivo: a diversity of strategies
Kelley, L. C., Lilley-Lohmer, L., Hagedorn, E. J., Sherwood, D. R. (2014). Journal of Cell Biology. 204 (3). 291–302. pdf
2013
The Netrin Receptor DCC Focuses Invadopodia Driven Basement Membrane Transmigration in vivo
Hagedorn E. J., Ziel J.W., Morrissey M. A., LindenL.M., Wang Z, Chi Q, Johnson S. A., Sherwood, D. R. (2013). Journal of Cell Biology, 10; 201(6): 903-13. pdf
Biosights Feature with Ben Short from JCB
Cell Invasion through basement membrane: The netrin receptor DCC guides the way
Morrissey, M. A., Hagedorn, E. J., Sherwood D. R. (2013). Worm 2 (3) e26169-1-6. pdf
Morphogenesis of the Caenorhabditis elegans vulva
Schindler Adam J., Sherwood David R. (2013). WIREs Dev Biol. 2(1):75-95. pdf
2011
Cell Invasion Through Basement Membrane: The Anchor Cell Breaches the Barrier
Hagedorn, E.J. and Sherwood, D. R. (2011). Curr Opinion Cell Biol. 23(5): 589-9. pdf
The transcription factor HLH2/E/Daughterlessregulates anchor cell invasion in C. elegans
Schindler, A.J. and Sherwood, D.R. (2011). Dev. Biol. Sep 15;357(2):380-91. pdf
Cell Picture Show, Cell Motility
Hagedorn, E.J. and Sherwood, D.R. (2011). “WalkingThrough Walls”. http://www.cell.com/pictureshow/cell-motility
Dissection of Genetic Pathways in C. elegans
Wang, Z., and Sherwood, D.R. (2011). Molecular Genetics and Development – Methods in Cell Biol. 106:113-57. pdf
Basement membrane sliding and targeted adhesion remodels tissue boundaries during uterine-vulval attachment in C. elegans
Ihara, S., Hagedorn, E.J., Morrissey, M.A., Motegi, F., Kramer, J.M., Sherwood, D.R., (2011). Nat Cell Biol. Jun;13(6):641-51. pdf
Dispatch, Current Biology 9 August 2011, 21(15):R585-7
2010
VanHook PODCAST
David Q. Matus, David R. Sherwood, and Annalisa M. Sci Signal.,11 (2010) 3, Issue 121, p. pc10. Science Signaling Podcast_ 11 May 2010
Identification of novel regulators of cell invasion across basement membrane in vivo
Matus, D.Q., Li, X-Y., Durbin S., Agarwal, D., Chi, Q., Weiss, S.J., Sherwood, D.R. (2010). Sci Signal. 4:3(120): ra35. pdf supplemental material
Science, Editors Choice, 28 May 2010, p. 1077
Research Highlights in Nature Reviews Cancer, 27 May 2010; doi 10. 1038/nrc 2878
Roles for Netrin Signaling Outside of Axon Guidance: A View from of Worm
Ziel, J.W., Sherwood, D.R. (2010). Dev Dyn 239(5): 1296-305. pdf
2009
Integrin Acts Upstream of Netrin Signaling to Regulate Formation of the Anchor Cell’s Invasive Membrane in C. elegans
Hagedorn, E.J., Yashiro, H., Ziel, J.Z., Ihara, S., Wang, Z., and Sherwood, D.R. (2009). Dev. Cell 17, 187-198. pdf
Comment in Dev Cell. Integrins Anchor the Invasive Machinery (2009), 17(2): 158-60
An expression screen for RhoGEF genes involved in C. elegans gonadogenesis
Ziel, J.W., Matus, D.Q., Sherwood, D.R. (2009). Gene Expr Patterns 9(6): 397-403. pdf
David Sherwood: invasive procedures
Sherwood, D.R. (2009). Interview by Ben Short., J. Cell Biol, 185(4): 568-9. pdf
UNC-6 (netrin) orients the invasive membrane of the anchor cell in C. elegans
Ziel, J.W., Hagedorn, E.J., Audhya, A., Sherwood, D.R. (2009) Nat Cell Biol. 11(2): 183-9. pdf
2006
Cell invasion through basement membranes: an anchor of understanding
Sherwood, D. R. (2006). Trends Cell Biol. 16(5): 250-256. pdf
2005
Fos-1 promotes basement-membrane removal during anchor-cell invasion in C. elegans
Sherwood, D. R., Butler, J.A., Kramer, J.M., and Sternberg, P.W. (2005). Cell 121, 951-962. pdf Supplemental Data
Comment in: Cell. 2005 Jun17; 121(6): 816-7
Editorial in: Matrix Biology. 2006; 25(1):1-2.
2003
Anchor cell invasion into the vulval epithelium in C. elegans
Sherwood, D. R., and Sternberg, P.W. (2003). Dev. Cell 5, 21-31. pdf
Comment in: Dev Cell. 2003 Jul; 5(1):5-7
2002
Gene expression markers for Caenorhabditis elegans vulval cells
Inoue, T., Sherwood, D. R., Aspöck, G., Butler, J. A., Gupta, B. P., Kirouac, M., Wang, M., Lee, P.-Y., Kramer, J. M., Hope, I., Burglin, T.R., Sternberg, P.W. (2002). Mech. Dev. 119S, S203-S209. pdf
Caenorhabditis elegans cog-1 locus encodes a GTX/Nkx6.1 homeodomain proteins and regulates multiple aspects of reproductive system development
