Irala D, Wang S, Sakers K, Nagendren L, Ulloa Severino FP, Bindu DS, Savage JT, Eroglu C. Neuron. (2024). Astrocyte-secreted neurocan controls inhibitory synapse formation and function. https://doi.org/10.1016/j.neuron.2024.03.007
Ortiz CC, Eroglu C. Current Opinion in Cell Biology. (2024). Astrocyte signaling and interactions in Multiple Sclerosis. https://doi.org/10.1016/j.ceb.2023.102307.
Tan CX, Bindu DS, Hardin EJ, Sakers K, Baumert R, Ramirez JJ, Savage JT, Eroglu C. Journal of Cell Biology. (2023). δ-Catenin controls astrocyte morphogenesis via layer-specific astrocyte-neuron cadherin interactions. https://doi.org/10.1083/jcb.202303138.
Ulloa Severino FP, Lawal OO, Sakers K, Wang S, Kim N, Friedman AD, Johnson SA, Sriworarat C, Hughes RH, Soderling SH, Kim IH, Yin HH, Eroglu C. Nature Communications. (2023). Training-induced circuit-specific excitatory synaptogenesis in mice is required for effort control. https://doi.org/10.1038/s41467-023-41078-z
Chen X, Wolfe DA, Bindu DS, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan EE, Huang SF, Kumar SR, Arokiaraj CM, Plattner VM, Campos LJ, Mich JK, Monet D, Ngo V, Ding X, Omstead V, Weed N, Bishaw Y, Gore BB, Lein ES, Akrami A, Miller C, Levi BP, Keller A, Ting JT, Fox AS, Eroglu C, Gradinaru V. Nature Communications. (2023). Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. https://doi.org/10.1038/s41467-023-38582-7
Bindu DS, Tan CX, Savage JT, Eroglu C. bioRxiv. (2023). GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes. https://doi.org/10.1101%2F2023.01.17.524433 [preprint]
Savage JT, Ramirez JJ, Risher WC, Irala D, Eroglu C. bioRxiv. (2023). SynBot: An open-source image analysis software for automated quantification of synapses. https://doi.org/10.1101/2023.06.26.546578 [preprint]
Wang S, Bindu DS, Tan CX, Sakers K, Takano T, Salazar MPR, Dimond K, Soderling SH, La Spada AR, Eroglu C. bioRxiv. (2023). Astrocytic LRRK2 Controls Synaptic Connectivity through ERM Phosphorylation. https://doi.org/10.1101/2023.04.09.536178 [preprint]
Chen G, Luo H, Luo X, Singh SK, Ramirez JJ, James ML, Mathew JP, Berger M, Eroglu C, Ji R-R. JCI Insight. (2022).Sparcl1/Hevin drives inflammatory and neuropathic pain through astrocyte and NMDA receptor signaling. https://doi.org/10.1172/jci.insight.161028
Lawal O, Ulloa Severino FP, Eroglu C. Glia (2022). The role of astrocyte structural plasticity in regulating neural circuit function and behavior. Aug;70(8):1467-1483. doi: 10.1002/glia.24191.
Baumert R, Brose N, Eroglu C. Astrocytic traffic jams in the aging brain. Nat Aging (2022). https://doi.org/10.1038/s43587-022-00270-4.
Block CL, Eroglu O, Mague SD, Smith CJ, Ceasrine AM, Sriworarat C, Blount C, Beben KA, Malacon KE, Ndubuizu N, Talbot A, Gallagher NM, Chan Jo Y, Nyangacha T, Carlson DE, Dzirasa K, Eroglu C, Bilbo SD. Prenatal environmental stressors impair postnatal microglia function and adult behavior in males. Cell Rep. 2022 Aug 2;40(5):111161. doi: 10.1016/j.celrep.2022.111161. Featured on the cover.
Ramirez JJ, Bindu DS, Eroglu C. (2021) Building and destroying synaptic bridges: How do Hevin/Sparcl1, SPARC, and MDGAs modify trans-synaptic neurexin-neuroligin interactions? Structure Jul 1;29(7):635-637.
Baldwin, KT, Tan, CX, Strader, S, Jiang, C, Savage, JS, Estevez, R, Ji, R and Eroglu, C (2021), HepaCAM controls astrocyte self-organization and coupling. Neuron Jun 21:S0896-6273(21)00378-0. doi: 10.1016/j.neuron.2021.05.025. Online ahead of print. PMCID: In progress.
Tan CX, Eroglu C. Cell adhesion molecules regulating astrocyte-neuron interactions. Curr Opin Neurobiol. 2021 May 3;69:170-177.
Brennan FH, Noble BT, Wang Y, Guan Z, Davis H, Mo X, Harris C, Eroglu C, Ferguson AR, Popovich PG. Acute post-injury blockade of α2δ-1 calcium channel subunits prevents pathological autonomic plasticity after spinal cord injury. Cell Rep. 2021 Jan 26;34(4):108667.
Tan, C. X., Lane, C. and Eroglu, C. (2021). “Role of astrocytes in synapse formation and maturation”, Molecular mechanisms of neural development and insights into disease, Current Topics in Developmental Biology, Vol 142, edited by Bashaw, G., Elsevier. https://doi.org/10.1016/bs.ctdb.2020.12.010
Takano T, Wallace JT, Baldwin KT, Purkey A, Uezu A, Courtland JL, Soderblom EJ, Shimogori T, Maness PF, Eroglu C, Soderling SH (2020). Chemico-genetic discovery of astrocytic control of inhibition in vivo. Nature, Oct 11; https://doi.org/10.1038/s41586-020-2926-0. View the article.
Ostrovskaya OI, Cao G, Eroglu C, and Harris KM (2020). Developmental onset of enduring long-term potentiation in mouse hippocampus. Hippocampus, Sep 07; EPub: doi.org/10.1002/hipo.23257.
Risher WC and Eroglu C (2020). Astrocytes and Synaptogenesis. Volume: Synapse Development and Maturation, Comprehensive Developmental Neuroscience, edited by John Rubenstein, …, Jessica Cardin, ISBN 978-0-12-823672-7, Academic Press. View the book.
Risher WC and Eroglu C (2020). Emerging roles for α2δ subunits in calcium channel function and synaptic connectivity. Current opinion in neurobiology. Jun 7; 1363:162-169. View the article.
Luo L et. al, …Stogsdill JA, …, Eroglu C,… Kawabe HY, Craig AM (2020). Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors. Neuron, S0896-6273(20):30008-8. View the article.
Burrus CJ, McKinstry SU, Kim N, Ozlu MI, Santoki AV, Fang FY, Ma A, Karadeniz YB, Worthington AK, Dragatsis I, Zeitlin S, Yin HH, Eroglu C (2020). Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival. Cell Reports, 30(3):642-657. View the article.
Park J, Levic DS, Sumigray KD, Bagwell J, Eroglu O, Block CL, Eroglu C, Barry R, Lickwar CR, Rawls JF, Watts SA, Lechler T, Bagnat M* (2019). Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut. Dev. Cell, Aug 20. pii: S1534-5807(19)30661-6. View the article.
Sakers K and Eroglu C (2019). Control of neural development and function by glial neuroligins. Current opinion in neurobiology. Apr 13; 59:163-170. View PDF.
Baldwin KT and Eroglu C (2018). Astrocytes “Coordinate” Synapse Maturation and Plasticity. Neuron. Dec 5;100(5):1010-1012. View PDF.
Risher WC, Kim N, Koh S, Choi J-E, Mitev P, Spence EF, Pilaz L-J, Wang D, Feng G, Silver DL, Soderling SH, Yin HH and Eroglu C (2018). Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1. J Cell Biol., Jul 27. pii: jcb.201802057. doi: 10.1083/jcb.201802057. View PDF.
Koh S, Chen WJ, Dejneka NS, Harris IR, Lu B, Girman S, Saylor J, Wang S and Eroglu C (2018). Subretinal Human Umbilical Tissue-Derived Cell Transplantation Preserves Retinal Synaptic Connectivity and Attenuates Müller Glial Reactivity. J. Neurosci. 2018, Feb 5, 1532-17. View PDF.
E L, Zhou T, Liu D, Koh S, Chuang M, Sharma R, Pujol N, Chisholm AD, Eroglu C, Matsunami H, Yan D (2018). An antimicrobial peptide and its neuronal receptor regulate dendrite degeneration in aging and infection. Neuron, Jan 3;97(1):125-138. View the article. Request reprints c.eroglu@cellbio.duke.edu.
Stogsdill JA, Ramirez J, Liu D, Kim Y-H, Baldwin KT, Enustun E, Ejikeme T, Ji R-R and Eroglu C (2017). Astrocytic Neuroligins Control Astrocyte Morphogenesis and Synaptogenesis. Nature, 551, 192–197. View PDF.
Allen NJ and Eroglu C (2017). Cell biology of astrocyte-synapse interactions. Neuron 96, Issue 3, p697–708. View PDF.
Baldwin KT and Eroglu C (2017). Molecular mechanisms of astrocyte-induced synaptogenesis. Current opinion in neurobiology 42: 1-8. View PDF.
Gomez-Pastor R, Molzberger E, Neef D Jaeger A, Cabiscol E, McKinstry SU, Doss A, Aballay A, Lo D, Akimov SS, Ross CA, Eroglu C, Thiele D (2017). Prevention of Abnormal Degradation of the Neuronal Stress-Protective Transcription Factor HSF1 Ameliorates Huntington’s Disease. Nature Communications, Feb 13;8:14405. View PDF.
Stogsdill JA, and Eroglu C (2017). The interplay between neurons and glia in synapse development and plasticity. Current opinion in neurobiology 42: 1-8. View PDF.
Singh SK, Stogsdill JA, Pulimood NS, Dingsdale H, Kim YH, Pilaz LJ, Kim IH, Manhaes AC, Rodriguez-Junior WS, Pamukcu A, Enustun E, Ertuz Z, Scheiffele P, Soderling S, Silver DS, Ji R-R, Medina AE, Eroglu C (2016). Astrocytes assemble thalamocortical synapses by bridging neurexin1-alpha and neuroligin-1 via hevin. Cell, Jan 14:164(1-2):183-196. View PDF.
Koh S, Kim N-S, Yin HH, Harris I, Dejneka N and Eroglu C (2015). Human Umbilical Tissue-Derived Cells Promote Synapse Formation and Neurite Outgrowth via Thrombospondin Family Proteins. J. Neurosci. 2015, Nov 25: 35(47):15649 –15665. View PDF.
Risher ML, Sexton HG, Risher WC, Wilson W, Fleming RL, Madison RD, Moore SD, Eroglu C, Swartzwelder HS (2015) Adolescent Intermittent Alcohol Exposure: Dysregulation of thrombospondins and synapse formation are associated with decreased neuronal density in the adult hippocampus. Alcoholism: Clinical and Experimental Research. Nov 5. doi: 10.1111/acer.12913.
Risher M-L, Fleming R, Risher WC, Miller K, Klein R, Acheson S, Moore SD, Wilson W, Eroglu C, and Swartzwelder SH (2015). Adolescent intermittent alcohol exposure: persistence of structural and functional hippocampal immaturity into adulthood. Alcoholism: Clinical and Experimental Research. Apr 27. doi: 10.1111/acer.12725. View PDF.
Chung W-S, Allen NJ, Eroglu C, (2015). Astrocytes Control Synapse Formation, Function, and Elimination. Cold Spring Harb Perspect Biol. Published in Advance February 6, 2015, doi: 10.1101/cshperspect.a020370. View abstract. Request reprint by emailing to c.eroglu@cellbio.duke.edu.
Risher WC, Patel S, Kim IH, Uezu A, Bhagat S, Wilton DK, Pilaz L-J, Singh JA, Calhan OY, Silver DL, Stevens B, Calakos N, Soderling SH and Eroglu C (2014). Astrocytes refine cortical connectivity at dendritic spines. eLife Dec 17, 17:3. View PDF.
Risher W.C., Ustunkaya T., Singh J.A., and Eroglu C. (2014) Rapid Golgi Analysis Method for Efficient and Unbiased Classification of Dendritic Spines. PLoS ONE, Sep 10;9(9):e107591. View PDF.
McKinstry S.U., Karadeniz Y.B., Worthington, A.K., Hayrapetyan V.Y., Ozlu M.I., Serafin-Molina K., Risher W.C., Ustunkaya, T., Dragatsis, I., Zeitlin S., Yin H.H., Eroglu C. (2014) Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits. J. Neurosci. 2014 Jul 9:34(28):9455-72. View PDF.
Singh S.K. and Eroglu C. (2013). Neuroligins Provide Molecular Links between Syndromic and Non-Syndromic Autism. Sci. Signaling. Jul 9;6(283):re4. View PDF.
Benner E.J., Luciano D., Jo R., Lyons G., Paez-Gonzalez P., Abdi K., Sheng H., Warner D.S., Liu C., Eroglu C., Kuo C.T. (2013) Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. Nature 16;497(7449):369-73. View PDF.
Wan Y., Ade K., Caffall Z., Ozlu M.I., Eroglu C., Feng G., and Calakos N. (2013). Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder. Biol Psych. pii: S0006-3223(13)00048-6. View PDF.
Risher, W.C., and Eroglu, C. (2012). Thrombospondins as key regulators of synaptogenesis in the central nervous system. Matrix Biol 31, 170-177. View PDF.
Kim, D.S., Li, K.W., Boroujerdi, A., Peter Yu, Y., Zhou, C.Y., Deng, P., Park, J., Zhang, X., Lee, J., Corpe, M., Sharp K., Steward O., Eroglu C., Barres B., Zaucke F., Xu Z., and Luo Z.D. (2012). Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states. J Neurosci 32, 8977-8987. View PDF.
Kucukdereli, H., Allen, N.J., Lee, A.T., Feng, A., Ozlu, M.I., Conatser, L.M., Chakraborty, C., Workman, G., Weaver, M.S., Sage, E.H., Barres, B.A., Eroglu, C. (2011). Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC. Proceedings of the National Academy of Sciences of the United States of America 108, E440-449. View PDF.
Eroglu, C, Barres, B.A. (2010). Regulation of synaptic connectivity by glia. Nature, Nov 11;468(7321):223-31. View PDF.
Ippolito DM, Eroglu C (2010). Quantifying synapses: An immunocytochemistry based assay to quantify synapse number. JoVE., doi: 10.3791/2270. Read more information.
Bolton MM, and Eroglu C (2009). Look who is weaving the neural web: glial control of synapse formation. Current opinion in neurobiology 19: 491-497. View PDF.
Eroglu C (2009). Astrocyte-Secreted Matricellular Proteins in Central Nervous System Development and Function. Journal of Cell Communication and Signaling 3:167-176. View PDF.
Eroglu C, Allen NJ, Susman MW, O’Rourke NA, Park CY, Ozkan E, Chakraborty C, Mulinyawe SB, Annis DS, Huberman AD, Green EM, Lawler J, Dolmetsch R, Garcia KC, Smith SJ, Luo ZD, Rosenthal A, Mosher DF, Barres BA (2009). Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis. Cell 139: 380-392. View PDF.
Liauw J, Hoang S, Choi M, Eroglu C, Choi M, Sun GH, Percy M, Wildman-Tobriner B, Bliss T, Guzman RG, Barres BA and Steinberg GK (2008). Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke. Cereb. Blood Flow Metab. 10: 1722-32. View PDF.
